ketotifen has been researched along with Necrosis in 1 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketotifen was found to reverse eosinophil survival induced by interleukin-5." | 5.33 | Ketotifen induces primary necrosis of human eosinophils. ( Erjefält, J; Giembycz, MA; Hasala, H; Hasela, H; Kankaanranta, H; Malm-Erjefält, M; Moilanen, E; Zhang, X, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasala, H | 1 |
| Hasela, H | 1 |
| Malm-Erjefält, M | 1 |
| Erjefält, J | 1 |
| Giembycz, MA | 1 |
| Zhang, X | 1 |
| Moilanen, E | 1 |
| Kankaanranta, H | 1 |
1 other study available for ketotifen and Necrosis
| Article | Year |
|---|---|
Ketotifen induces primary necrosis of human eosinophils.
Topics: Apoptosis; Cell Survival; Cells, Cultured; DNA; Eosinophils; Flow Cytometry; Histamine H1 Antagonist | 2005 |