ketotifen has been researched along with Eczema, Atopic in 26 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the prophylactic effect of ketotifen against the onset of asthma we selected 121 infants with atopic dermatitis, without any history suggestive of asthma (cough and/or wheezing)." | 9.07 | Prevention of asthma by ketotifen in infants with atopic dermatitis. ( Baba, M; Iikura, Y; Mikawa, H; Naspitz, CK; Nishima, S; Sole, D; Talaricoficho, S, 1992) |
| "We tested the effect of Ketotifen (4-(1-methyl-4-piperidylidene)-4H- benzo[4,5] cyclohepta[1,2-b]thiophen-10(9H)-one hydrogen (fumarate) on the induction of allergen-induced IL-2 responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma." | 7.68 | Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma. ( Akasaka, T; Baba, M; Maeda, K; Noma, T; Yata, J; Yoshizawa, I, 1990) |
| "To evaluate the prophylactic effect of ketotifen against the onset of asthma we selected 121 infants with atopic dermatitis, without any history suggestive of asthma (cough and/or wheezing)." | 5.07 | Prevention of asthma by ketotifen in infants with atopic dermatitis. ( Baba, M; Iikura, Y; Mikawa, H; Naspitz, CK; Nishima, S; Sole, D; Talaricoficho, S, 1992) |
| "We tested the effect of Ketotifen (4-(1-methyl-4-piperidylidene)-4H- benzo[4,5] cyclohepta[1,2-b]thiophen-10(9H)-one hydrogen (fumarate) on the induction of allergen-induced IL-2 responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma." | 3.68 | Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma. ( Akasaka, T; Baba, M; Maeda, K; Noma, T; Yata, J; Yoshizawa, I, 1990) |
| "Of these, 29 (33%) had eosinophilic esophagitis (EoE), and 10 (11%) had eosinophilic gastritis, gastroenteritis or enterocolitis." | 1.62 | Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up. ( Arikan, C; Can, D; Doganay, L; Ozdogan, E, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 11 (42.31) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ozdogan, E | 1 |
| Doganay, L | 1 |
| Can, D | 1 |
| Arikan, C | 1 |
| Yoshihara, S | 1 |
| Ono, M | 1 |
| Yamada, Y | 1 |
| Fukuda, H | 1 |
| Abe, T | 1 |
| Arisaka, O | 1 |
| Yokoyama, H | 1 |
| Hirose, M | 1 |
| Uematsu, M | 1 |
| Haginoya, K | 1 |
| Iinuma, K | 1 |
| Kimura, S | 1 |
| Balabolkin, II | 1 |
| Matus, NI | 1 |
| DeShazo, RD | 1 |
| Levinson, AI | 1 |
| Dvorak, HF | 1 |
| Sokolova, TS | 1 |
| Reviakina, VA | 1 |
| Partsalis, EM | 1 |
| Botvin'eva, VV | 1 |
| Zakhidov, IuV | 1 |
| Kondo, N | 1 |
| Fukutomi, O | 1 |
| Kameyama, T | 1 |
| Nishida, T | 1 |
| Li, GP | 1 |
| Agata, H | 1 |
| Shinbara, M | 1 |
| Shinoda, S | 1 |
| Yano, M | 1 |
| Orii, T | 1 |
| Mancini, S | 1 |
| Fierimonte, V | 1 |
| Viviano, MT | 1 |
| Parisi, G | 1 |
| Zanali, S | 1 |
| Parisi, MC | 1 |
| Kanny, G | 1 |
| Hatahet, R | 1 |
| Moneret-Vautrin, DA | 1 |
| Kohler, C | 1 |
| Bellut, A | 1 |
| Ganir, EM | 1 |
| Capulong, MC | 1 |
| Tahara, K | 1 |
| Akasawa, A | 1 |
| Iikura, Y | 3 |
| García, G | 1 |
| DeMora, F | 1 |
| Ferrer, L | 1 |
| Puigdemont, A | 1 |
| Yamanaka, K | 1 |
| Kuwashima, K | 1 |
| Naspitz, CK | 1 |
| Mikawa, H | 2 |
| Talaricoficho, S | 1 |
