ketotifen has been researched along with Eosinophilia, Tropical in 17 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eosinophilic peritonitis is frequently observed in patients of all ages started on peritoneal dialysis." | 5.30 | Resolution of eosinophilic peritonitis with ketotifen. ( Chan, TM; Lo, CY; Lo, WK; Tang, S, 1997) |
| "A 30-year-old male with eosinophilic fasciitis (EF) associated with morphoea and vitiligo is described." | 5.28 | Ketotifen--a therapeutic agent of eosinophilic fasciitis? ( Ching, DW; Leibowitz, MR, 1992) |
| "The effects of betotastine besilate (betotastine: TAU-284), a novel antiallergic drug, on homologous passive cutaneous anaphylaxis (PCA), mediator-induced cutaneous reaction, antigen-induced asthmatic responses and platelet-activating factor (PAF)-induced airway eosinophilia in several animal models, were compared to ketotifen." | 3.70 | Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen. ( Inagaki, N; Koda, A; Nagai, H; Ueno, M, 1998) |
| "Cetirizine was significantly more effective at reducing the mean rhinorrhea score compared with oxatomide for both weeks 8 and 12 (P < 0." | 2.70 | The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis. ( Hsieh, JC; Lai, DS; Lee, HS; Lin, KL; Lue, KH, 2002) |
| " Children with newly or previously diagnosed ulcerative colitis with mild-moderate disease activity were treated with ketotifen at a dosage of 4 mg daily for eight weeks." | 2.69 | Ketotifen therapy for acute ulcerative colitis in children: a pilot study. ( Griffiths, AM; Jones, NL; Roifman, CM; Sherman, P, 1998) |
| "Eosinophilic cystitis is rare in children." | 2.41 | Eosinophilic cystitis. ( de Jong, TP; Nikkels, PG; Verhagen, PC, 2001) |
| "Of these, 29 (33%) had eosinophilic esophagitis (EoE), and 10 (11%) had eosinophilic gastritis, gastroenteritis or enterocolitis." | 1.62 | Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up. ( Arikan, C; Can, D; Doganay, L; Ozdogan, E, 2021) |
| "A rare association between autism and microscopic eosinophilic colitis in 2 children is reported through retrospective chart review." | 1.36 | Childhood autism and eosinophilic colitis. ( Chen, B; El-Matary, W; Girgis, S, 2010) |
| "Ketotifen treatment does not appear to prohibit or reverse the inflammatory process in the gastric mucosa in EGE, although long-term effects of steroids may be avoided." | 1.35 | Longstanding eosinophilic gastroenteritis of more than 20 years. ( Freeman, HJ, 2009) |
| "We report here two patients with ulcerative colitis who were initially diagnosed as eosinophilic colitis based on histopathological examination during their first attacks." | 1.33 | Dense eosinophilic infiltration of the mucosa preceding ulcerative colitis and mimicking eosinophilic colitis: report of two cases. ( Akin, O; Doğusoy, G; Hatemi, I; Uzunismail, H, 2006) |
| "Ketotifen was used as an anti-allergic agent to study the relationship between eosinophil-related responses and IgG1 and IgG2a antibody responses in BALB/c mice infected with Trichinella spiralis." | 1.31 | Immune response to Trichinella spiralis larvae after treatment with the anti-allergic compound ketotifen. ( Doligalska, M, 2000) |
| "Eosinophilic peritonitis is frequently observed in patients of all ages started on peritoneal dialysis." | 1.30 | Resolution of eosinophilic peritonitis with ketotifen. ( Chan, TM; Lo, CY; Lo, WK; Tang, S, 1997) |
| "Eosinophilic gastroenteritis is a rare condition of unknown etiology characterized by peripheral eosinophilia, eosinophilic infiltration of the gastrointestinal tract, and gastrointestinal symptomatology." | 1.29 | Eosinophilic gastroenteritis. ( Hodges, WG; Huggins, TL; Lee, EL; Lee, M, 1996) |
| "A 30-year-old male with eosinophilic fasciitis (EF) associated with morphoea and vitiligo is described." | 1.28 | Ketotifen--a therapeutic agent of eosinophilic fasciitis? ( Ching, DW; Leibowitz, MR, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Ozdogan, E | 1 |
| Doganay, L | 1 |
| Can, D | 1 |
| Arikan, C | 1 |
| Hui, CK | 1 |
| Hui, NK | 1 |
| Freeman, HJ | 1 |
| Chen, B | 1 |
| Girgis, S | 1 |
| El-Matary, W | 1 |
| Lai, DS | 1 |
| Lue, KH | 1 |
| Hsieh, JC | 1 |
| Lin, KL | 1 |
| Lee, HS | 1 |
| Uzunismail, H | 1 |
| Hatemi, I | 1 |
| Doğusoy, G | 1 |
| Akin, O | 1 |
| Iwama, T | 1 |
| Nagai, H | 2 |
| Tsuruoka, N | 1 |
| Koda, A | 2 |
| Lee, M | 1 |
| Hodges, WG | 1 |
| Huggins, TL | 1 |
| Lee, EL | 1 |
| Tang, S | 1 |
| Lo, CY | 1 |
| Lo, WK | 1 |
| Chan, TM | 1 |
| Jones, NL | 1 |
| Roifman, CM | 2 |
| Griffiths, AM | 1 |
| Sherman, P | 1 |
| Ueno, M | 1 |
| Inagaki, N | 1 |
| Doligalska, M | 1 |
| Verhagen, PC | 1 |
| Nikkels, PG | 1 |
| de Jong, TP | 1 |
| Katsinelos, P | 1 |
| Pilpilidis, I | 1 |
| Xiarchos, P | 1 |
| Christodoulou, K | 1 |
| Papagiannis, A | 1 |
| Tsolkas, P | 1 |
| Capelidis, P | 1 |
| Vasiliadis, I | 1 |
| Ching, DW | 1 |
| Leibowitz, MR | 1 |
| Melamed, I | 1 |
| Feanny, SJ | 1 |
| Sherman, PM | 1 |
| Schmelás, A | 1 |
| Drobnitsch, I | 1 |
| Schneider, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Omalizumab in Eosinophilic Gastroenteritis[NCT00084097] | Phase 2 | 30 participants | Interventional | 2004-06-02 | Completed | ||
| Pilot Study of Omalizumab (Xolair) in Hyper IgE (Job's) Syndrome[NCT00260702] | Phase 1 | 1 participants (Actual) | Interventional | 2005-11-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketotifen and Eosinophilia, Tropical
| Article | Year |
|---|---|
Eosinophilic cystitis.
