ketotifen has been researched along with Granulomas in 2 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the role of mast cells in granuloma-associated angiogenesis in rat by using: (i) a mast cell membrane stabilizer, ketotifen; (ii) a mast cell depleting agent, compound 48/80." | 3.73 | Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5. ( Di Rosa, M; Iuvone, T; Peticca, M; Pietropaolo, C; Russo, A; Russo, G, 2005) |
| "We report two cases of patients with cheilitis granulomatosis treated successfully with tranilast and ketotifen, both of which are known to be potent inhibitors or mediator release from mast cells." | 3.67 | [Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis]. ( Chiba, M; Kobayashi, M; Nagashima, M; Shiohara, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, A | 1 |
| Russo, G | 1 |
| Peticca, M | 1 |
| Pietropaolo, C | 1 |
| Di Rosa, M | 1 |
| Iuvone, T | 1 |
| Chiba, M | 1 |
| Kobayashi, M | 1 |
| Shiohara, T | 1 |
| Nagashima, M | 1 |
2 other studies available for ketotifen and Granulomas
| Article | Year |
|---|---|
Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5.
Topics: Animals; Cell Degranulation; Gene Expression; Granuloma; Ketotifen; Male; Mast Cells; Neovasculariza | 2005 |
[Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis].
Topics: Adolescent; Adult; Biological Factors; Cell Count; Cheilitis; Female; Granuloma; Humans; Ketotifen; | 1989 |