ketotifen has been researched along with Diarrhea in 4 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to investigate the clinical efficacy and safety of ketotifen for the treatment of irritable bowel syndrome with diarrhea (IBS-D)." | 9.34 | Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea. ( Gu, W; Wang, J; Wang, X; Wang, Y; Yang, J; Zhou, H, 2020) |
| "The aim of the study was to investigate the clinical efficacy and safety of ketotifen for the treatment of irritable bowel syndrome with diarrhea (IBS-D)." | 5.34 | Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea. ( Gu, W; Wang, J; Wang, X; Wang, Y; Yang, J; Zhou, H, 2020) |
| "Eosinophilic gastroenteritis is a rare condition of unknown etiology characterized by peripheral eosinophilia, eosinophilic infiltration of the gastrointestinal tract, and gastrointestinal symptomatology." | 1.29 | Eosinophilic gastroenteritis. ( Hodges, WG; Huggins, TL; Lee, EL; Lee, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Wang, Y | 1 |
| Zhou, H | 1 |
| Gu, W | 1 |
| Wang, X | 1 |
| Yang, J | 1 |
| Sherman, MA | 1 |
| Feng, BS | 1 |
| He, SH | 1 |
| Zheng, PY | 1 |
| Wu, L | 1 |
| Yang, PC | 1 |
| Lee, M | 1 |
| Hodges, WG | 1 |
| Huggins, TL | 1 |
| Lee, EL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Omalizumab in Eosinophilic Gastroenteritis[NCT00084097] | Phase 2 | 30 participants | Interventional | 2004-06-02 | Completed | ||
| Pilot Study of Omalizumab (Xolair) in Hyper IgE (Job's) Syndrome[NCT00260702] | Phase 1 | 1 participants (Actual) | Interventional | 2005-11-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ketotifen and Diarrhea
| Article | Year |
|---|---|
Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea.
Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Intestinal Mucosa; Irritable Bowel Syndrom | 2020 |
3 other studies available for ketotifen and Diarrhea
| Article | Year |
|---|---|
The role of mast cells in bacterial enteritis.
Topics: Animals; Cell Degranulation; Diarrhea; Dose-Response Relationship, Drug; Drug Synergism; Histamine H | 2007 |
Mast cells play a crucial role in Staphylococcus aureus peptidoglycan-induced diarrhea.
Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Animals; Blotting, Western; Cell Degranu | 2007 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |
Eosinophilic gastroenteritis.
Topics: Abdominal Pain; Adult; Aged; Anemia; Anti-Allergic Agents; Cromolyn Sodium; Diarrhea; Eosinophilia; | 1996 |