ketotifen has been researched along with Pregnancy in 8 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pretreatment with ketotifen significantly increased the duration of pregnancy in sensitized animals, compared with untreated animals." | 3.72 | Induction of premature labor and delivery by allergic reaction and prevention by histamine H1 receptor antagonist. ( Bytautiene, E; El-Zeky, F; Garfield, RE; Romero, R; Saade, GR; Vedernikov, YP, 2004) |
| "In a postmarketing surveillance of ketotifen (Zaditen), an oral preparation for the prophylaxis of bronchial asthma, 8291 patients completed records every three months for one year." | 3.67 | Postmarketing surveillance: practical experience with ketotifen. ( Crowder, D; Maclay, WP; Spiro, S; Turner, P, 1984) |
| "The prophylaxis of childhood asthma is discussed under the headings of prevention by the pregnant mother in avoiding hypersensitizing foods and the adherence to breast feeding, immunotherapy of the child and chemoprophylaxis by sodium cromoglycate or ketotifen fumarate." | 3.67 | Prophylactic treatment of childhood asthma. ( Castello, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Molderings, GJ | 1 |
| Homann, J | 1 |
| Brettner, S | 1 |
| Raithel, M | 1 |
| Frieling, T | 1 |
| Azadi, L | 1 |
| Abbasi, H | 1 |
| Deemeh, MR | 1 |
| Tavalaee, M | 1 |
| Arbabian, M | 1 |
| Pilevarian, AA | 1 |
| Nasr-Esfahani, MH | 1 |
| Bytautiene, E | 1 |
| Romero, R | 1 |
| Vedernikov, YP | 1 |
| El-Zeky, F | 1 |
| Saade, GR | 1 |
| Garfield, RE | 1 |
| Freerksen, N | 1 |
| Betancourt, A | 1 |
| Maul, H | 1 |
| Wentz, M | 1 |
| Orise, P | 1 |
| Günter, HH | 1 |
| Sohn, C | 1 |
| Vedernikov, Y | 1 |
| Saade, G | 1 |
| Garfield, R | 1 |
| Herman, D | 1 |
| Vidart, JN | 1 |
| Maclay, WP | 1 |
| Crowder, D | 1 |
| Spiro, S | 1 |
| Turner, P | 1 |
| Guillouzo, A | 1 |
| Le Bigot, JF | 1 |
| Guguen-Guillouzo, C | 1 |
| Kiechel, JR | 1 |
| Castello, D | 1 |
1 review available for ketotifen and Pregnancy
| Article | Year |
|---|---|
[Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options].
Topics: Adult; Algorithms; Ascorbic Acid; Bone Marrow; Child; Combined Modality Therapy; Diagnosis, Differen | 2014 |
1 trial available for ketotifen and Pregnancy
| Article | Year |
|---|---|
Zaditen (Ketotifen), as mast cell blocker, improves sperm quality, chromatin integrity and pregnancy rate after varicocelectomy.
Topics: Animals; DNA Damage; Female; Histamine H1 Antagonists; Humans; Ketotifen; Male; Mast Cells; Pregnanc | 2011 |
6 other studies available for ketotifen and Pregnancy
| Article | Year |
|---|---|
Induction of premature labor and delivery by allergic reaction and prevention by histamine H1 receptor antagonist.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Cromolyn Sodium; Female; Guinea Pigs; Histamine H1 Antago | 2004 |
PAR-2 activating peptide-induced stimulation of pregnant rat myometrium contractile activity partly involves the other membrane receptors.
Topics: Animals; Atropine; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hydraz | 2007 |
[Risk evaluation and management of the pregnant asthmatic].
Topics: Adrenergic beta-Agonists; Asthma; Cromolyn Sodium; Female; Humans; Hydrocortisone; Ketotifen; Pregna | 1982 |
Postmarketing surveillance: practical experience with ketotifen.
Topics: Adolescent; Adult; Aged; Asthma; Child; Communication; Evaluation Studies as Topic; Female; Humans; | 1984 |
Presence of phase I and phase II drug metabolizing enzymes in cultured human foetal hepatocytes.
Topics: Cells, Cultured; Female; Fetus; Gestational Age; Glucuronates; Guanfacine; Guanidines; Humans; Ketot | 1982 |
Prophylactic treatment of childhood asthma.
Topics: Adult; Asthma; Breast Feeding; Child; Cromolyn Sodium; Desensitization, Immunologic; Female; Food Hy | 1986 |