ketotifen has been researched along with Complication, Postoperative in 6 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to use a validated rabbit model to assess the effects on surgically-induced knee joint contractures of two combined pharmacological interventions: celecoxib (CXB) loaded on an implanted collagen membrane, and subcutaneously (SQ) injected ketotifen." | 3.96 | Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen. ( Abdel, MP; Berry, CE; Berry, DJ; Bolon, B; Carter, JM; Jay, AG; Limberg, AK; McLaury, AR; Morrey, ME; Salib, CG; Sanchez-Sotelo, J; Tibbo, ME; Turner, TW; van Wijnen, AJ, 2020) |
| "The therapeutic potential of long-term ketotifen in irritable bowel syndrome and postoperative ileus is currently under investigation." | 3.79 | Word of caution before implementing ketotifen for gastrointestinal transit improvement. ( de Haan, JJ; Reisinger, KW; Schreinemacher, MH, 2013) |
| "Of these, 29 (33%) had eosinophilic esophagitis (EoE), and 10 (11%) had eosinophilic gastritis, gastroenteritis or enterocolitis." | 1.62 | Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up. ( Arikan, C; Can, D; Doganay, L; Ozdogan, E, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, H | 1 |
| Yoneya, Y | 1 |
| Mikawa, S | 1 |
| Kaji, N | 1 |
| Ito, H | 1 |
| Tsuchida, Y | 1 |
| Komatsu, H | 1 |
| Murata, T | 1 |
| Ozaki, H | 1 |
| Uchida, R | 1 |
| Nishida, K | 1 |
| Hori, M | 1 |
| Limberg, AK | 1 |
| Tibbo, ME | 1 |
| Salib, CG | 1 |
| McLaury, AR | 1 |
| Turner, TW | 1 |
| Berry, CE | 1 |
| Jay, AG | 1 |
| Carter, JM | 1 |
| Bolon, B | 1 |
| Berry, DJ | 1 |
| Morrey, ME | 1 |
| Sanchez-Sotelo, J | 1 |
| van Wijnen, AJ | 1 |
| Abdel, MP | 1 |
| Ozdogan, E | 1 |
| Doganay, L | 1 |
| Can, D | 1 |
| Arikan, C | 1 |
| Reisinger, KW | 1 |
| de Haan, JJ | 1 |
| Schreinemacher, MH | 1 |
| Rychter, J | 1 |
| Ortega, O | 1 |
| Berdun, S | 1 |
| Arenas, C | 1 |
| Lopez, I | 1 |
| Espin, F | 1 |
| Vergara, P | 1 |
| Clavé, P | 1 |
| Coneely, J | 1 |
| Kennelly, R | 1 |
| Bouchier-Hayes, D | 1 |
| Winter, DC | 1 |
6 other studies available for ketotifen and Complication, Postoperative
| Article | Year |
|---|---|
A new zinc chelator, IPZ-010 ameliorates postoperative ileus.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, | 2020 |
Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen.
Topics: Animals; Celecoxib; Contracture; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Delivery | 2020 |
Disease Course and Treatment Response of Eosinophilic Gastrointestinal Diseases in Children With Liver Transplantation: Long-Term Follow-Up.
Topics: Age Factors; Anti-Allergic Agents; Biliary Atresia; Budesonide; Child; Child, Preschool; Cholestasis | 2021 |
Word of caution before implementing ketotifen for gastrointestinal transit improvement.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Transit; Ileus; Irrita | 2013 |
Mast cell degranulation inhibits motor patterns of human ileum and sigmoid colon in vitro: relevance for postoperative ileus.
Topics: Adult; Aged; Aged, 80 and over; Cell Degranulation; Colon, Sigmoid; Female; Humans; Ileum; Ileus; In | 2015 |
Mast cell degranulation is essential for anastomotic healing in well perfused and poorly perfused rat colon.
Topics: Anastomosis, Surgical; Angiography; Animals; Cell Degranulation; Colon; Histamine H1 Antagonists; Is | 2010 |