ketotifen has been researched along with Mitral Incompetence in 1 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mast cells are increased in isolated mitral regurgitation (MR) in the dog and may mediate extracellular matrix loss and left ventricular (LV) dilatation." | 1.36 | Mast cell stabilization decreases cardiomyocyte and LV function in dogs with isolated mitral regurgitation. ( Chen, Y; Dell'italia, LJ; Denney, T; Desai, R; Dillon, AR; Gladden, JD; Gupta, H; Killingsworth, C; Pat, B; Powell, PC; Tillson, M; Walcott, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pat, B | 1 |
| Killingsworth, C | 1 |
| Chen, Y | 1 |
| Gladden, JD | 1 |
| Walcott, G | 1 |
| Powell, PC | 1 |
| Denney, T | 1 |
| Gupta, H | 1 |
| Desai, R | 1 |
| Tillson, M | 1 |
| Dillon, AR | 1 |
| Dell'italia, LJ | 1 |
1 other study available for ketotifen and Mitral Incompetence
| Article | Year |
|---|---|
Mast cell stabilization decreases cardiomyocyte and LV function in dogs with isolated mitral regurgitation.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Anti-Allergic Agents; Collagen; Dogs; Extra | 2010 |