ketotifen has been researched along with Hyperemia in 9 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| " There were no significant differences in adverse events between groups." | 6.71 | Efficacy and safety of ketotifen fumarate 0.025% in the conjunctival antigen challenge model of ocular allergic conjunctivitis. ( Abelson, MB; Casey, R; Dubiner, H; Greiner, JV; Kapik, BM; Lonsdale, J; Mundorf, T; Parver, L; Shams, NB, 2003) |
| "Ketotifen was safe and statistically effective in reducing ocular itching and hyperemia associated with allergic conjunctivitis." | 5.10 | Efficacy of ketotifen fumarate 0.025% ophthalmic solution compared with placebo in the conjunctival allergen challenge model. ( Abelson, MB; Chapin, MJ; Kapik, BM; Shams, NB, 2003) |
| "Nine patients with Japanese cedar pollinosis who had no nasal or ocular symptoms were included in the present study, after obtaining informed consent in writing." | 2.72 | Effect of antihistamine eye drops on the conjunctival provocation test with Japanese cedar pollen allergen. ( Cheng, L; Dake, Y; Enomoto, K; Enomoto, T; Ikeda, H; Sakota, T; Shibano, A; Yajin, S; Yamanishi, E; Yoda, S, 2006) |
| " There were no significant differences in adverse events between groups." | 2.71 | Efficacy and safety of ketotifen fumarate 0.025% in the conjunctival antigen challenge model of ocular allergic conjunctivitis. ( Abelson, MB; Casey, R; Dubiner, H; Greiner, JV; Kapik, BM; Lonsdale, J; Mundorf, T; Parver, L; Shams, NB, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ben-Eli, H | 1 |
| Solomon, A | 1 |
| Abelson, MB | 2 |
| Chapin, MJ | 1 |
| Kapik, BM | 2 |
| Shams, NB | 2 |
| Greiner, JV | 1 |
| Mundorf, T | 1 |
| Dubiner, H | 1 |
| Lonsdale, J | 1 |
| Casey, R | 1 |
| Parver, L | 1 |
| Kawakubo, K | 1 |
| Akiba, Y | 1 |
| Adelson, D | 1 |
| Guth, PH | 2 |
| Engel, E | 1 |
| Taché, Y | 2 |
| Kaunitz, JD | 1 |
| Dake, Y | 1 |
| Enomoto, T | 1 |
| Cheng, L | 1 |
| Enomoto, K | 1 |
| Shibano, A | 1 |
| Ikeda, H | 1 |
| Yoda, S | 1 |
| Yajin, S | 1 |
| Sakota, T | 1 |
| Yamanishi, E | 1 |
| Király, A | 1 |
| Süto, G | 1 |
| Rydning, A | 2 |
| Lyng, O | 2 |
| Aase, S | 1 |
| Gronbech, JE | 1 |
| Ruh, J | 1 |
| Vogel, F | 1 |
| Schmidt, E | 1 |
| Adamsen, BL | 1 |
| Falkmer, S | 1 |
| Sandvik, AK | 1 |
| Grønbech, JE | 1 |
1 review available for ketotifen and Hyperemia
| Article | Year |
|---|---|
Topical antihistamines, mast cell stabilizers, and dual-action agents in ocular allergy: current trends.
Topics: Administration, Ophthalmic; Anti-Allergic Agents; Benzazepines; Conjunctivitis, Allergic; Cromolyn S | 2018 |
3 trials available for ketotifen and Hyperemia
| Article | Year |
|---|---|
Efficacy of ketotifen fumarate 0.025% ophthalmic solution compared with placebo in the conjunctival allergen challenge model.
Topics: Adult; Aged; Allergens; Anti-Allergic Agents; Conjunctiva; Conjunctivitis, Allergic; Double-Blind Me | 2003 |
Efficacy and safety of ketotifen fumarate 0.025% in the conjunctival antigen challenge model of ocular allergic conjunctivitis.
Topics: Adult; Aged; Allergens; Anti-Allergic Agents; Antigens; Conjunctiva; Conjunctivitis, Allergic; Doubl | 2003 |
Effect of antihistamine eye drops on the conjunctival provocation test with Japanese cedar pollen allergen.
Topics: Adult; Allergens; Antigens, Plant; Conjunctivitis, Allergic; Cryptomeria; Dose-Response Relationship | 2006 |
5 other studies available for ketotifen and Hyperemia
| Article | Year |
|---|---|
Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats.
Topics: Animals; Blood Pressure; Cell Count; Cell Degranulation; Connective Tissue Cells; Cromolyn Sodium; D | 2005 |
Ketotifen prevents gastric hyperemia induced by intracisternal thyrotropin-releasing hormone at a low dose.
Topics: Animals; Blood Pressure; Cisterna Magna; Gastric Acid; Gastric Mucosa; Hyperemia; Injections; Ketoti | 1997 |
Substance P may attenuate gastric hyperemia by a mast cell-dependent mechanism in the damaged gastric mucosa.
Topics: Acids; Animals; Anti-Asthmatic Agents; Aprotinin; Calcitonin Gene-Related Peptide; Cromolyn Sodium; | 1999 |
In vivo assessment of villous microcirculation in the rat small intestine in indomethacin-induced inflammation: role of mast-cell stabilizer Ketotifen.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Blood Flow Veloc | 2000 |
Mast cells are involved in the gastric hyperemic response to acid back diffusion via release of histamine.
Topics: Acids; Animals; Cell Count; Diffusion; Gastric Mucosa; Histamine H1 Antagonists; Histamine Release; | 2001 |