Page last updated: 2024-10-30

ketotifen and Granuloma

ketotifen has been researched along with Granuloma in 2 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Research Excerpts

ExcerptRelevanceReference
"We investigated the role of mast cells in granuloma-associated angiogenesis in rat by using: (i) a mast cell membrane stabilizer, ketotifen; (ii) a mast cell depleting agent, compound 48/80."3.73Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5. ( Di Rosa, M; Iuvone, T; Peticca, M; Pietropaolo, C; Russo, A; Russo, G, 2005)
"We report two cases of patients with cheilitis granulomatosis treated successfully with tranilast and ketotifen, both of which are known to be potent inhibitors or mediator release from mast cells."3.67[Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis]. ( Chiba, M; Kobayashi, M; Nagashima, M; Shiohara, T, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Russo, A1
Russo, G1
Peticca, M1
Pietropaolo, C1
Di Rosa, M1
Iuvone, T1
Chiba, M1
Kobayashi, M1
Shiohara, T1
Nagashima, M1

Other Studies

2 other studies available for ketotifen and Granuloma

ArticleYear
Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5.
    British journal of pharmacology, 2005, Volume: 145, Issue:1

    Topics: Animals; Cell Degranulation; Gene Expression; Granuloma; Ketotifen; Male; Mast Cells; Neovasculariza

2005
[Successful treatment of cheilitis granulomatosis with potent inhibitors of mediator release--possible involvement of mast cells in the pathogenesis].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1989, Volume: 99, Issue:8

    Topics: Adolescent; Adult; Biological Factors; Cell Count; Cheilitis; Female; Granuloma; Humans; Ketotifen;

1989