ketotifen has been researched along with Neoplasms in 3 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "Exosomes released from cancer cells support metastasis and growth of recipient cells and increase their resistance to chemotherapy." | 1.48 | Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin. ( Alawadhi, H; El-Awady, R; Harati, R; Khan, FM; Saleh, E; Zimmermann, WH, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Khan, FM | 1 |
| Saleh, E | 1 |
| Alawadhi, H | 1 |
| Harati, R | 1 |
| Zimmermann, WH | 1 |
| El-Awady, R | 1 |
| Briasoulis, E | 1 |
| Karavasilis, V | 1 |
| Pavlidis, N | 1 |
1 review available for ketotifen and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
1 trial available for ketotifen and Neoplasms
| Article | Year |
|---|---|
Successful rechallenge with taxanes following prophylactic ketotifen in patients who had developed severe hypersensitivity reactions.
Topics: Adult; Aged; Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Docetaxel; Drug Hypersensitivi | 2000 |
1 other study available for ketotifen and Neoplasms
| Article | Year |
|---|---|
Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Drug Resistance, Neoplasm; Exosomes; HeLa Cells; Humans; K | 2018 |