ketotifen has been researched along with Granuloma in 2 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the role of mast cells in granuloma-associated angiogenesis in rat by using: (i) a mast cell membrane stabilizer, ketotifen; (ii) a mast cell depleting agent, compound 48/80." | 3.73 | Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5. ( Di Rosa, M; Iuvone, T; Peticca, M; Pietropaolo, C; Russo, A; Russo, G, 2005) |
| "We report two cases of patients with cheilitis granulomatosis treated successfully with tranilast and ketotifen, both of which are known to be potent inhibitors or mediator release from mast cells." | 3.67 | [Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis]. ( Chiba, M; Kobayashi, M; Nagashima, M; Shiohara, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, A | 1 |
| Russo, G | 1 |
| Peticca, M | 1 |
| Pietropaolo, C | 1 |
| Di Rosa, M | 1 |
| Iuvone, T | 1 |
| Chiba, M | 1 |
| Kobayashi, M | 1 |
| Shiohara, T | 1 |
| Nagashima, M | 1 |
2 other studies available for ketotifen and Granuloma
| Article | Year |
|---|---|
Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5.
Topics: Animals; Cell Degranulation; Gene Expression; Granuloma; Ketotifen; Male; Mast Cells; Neovasculariza | 2005 |
[Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis].
Topics: Adolescent; Adult; Biological Factors; Cell Count; Cheilitis; Female; Granuloma; Humans; Ketotifen; | 1989 |