ketotifen has been researched along with Human Trichinellosis in 7 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with ketotifen prevented hypermotility and mast cell hyperplasia and diminished mucosal mast cell activity." | 5.33 | Mast cell stabilizer ketotifen [4-(1-methyl-4-piperidylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one fumarate] prevents mucosal mast cell hyperplasia and intestinal dysmotility in experimental Trichinella spiralis inflammation in the rat. ( Porras, M; Serna, H; Vergara, P, 2006) |
| " The anti-angiogenic potential of albendazole suggests that the action of this anti-helminthic during trichinellosis is not confined to structural damage to the parasite cuticle but includes an effect on host immunopathological response." | 4.02 | Effect of mast cell stabilization on angiogenesis in primary and secondary experimental Trichinella spiralis infection. ( Abdel-Aal, AA; Abdeltawab, MSA; Al-Antably, AS; Anis, SE; Badawi, M; El-Dardiry, MA; El-Sherbini, M; Hassan, MA; Khaled, BA, 2021) |
| "The treatment with ketotifen prevented hypermotility and mast cell hyperplasia and diminished mucosal mast cell activity." | 1.33 | Mast cell stabilizer ketotifen [4-(1-methyl-4-piperidylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one fumarate] prevents mucosal mast cell hyperplasia and intestinal dysmotility in experimental Trichinella spiralis inflammation in the rat. ( Porras, M; Serna, H; Vergara, P, 2006) |
| "Ketotifen was used as an anti-allergic agent to study the relationship between eosinophil-related responses and IgG1 and IgG2a antibody responses in BALB/c mice infected with Trichinella spiralis." | 1.31 | Immune response to Trichinella spiralis larvae after treatment with the anti-allergic compound ketotifen. ( Doligalska, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| El-Dardiry, MA | 1 |
| Abdel-Aal, AA | 2 |
| Abdeltawab, MSA | 1 |
| El-Sherbini, M | 1 |
| Hassan, MA | 1 |
| Badawi, M | 1 |
| Anis, SE | 1 |
| Khaled, BA | 1 |
| Al-Antably, AS | 1 |
| Fernández-Blanco, JA | 2 |
| Hollenberg, MD | 1 |
| MartÃnez, V | 1 |
| Vergara, P | 2 |
| Doligalska, M | 4 |
| Laskowska, M | 2 |
| Serna, H | 1 |
| Porras, M | 1 |
1 review available for ketotifen and Human Trichinellosis
| Article | Year |
|---|---|
[Effect of ketotifen on the immune response in BALB/c mice infected with Trichinella spiralis].
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Eosinophils; Histamine H1 Antagonists; Interleuki | 2000 |
6 other studies available for ketotifen and Human Trichinellosis
| Article | Year |
|---|---|
Effect of mast cell stabilization on angiogenesis in primary and secondary experimental Trichinella spiralis infection.
Topics: Albendazole; Animals; Anthelmintics; Drug Therapy, Combination; Female; Humans; Ketotifen; Mast Cell | 2021 |
PAR-2-mediated control of barrier function and motility differs between early and late phases of postinfectious gut dysfunction in the rat.
Topics: Animals; Gastroenteritis; Gastrointestinal Motility; Gastrointestinal Tract; Ketotifen; Male; Mast C | 2013 |
The mucosal mast cell and IgA plasma cell responses to primary Trichinelia spiralis infection in BALB/c mice treated with ketotifen.
Topics: Animals; Antibodies, Helminth; Histamine H1 Antagonists; Immunoglobulin A; Intestinal Mucosa; Ketoti | 2001 |
Mast cell stabilizer ketotifen [4-(1-methyl-4-piperidylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one fumarate] prevents mucosal mast cell hyperplasia and intestinal dysmotility in experimental Trichinella spiralis inflammation in the rat.
Topics: Animals; Cell Count; Cell Size; Cholecystokinin; Chymases; Cyclooxygenase 2; Gastrointestinal Motili | 2006 |
Immune response to Trichinella spiralis larvae after treatment with the anti-allergic compound ketotifen.
Topics: Animals; Anti-Allergic Agents; Antibodies, Helminth; Electrophoresis, Polyacrylamide Gel; Enzyme-Lin | 2000 |
Inhibition of the protective IgA response by ketotifen is related to the inflammatory reaction in the peritoneal cavity and intestinal mucosa of BALB/c mice infected with Trichinella spiralis.
Topics: Animals; Anti-Allergic Agents; Antibodies, Helminth; Eosinophils; Host-Parasite Interactions; Immuno | 2000 |