| Baba, M | 3 |
| Sole, D | 1 |
| Nishima, S | 2 |
| Tsuda, S | 1 |
| Kato, K | 1 |
| Miyasato, M | 1 |
| Sasai, Y | 1 |
| Maeda, K | 2 |
| Akasaka, T | 2 |
| Masaki, T | 1 |
| Arita, M | 1 |
| Niiya, H | 1 |
| Koya, N | 1 |
| Deeva, TF | 1 |
| Cheburkin, AA | 1 |
| Chistiakov, GM | 1 |
| Basova, EN | 1 |
| Tsvetkova, EI | 1 |
| Kliubina, AO | 1 |
| Sviatkina, OB | 1 |
| Noma, T | 1 |
| Yoshizawa, I | 1 |
| Yata, J | 1 |
| Molkhous, P | 1 |
| Dupont, C | 1 |
| Yoshida, H | 1 |
| Niimura, M | 1 |
| Ueda, H | 1 |
| Imaura, S | 1 |
| Yamamoto, S | 1 |
| Kukita, A | 1 |
| Sergeev, IuV | 2 |
| Zimin, IuI | 1 |
| Reznikov, IuP | 1 |
| Malyshev, VS | 1 |
| Pimenova, NS | 1 |
| Lipets, ME | 1 |
| Lopatko, VN | 1 |
| Collins-Williams, C | 1 |
| Morris, EC | 1 |
| Potekaev, NS | 1 |
| Schmidt-Redemann, B | 1 |
| Brenneisen, P | 1 |
| Schmidt-Redemann, W | 1 |
| Gonda, S | 1 |
| Ito, S | 1 |
| Hiratani, M | 1 |
| Ueda, S | 1 |
| Muto, K | 1 |
2 reviews available for ketotifen and Eczema, Atopic
| Article | Year |
|---|---|
[Effectiveness of the use of zaditen in allergic dermatoses and the dermorespiratory syndrome in children].
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Histamine H1 Antagoni | 1983 |
Pharmacotherapy of allergic disease.
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Aged; Anaphylax | 1987 |
7 trials available for ketotifen and Eczema, Atopic
| Article | Year |
|---|---|
Early intervention with suplatast tosilate for prophylaxis of pediatric atopic asthma: a pilot study.
Topics: Allergens; Animals; Anti-Allergic Agents; Arylsulfonates; Asthma; Chemoprevention; Dermatitis, Atopi | 2009 |
[Effectiveness of the use of zaditen in allergic dermatoses and the dermorespiratory syndrome in children].
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Histamine H1 Antagoni | 1983 |
Suppression of proliferative responses of lymphocytes to food antigens by an anti-allergic drug, ketotifen fumarate, in patients with food-sensitive atopic dermatitis.
Topics: Child, Preschool; Depression, Chemical; Dermatitis, Atopic; Double-Blind Method; Epitopes; Food Hype | 1994 |
Allergy and intolerance to flavouring agents in atopic dermatitis in young children.
Topics: Allergens; Balsams; Benzaldehydes; Child, Preschool; Combined Modality Therapy; Cromolyn Sodium; Cro | 1994 |
Prevention of asthma by ketotifen in infants with atopic dermatitis.
Topics: Asthma; Child, Preschool; Dermatitis, Atopic; Dose-Response Relationship, Drug; Double-Blind Method; | 1992 |
[A double blind study of the effectiveness of ketotifen in preventing the development of asthma in atopic dermatitis patients].
Topics: Age Factors; Asthma; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Humans; Infant; Keto | 1991 |
Clinical evaluation of ketotifen syrup on atopic dermatitis: a comparative multicenter double-blind study of ketotifen and clemastine.
Topics: Clemastine; Clinical Trials as Topic; Dermatitis, Atopic; Double-Blind Method; Humans; Ketotifen; Py | 1989 |
18 other studies available for ketotifen and Eczema, Atopic
| Article | Year |
|---|---|
Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up.
