ketotifen has been researched along with Neurogenic Inflammation in 2 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Neurogenic Inflammation: Inflammation caused by an injurious stimulus of peripheral neurons and resulting in release of neuropeptides which affect vascular permeability and help initiate proinflammatory and immune reactions at the site of injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Toluene is a representative airborne occupational and domestic pollutant that causes eye and respiratory tract irritation." | 1.38 | Neurogenic airway microvascular leakage induced by toluene inhalation in rats. ( Kamijima, M; Miyake, M; Sakamoto, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Futamura, M | 1 |
| Goto, S | 1 |
| Kimura, R | 1 |
| Kimoto, I | 1 |
| Miyake, M | 2 |
| Ito, K | 1 |
| Sakamoto, T | 2 |
| Kamijima, M | 1 |
2 other studies available for ketotifen and Neurogenic Inflammation
| Article | Year |
|---|---|
Differential effects of topically applied formalin and aromatic compounds on neurogenic-mediated microvascular leakage in rat skin.
Topics: Administration, Topical; Animals; Antipruritics; Capillary Leak Syndrome; Capsaicin; Cell Degranulat | 2009 |
Neurogenic airway microvascular leakage induced by toluene inhalation in rats.
Topics: Animals; Bronchi; Dose-Response Relationship, Drug; Glycopeptides; Inhalation Exposure; Ketotifen; M | 2012 |