ketotifen has been researched along with Neurofibroma in 2 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Neurofibroma: A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Based on potential contributions of mast cells to neurofibroma-associated itching, pain, and tenderness, the mast cell blocker ketotifen fumarate (Zaditen, Sandoz Pharmaceuticals Corp, Hanover, NJ) has been proposed as a treatment for these symptoms." | 9.07 | A controlled multiphase trial of ketotifen to minimize neurofibroma-associated pain and itching. ( Riccardi, VM, 1993) |
| "Based on potential contributions of mast cells to neurofibroma-associated itching, pain, and tenderness, the mast cell blocker ketotifen fumarate (Zaditen, Sandoz Pharmaceuticals Corp, Hanover, NJ) has been proposed as a treatment for these symptoms." | 5.07 | A controlled multiphase trial of ketotifen to minimize neurofibroma-associated pain and itching. ( Riccardi, VM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bimbi, C | 1 |
| Riccardi, VM | 2 |
| Koumoundourou, D | 1 |
| Kyriakou, G | 1 |
1 trial available for ketotifen and Neurofibroma
| Article | Year |
|---|---|
A controlled multiphase trial of ketotifen to minimize neurofibroma-associated pain and itching.
Topics: Adult; Double-Blind Method; Female; Follow-Up Studies; Humans; Ketotifen; Male; Neurofibroma; Pain; | 1993 |
1 other study available for ketotifen and Neurofibroma
| Article | Year |
|---|---|
Ketotifen, mast cells and NF1 cutaneous neurofibromas: Compelling human data.
Topics: Humans; Ketotifen; Mast Cells; Neurofibroma; Skin Neoplasms | 2020 |