Page last updated: 2024-10-30

ketotifen and Disease Exacerbation

ketotifen has been researched along with Disease Exacerbation in 4 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Research Excerpts

ExcerptRelevanceReference
"Of these, 29 (33%) had eosinophilic esophagitis (EoE), and 10 (11%) had eosinophilic gastritis, gastroenteritis or enterocolitis."1.62Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up. ( Arikan, C; Can, D; Doganay, L; Ozdogan, E, 2021)
"Atherosclerosis was produced in apolipoprotein E-deficient (Apoe(-/-)) mice with a Western diet."1.43Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice. ( Cheng, X; Fernandes, C; Huang, X; Levy, B; Liao, M; Libby, P; Liu, CL; Santos, MM; Shi, GP; Sukhova, GK; Wang, Y; Wu, G; Yang, C; Zhang, JY, 2016)
"Ketotifen treatment does not appear to prohibit or reverse the inflammatory process in the gastric mucosa in EGE, although long-term effects of steroids may be avoided."1.35Longstanding eosinophilic gastroenteritis of more than 20 years. ( Freeman, HJ, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ozdogan, E1
Doganay, L1
Can, D1
Arikan, C1
Liu, CL1
Wang, Y1
Liao, M1
Santos, MM1
Fernandes, C1
Sukhova, GK1
Zhang, JY1
Cheng, X1
Yang, C1
Huang, X1
Levy, B1
Libby, P1
Wu, G1
Shi, GP1
Freeman, HJ1
Kalia, N1
Brown, NJ1
Wood, RF1
Pockley, AG1

Other Studies

4 other studies available for ketotifen and Disease Exacerbation

ArticleYear
Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up.
    The American journal of gastroenterology, 2021, 01-01, Volume: 116, Issue:1

    Topics: Age Factors; Anti-Allergic Agents; Biliary Atresia; Budesonide; Child; Child, Preschool; Cholestasis

2021
Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice.
    Translational research : the journal of laboratory and clinical medicine, 2016, Volume: 171

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Budesonide; Chronic Disease; Disease Progression; Gluco

2016
Longstanding eosinophilic gastroenteritis of more than 20 years.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009, Volume: 23, Issue:9

    Topics: Adult; Disease Progression; Endoscopy, Digestive System; Eosinophilia; Eosinophils; Gastric Mucosa;

2009
Ketotifen abrogates local and systemic consequences of rat intestinal ischemia-reperfusion injury.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:7

    Topics: Administration, Oral; Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Heart Ra

2005