Topics: Adolescent; Anti-Allergic Agents; Child; Child, Preschool; Chronic Disease; Cystitis; Enuresis; Eosi | 2001 |
2 trials available for ketotifen and Eosinophilia, Tropical
| Article | Year |
|---|---|
The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis.
Topics: Allergens; Animals; Anti-Allergic Agents; Blood Proteins; Cetirizine; Child; Conjunctivitis, Allergi | 2002 |
Ketotifen therapy for acute ulcerative colitis in children: a pilot study.
Topics: Child; Colitis, Ulcerative; Colon; Eosinophilia; Female; Histamine H1 Antagonists; Humans; Intestina | 1998 |
14 other studies available for ketotifen and Eosinophilia, Tropical
| Article | Year |
|---|---|
Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up.
Topics: Age Factors; Anti-Allergic Agents; Biliary Atresia; Budesonide; Child; Child, Preschool; Cholestasis | 2021 |
A Prospective Study on the Prevalence, Extent of Disease and Outcome of Eosinophilic Gastroenteritis in Patients Presenting with Lower Abdominal Symptoms.
Topics: Abdominal Pain; Acetates; Adolescent; Adult; Anti-Inflammatory Agents; Colon, Descending; Colon, Sig | 2018 |
Longstanding eosinophilic gastroenteritis of more than 20 years.
Topics: Adult; Disease Progression; Endoscopy, Digestive System; Eosinophilia; Eosinophils; Gastric Mucosa; | 2009 |
Childhood autism and eosinophilic colitis.
Topics: Autistic Disorder; Child; Colitis; Diagnosis, Differential; Eosinophilia; Histamine H1 Antagonists; | 2010 |
Dense eosinophilic infiltration of the mucosa preceding ulcerative colitis and mimicking eosinophilic colitis: report of two cases.
Topics: Adolescent; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Azathioprine; Colitis, Ulcerative | 2006 |
Effect of murine recombinant interleukin-5 on bronchial reactivity in guinea-pigs.
Topics: Animals; Bronchial Hyperreactivity; Cromolyn Sodium; Eosinophilia; Guinea Pigs; Interleukin-5; Ketot | 1993 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Resolution of eosinophilic peritonitis with ketotifen.
Topics: Aged; Eosinophilia; Histamine H1 Antagonists; Humans; Ketotifen; Male; Peritoneal Dialysis; Peritoni | 1997 |
Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Disease Models, Animal; Eosinophilia; Eo | 1998 |
Immune response to Trichinella spiralis larvae after treatment with the anti-allergic compound ketotifen.
Topics: Animals; Anti-Allergic Agents; Antibodies, Helminth; Electrophoresis, Polyacrylamide Gel; Enzyme-Lin | 2000 |
Oral administration of ketotifen in a patient with eosinophilic colitis and severe osteoporosis.
Topics: Administration, Oral; Aged; Anti-Allergic Agents; Colitis; Eosinophilia; Female; Humans; Ketotifen; | 2002 |
Ketotifen--a therapeutic agent of eosinophilic fasciitis?
Topics: Adult; Eosinophilia; Fasciitis; Follow-Up Studies; Humans; Ketotifen; Male; Scleroderma, Localized; | 1992 |
Benefit of ketotifen in patients with eosinophilic gastroenteritis.
Topics: Adolescent; Adult; Child; Eosinophilia; Female; Gastroenteritis; Humans; Immunoglobulin E; Ketotifen | 1991 |
Hypereosinophilic dermatitis with response to ketotifen and sulfone.
Topics: Aged; Dermatitis; Drug Therapy, Combination; Eosinophilia; Humans; Ketotifen; Male; Sulfones | 1986 |