Page last updated: 2024-10-30

ketotifen and Conjunctivitis

ketotifen has been researched along with Conjunctivitis in 7 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Conjunctivitis: INFLAMMATION of the CONJUNCTIVA.

Research Excerpts

ExcerptRelevanceReference
"The results of this study suggest that emedastine and ketotifen are not significantly different with respect to anti-itching efficacy in the CAC model of acute allergic conjunctivitis."5.10Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model. ( Bensch, G; D'Arienzo, PA; Leonardi, A, 2002)
"Olopatadine is more effective than ketotifen in reducing the itching associated with allergic conjunctivitis in the antigen challenge model."5.09A comparison of the relative efficacy and clinical performance of olopatadine hydrochloride 0.1% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the conjunctival antigen challenge model. ( Bensch, G; Berdy, GJ; Berdy, SS; Brusatti, RC; Spangler, DL, 2000)
"1% Ketotifen ophthalmic preparation was evaluated in 11 cases of conjunctivitis due to Japanese cedar pollinoisis (three cases also associated with vernal catarrh)."5.05Therapeutic effects of a new, anti-allergic ophthalmic preparation. ( Arai, Y; Fujiwara, T; Kubota, A; Mikuni, I; Mizushima, N; Mochida, H; Togawa, K, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dennis, M1
Maoz, A1
Hughes, D1
Sanchorawala, V1
Sloan, JM1
Sarosiek, S1
Blondin, C1
Cholley, B1
Haeffner-Cavaillon, N1
Goldschmidt, P1
Mikuni, I2
Sato, K1
Togawa, K2
Mizushima, N2
Fujiwara, T1
Mochida, H1
Arai, Y1
Kubota, A1
Mancel, E1
Drouet, M1
Sabbah, A1
Berdy, GJ1
Spangler, DL1
Bensch, G2
Berdy, SS1
Brusatti, RC1
D'Arienzo, PA1
Leonardi, A1

Reviews

1 review available for ketotifen and Conjunctivitis

ArticleYear
[Membrane stabilizers (chromones and ketotifen)].
    Allergie et immunologie, 1999, Volume: 31, Issue:4

    Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cell Membrane; Conjunctivitis; Cromoly

1999

Trials

3 trials available for ketotifen and Conjunctivitis

ArticleYear
Therapeutic effects of a new, anti-allergic ophthalmic preparation.
    The Tokai journal of experimental and clinical medicine, 1982, Volume: 7, Issue:2

    Topics: Animals; Clinical Trials as Topic; Conjunctivitis; Humans; Hypersensitivity; Ketotifen; Ointments; P

1982
A comparison of the relative efficacy and clinical performance of olopatadine hydrochloride 0.1% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the conjunctival antigen challenge model.
    Clinical therapeutics, 2000, Volume: 22, Issue:7

    Topics: Allergens; Anti-Allergic Agents; Antigens; Conjunctivitis; Dibenzoxepins; Double-Blind Method; Human

2000
Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model.
    Clinical therapeutics, 2002, Volume: 24, Issue:3

    Topics: Allergens; Anti-Allergic Agents; Benzimidazoles; Conjunctivitis; Double-Blind Method; Eye Color; Fem

2002

Other Studies

3 other studies available for ketotifen and Conjunctivitis

ArticleYear
Bortezomib ocular toxicities: Outcomes with ketotifen.
    American journal of hematology, 2019, Volume: 94, Issue:3

    Topics: Adult; Aged; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Chalazion; Con

2019
[In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter].
    Journal francais d'ophtalmologie, 2003, Volume: 26, Issue:4

    Topics: Air Pollutants; Anti-Allergic Agents; Benzalkonium Compounds; Benzimidazoles; Complement Activation;

2003
A quantitative tear fluids determination of therapeutic efficacy for allergic conjunctivitis.
    The Tokai journal of experimental and clinical medicine, 1984, Volume: 9, Issue:1

    Topics: Adult; Child; Conjunctivitis; Female; Humans; Ketotifen; Male; Refractometry; Rhinitis, Allergic, Se

1984