ketotifen has been researched along with Eosinophilia, Pulmonary in 3 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response." | 3.68 | Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handley, DA | 1 |
| DeLeo, JJ | 1 |
| Havill, AM | 1 |
| Kings, MA | 1 |
| Chapman, I | 1 |
| Kristersson, A | 1 |
| Sanjar, S | 1 |
| Morley, J | 1 |
| Chihara, J | 1 |
| Kubo, H | 1 |
| Sakurada, R | 1 |
| Yamamoto, J | 1 |
| Nakano, N | 1 |
| Sugihara, R | 1 |
| Nakajima, S | 1 |
3 other studies available for ketotifen and Eosinophilia, Pulmonary
| Article | Year |
|---|---|
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui | 1992 |
Human recombinant lymphokines and cytokines induce pulmonary eosinophilia in the guinea pig which is inhibited by ketotifen and AH 21-132.
Topics: Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Guinea Pigs; Ketotifen; Leukocy | 1990 |
[IgE-Fc receptor expressions on bronchoalveolar lavage (BAL) cells in a patient with eosinophilic pneumonia accompanied with bronchial asthma--the effect of ketotifen on their expression].
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Eo | 1989 |