Topics: Age Factors; Anti-Allergic Agents; Biliary Atresia; Budesonide; Child; Child, Preschool; Cholestasis | 2021 |
Ketotifen overdose in infancy associated with development of epilepsy and mild mental retardation.
Topics: Dermatitis, Atopic; Drug Overdose; Epilepsy; Histamine H1 Antagonists; Humans; Infant; Intellectual | 2012 |
The late phase skin reaction: paradigm or epiphenomena?
Topics: Adrenal Cortex Hormones; Animals; Arthus Reaction; Chemotaxis, Leukocyte; Dermatitis, Atopic; Diseas | 1983 |
[Clinical study of the preventive action of ketotifen in children with allergic diseases].
Topics: Asthma; Child; Child, Preschool; Dermatitis, Atopic; Eczema; Humans; Hypersensitivity; Infant; Ketot | 1983 |
[Pharmacologic treatment and atopic dermatitis].
Topics: Animals; Cromolyn Sodium; Dermatitis, Atopic; Eggs; Female; Humans; Infant; Ketotifen; Male; Milk | 1994 |
Treatment of atopic dermatitis in children: the importance of skin care and environmental control.
Topics: Administration, Topical; Anti-Allergic Agents; Anti-Inflammatory Agents; Baths; Bedding and Linens; | 1996 |
Effect of H1-antihistamines on histamine release from dispersed canine cutaneous mast cells.
Topics: Animals; Calcimycin; Cell Survival; Cetirizine; Concanavalin A; Dermatitis, Atopic; Dog Diseases; Do | 1997 |
[Effect of ketotifen fumarate for seizures in Lennox-Gastaut syndrome; a care report].
Topics: Administration, Oral; Anti-Allergic Agents; Child; Dermatitis, Atopic; Epilepsy, Absence; Humans; Ke | 1999 |
Eosinophil involvement in atopic dermatitis as reflected by elevated serum levels of eosinophil cationic protein.
Topics: Adolescent; Adult; Blood Proteins; Child; Dermatitis, Atopic; Eosinophil Granule Proteins; Eosinophi | 1992 |
[Manifestations of pseudo-allergy in different diseases in children].
Topics: Adjuvants, Immunologic; Adolescent; Angioedema; Child; Child, Preschool; Dermatitis, Atopic; Diagnos | 1990 |
Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma.
Topics: Adolescent; Allergens; Asthma; Child; Child, Preschool; Concanavalin A; Dermatitis, Atopic; Female; | 1990 |
Ketotifen treatment of atopic dermatitis and other food allergy diseases.
Topics: Adult; Child; Child, Preschool; Dermatitis, Atopic; Drug Administration Schedule; Food Hypersensitiv | 1989 |
[Atopic dermatitis. I. Characteristics of the clinical course and state of the immune status in relation to the initial level of serum IgE].
Topics: Adolescent; Adult; Dermatitis, Atopic; Female; Humans; Immunity, Cellular; Immunoglobulin E; Ketotif | 1989 |
[The use of zaditen in the combined treatment of allergic skin diseases in children].
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Combined Modality Therapy; Dermatitis, Atopic; | 1989 |
The role of pharmacologic agents in the prevention or treatment of allergic food disorders.
Topics: Administration, Oral; Adult; Aspirin; Beclomethasone; Child; Cromolyn Sodium; Dermatitis, Atopic; Fo | 1986 |
[Clinical effectiveness and prospects for using zaditen (ketotifen) in the therapy of allergic dermatoses].
Topics: Adolescent; Adult; Aged; Chronic Disease; Dermatitis, Atopic; Drug Evaluation; Eczema; Female; Human | 1987 |
The determination of pharmacokinetic parameters of ketotifen in steady state in young children.
Topics: Asthma; Biological Availability; Child, Preschool; Dermatitis, Atopic; Female; Humans; Ketotifen; Ki | 1986 |
[Efficacy of ketotifen on skin manifestations in children with egg allergy].
Topics: Child, Preschool; Dermatitis, Atopic; Eggs; Food Hypersensitivity; Humans; Immunoglobulin E; Infant; | 1985 |