Page last updated: 2024-10-30

ketotifen and Obesity

ketotifen has been researched along with Obesity in 4 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" In the present study, the effects of lime (Citrus aurantifolia) essential oils in reducing body weight, individually and in co-administration with ketotifen, an antihistaminic drug that causes weight gain, has been investigated using a mouse model."3.76Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice. ( Asnaashari, S; Delazar, A; Habibi, B; Hamedeyazdan, S; Nahar, L; Sarker, SD; Vasfi, R, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, X1
Huang, Q1
Wang, X1
Deng, Z1
Li, J1
Yan, X1
Jauhiainen, M1
Metso, J1
Libby, P1
Liu, J1
Shi, GP2
El-Haggar, SM1
Farrag, WF1
Kotkata, FA1
Asnaashari, S1
Delazar, A1
Habibi, B1
Vasfi, R1
Nahar, L1
Hamedeyazdan, S1
Sarker, SD1
Wang, J1

Trials

1 trial available for ketotifen and Obesity

ArticleYear
Effect of ketotifen in obese patients with type 2 diabetes mellitus.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:3

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Female; Huma

2015

Other Studies

3 other studies available for ketotifen and Obesity

ArticleYear
Dietary cholesterol is essential to mast cell activation and associated obesity and diabetes in mice.
    Biochimica et biophysica acta. Molecular basis of disease, 2019, 06-01, Volume: 1865, Issue:6

    Topics: Adipose Tissue; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; beta-N-Acetylhexosaminidases;

2019
Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:12

    Topics: Animals; Citrus aurantiifolia; Cyclohexenes; Gas Chromatography-Mass Spectrometry; Histamine H1 Anta

2010
Mast cell stabilization: novel medication for obesity and diabetes.
    Diabetes/metabolism research and reviews, 2011, Volume: 27, Issue:8

    Topics: Animals; Cromolyn Sodium; Diabetes Mellitus; Insulin Resistance; Ketotifen; Mast Cells; Mice; Obesit

2011