ketotifen has been researched along with Delayed Hypersensitivity in 5 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to determine whether treatment with ketotifen inhibits asthmatic reactions induced by toluene di-isocyanate (TDI), we studied six sensitized subjects with previously demonstrated dual or late asthmatic reaction after inhalation challenge with TDI." | 9.06 | Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects. ( Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L, 1989) |
| "In order to determine whether treatment with ketotifen inhibits asthmatic reactions induced by toluene di-isocyanate (TDI), we studied six sensitized subjects with previously demonstrated dual or late asthmatic reaction after inhalation challenge with TDI." | 5.06 | Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects. ( Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L, 1989) |
| " Airway eosinophilia in repeatedly antigen-exposed guinea pigs was suppressed by chronic administration of HQL-79 for 2 weeks." | 1.30 | Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models. ( Aritake, K; Hayashi, K; Hayashi, M; Hirotsu, I; Hizue, M; Kimura, Y; Matsushita, N; Mitsui, K; Nakajima, H; Takada, A; Tani, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeShazo, RD | 1 |
| Levinson, AI | 1 |
| Dvorak, HF | 1 |
| Matsushita, N | 1 |
| Hizue, M | 1 |
| Aritake, K | 1 |
| Hayashi, K | 1 |
| Takada, A | 1 |
| Mitsui, K | 1 |
| Hayashi, M | 1 |
| Hirotsu, I | 1 |
| Kimura, Y | 1 |
| Tani, T | 1 |
| Nakajima, H | 1 |
| Tossin, L | 1 |
| Chiesura-Corona, P | 1 |
| Fabbri, LM | 1 |
| De Marzo, N | 1 |
| Picotti, G | 1 |
| Crescioli, S | 1 |
| Mapp, CE | 1 |
| Moniaci, D | 1 |
| Mozzati, M | 1 |
| Albera, G | 1 |
| Parabita, SF | 1 |
| Re, G | 1 |
| Herrmann, P | 1 |
| Schreier, MH | 1 |
| Borel, JF | 1 |
| Feurer, C | 1 |
1 trial available for ketotifen and Delayed Hypersensitivity
| Article | Year |
|---|---|
Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects.
Topics: Asthma; Cyanates; Double-Blind Method; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; | 1989 |
4 other studies available for ketotifen and Delayed Hypersensitivity
| Article | Year |
|---|---|
The late phase skin reaction: paradigm or epiphenomena?
Topics: Adrenal Cortex Hormones; Animals; Arthus Reaction; Chemotaxis, Leukocyte; Dermatitis, Atopic; Diseas | 1983 |
Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens; Bronchoconstriction; Capillary Perme | 1998 |
[Pharmacologic prevention of allergic complications caused by local anesthesia in odontostomatology].
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Cromolyn Sodium; Drug Hypersensitivity; Histamine Antag | 1989 |
Mast cell degranulation as a major event in the effector phase of delayed-type hypersensitivity induced by cloned helper T cells.
Topics: Animals; Cell Movement; Clemastine; Clone Cells; Female; H-2 Antigens; Hypersensitivity, Delayed; Ke | 1988 |