Page last updated: 2024-10-30

ketotifen and Geographic Atrophy

ketotifen has been researched along with Geographic Atrophy in 1 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Geographic Atrophy: A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.

Research Excerpts

ExcerptRelevanceReference
"This study evaluates whether topical ketotifen fumarate (KTF) can prevent geographic atrophy (GA)-like phenotypes in a rat model."8.02Topical Ketotifen Fumarate Inhibits Choroidal Mast Cell Degranulation and Loss of Retinal Pigment Epithelial Cells in Rat Model for Geographic Atrophy. ( Alt, J; Bhutto, IA; Edwards, MM; Grebe, RR; Lutty, GA; Nizawa, T; Rais, R; Tiwari, A, 2021)
"This study evaluates whether topical ketotifen fumarate (KTF) can prevent geographic atrophy (GA)-like phenotypes in a rat model."4.02Topical Ketotifen Fumarate Inhibits Choroidal Mast Cell Degranulation and Loss of Retinal Pigment Epithelial Cells in Rat Model for Geographic Atrophy. ( Alt, J; Bhutto, IA; Edwards, MM; Grebe, RR; Lutty, GA; Nizawa, T; Rais, R; Tiwari, A, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Nizawa, T1
Bhutto, IA1
Tiwari, A1
Grebe, RR1
Alt, J1
Rais, R1
Edwards, MM1
Lutty, GA1

Other Studies

1 other study available for ketotifen and Geographic Atrophy

ArticleYear
Topical Ketotifen Fumarate Inhibits Choroidal Mast Cell Degranulation and Loss of Retinal Pigment Epithelial Cells in Rat Model for Geographic Atrophy.
    Translational vision science & technology, 2021, 12-01, Volume: 10, Issue:14

    Topics: Animals; Cell Degranulation; Choroid; Chromatography, Liquid; Epithelial Cells; Geographic Atrophy;

2021