ketotifen has been researched along with Pulmonary Eosinophilia in 3 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response." | 3.68 | Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handley, DA | 1 |
| DeLeo, JJ | 1 |
| Havill, AM | 1 |
| Kings, MA | 1 |
| Chapman, I | 1 |
| Kristersson, A | 1 |
| Sanjar, S | 1 |
| Morley, J | 1 |
| Chihara, J | 1 |
| Kubo, H | 1 |
| Sakurada, R | 1 |
| Yamamoto, J | 1 |
| Nakano, N | 1 |
| Sugihara, R | 1 |
| Nakajima, S | 1 |
3 other studies available for ketotifen and Pulmonary Eosinophilia
| Article | Year |
|---|---|
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui | 1992 |
Human recombinant lymphokines and cytokines induce pulmonary eosinophilia in the guinea pig which is inhibited by ketotifen and AH 21-132.
Topics: Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Guinea Pigs; Ketotifen; Leukocy | 1990 |
[IgE-Fc receptor expressions on bronchoalveolar lavage (BAL) cells in a patient with eosinophilic pneumonia accompanied with bronchial asthma--the effect of ketotifen on their expression].
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Eo | 1989 |