ketotifen has been researched along with Bronchospasm, Exercise-Induced in 22 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open clinical study, 80 children and adolescents of 12 months to 20 years of age suffering from asthma bronchiale were treated for a minimum of 8 weeks with DNCG (acecromol) or ketotifen (Zatofug) or with both drugs." | 9.07 | [DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma]. ( Kehnscherper, M, 1993) |
| "In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily." | 9.06 | Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults. ( Lim, TK; Tan, WC, 1987) |
| "The efficacy of ketotifen, a tricyclic benzocycloheptathiophene derivative, was assessed in an outpatient clinical trial and in a group of 12 asthmatic subjects with exercise-induced asthma." | 9.05 | Ketotifen in atopic asthma and exercise-induced asthma. ( Bierman, CW; McAllen, M; Moxham, J; Petheram, IS; Spiro, SG, 1981) |
| "2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG)." | 9.05 | Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys. ( Bevegård, S; Graff-Lonnevig, V; Lilja, G, 1983) |
| " In this study, we looked at the changes in the number of sanguineous cells that ketotifen produces, especially in basophil cells, that could explain its prophylactic effects in bronchial hyperreactivity disclosed by exercise, as well as its relation to the variations in basal and total histamine in blood." | 7.68 | In vitro ketotifen protection in bronchial hyperreactivity. ( Córdoba, H; Fernández, M; Oehling, A; Santos, F, 1991) |
| "In an open clinical study, 80 children and adolescents of 12 months to 20 years of age suffering from asthma bronchiale were treated for a minimum of 8 weeks with DNCG (acecromol) or ketotifen (Zatofug) or with both drugs." | 5.07 | [DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma]. ( Kehnscherper, M, 1993) |
| "In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily." | 5.06 | Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults. ( Lim, TK; Tan, WC, 1987) |
| "The efficacy of ketotifen, a tricyclic benzocycloheptathiophene derivative, was assessed in an outpatient clinical trial and in a group of 12 asthmatic subjects with exercise-induced asthma." | 5.05 | Ketotifen in atopic asthma and exercise-induced asthma. ( Bierman, CW; McAllen, M; Moxham, J; Petheram, IS; Spiro, SG, 1981) |
| "2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG)." | 5.05 | Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys. ( Bevegård, S; Graff-Lonnevig, V; Lilja, G, 1983) |
| " In this study, we looked at the changes in the number of sanguineous cells that ketotifen produces, especially in basophil cells, that could explain its prophylactic effects in bronchial hyperreactivity disclosed by exercise, as well as its relation to the variations in basal and total histamine in blood." | 3.68 | In vitro ketotifen protection in bronchial hyperreactivity. ( Córdoba, H; Fernández, M; Oehling, A; Santos, F, 1991) |
| " Certain drugs such as antihistamines and ketotifen may be more effective administered by inhalation since high concentrations with reduced unwanted effects can be achieved on the bronchial surface where, in allergic asthma, the critical initial interaction between sensitized mast cells (mucosal?) and allergen with subsequent mediator release occurs." | 3.67 | Use of inhaled calcium channel blocking agents in the treatment of asthma. ( Bennett, J; Davies, RJ; Osman, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (86.36) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petheram, IS | 1 |
| Moxham, J | 1 |
| Bierman, CW | 1 |
| McAllen, M | 1 |
| Spiro, SG | 1 |
| Furukawa, CT | 1 |
| Dorward, AJ | 2 |
| Patel, KR | 2 |
| Debelic, M | 2 |
| Lilja, G | 1 |
| Graff-Lonnevig, V | 1 |
| Bevegård, S | 1 |
| Davies, RJ | 1 |
| Bennett, J | 1 |
| Osman, J | 1 |
| Kennedy, JD | 1 |
| Hasham, F | 1 |
| Clay, MJ | 1 |
| Jones, RS | 1 |
| Cameron, E | 1 |
| Tanser, AR | 1 |
| Elmes, J | 1 |
| Stemmann, EA | 1 |
| Weihermann, D | 1 |
| Schachoff, R | 1 |
| Warner, JO | 1 |
| Goldsworthy, SJ | 1 |
| Nagai, H | 1 |
| Iwama, T | 1 |
| Mori, H | 1 |
| Nishida, H | 1 |
| Takatsu, K | 1 |
| Iikura, Y | 1 |
| Kehnscherper, M | 1 |
| Fernández, M | 1 |
| Córdoba, H | 1 |
| Santos, F | 1 |
| Oehling, A | 1 |
| Wagner, W | 1 |
| Tan, WC | 1 |
| Lim, TK | 1 |
| Al Frayh, A | 1 |
| Delnitz, D | 1 |
| Rozniecki, J | 1 |
| Grabski, W | 1 |
| Nagy, L | 1 |
| Orosz, M | 1 |
| Wasek, Z | 1 |
| Malinowski, R | 1 |
| Frank-Piskorska, A | 1 |
1 review available for ketotifen and Bronchospasm, Exercise-Induced
| Article | Year |
|---|---|
Ketotifen in childhood allergic disease.
Topics: Aging; Airway Obstruction; Animals; Asthma; Asthma, Exercise-Induced; Body Weight; Bronchial Provoca | 1982 |
10 trials available for ketotifen and Bronchospasm, Exercise-Induced
| Article | Year |
|---|---|
Ketotifen in atopic asthma and exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Double-Blind M | 1981 |
A comparison of ketotifen with clemastine, ipratropium bromide and sodium cromoglycate in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Atropine Derivatives; Child; Clemastine; Cromol | 1982 |
Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Double-Blind Method; Humans; Ketotife | 1983 |
A controlled trial of ketotifen in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Doub | 1980 |
[Prophylactic treatment of exercise-induced asthma].
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Child; Child, Preschool; Cromol | 1981 |
Ketotifen in childhood allergic disease.
Topics: Aging; Airway Obstruction; Animals; Asthma; Asthma, Exercise-Induced; Body Weight; Bronchial Provoca | 1982 |
[DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma].
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Airway Resistance; Asthma; Asth | 1993 |
Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Double-Blind Method; Female; F | 1987 |
[Comparative evaluation of the effects of sodium cromoglycate and ketotifen on exercise-induced bronchospasm in patients with asthma].
Topics: Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Female; Humans; | 1985 |
Effect of Zaditen on serum neutrophil chemotactic activity in exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Humans; Ketotifen; Neutrophils; Premed | 1985 |
12 other studies available for ketotifen and Bronchospasm, Exercise-Induced
| Article | Year |
|---|---|
Other pharmacologic agents that may affect bronchial hyperreactivity.
Topics: Adrenergic alpha-Antagonists; Asthma; Asthma, Exercise-Induced; Benzothiazoles; Budesonide; Calcium | 1984 |
[Clinico-experimental possibilities in asthma].
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Cromolyn Sodium; Drug Evaluation; Hum | 1984 |
Use of inhaled calcium channel blocking agents in the treatment of asthma.
Topics: Aerosols; Airway Resistance; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Test | 1984 |
Comparison of actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction in childhood asthma.
Topics: Asthma; Asthma, Exercise-Induced; Child; Cromolyn Sodium; Humans; Ketotifen; Piperidines; Thiophenes | 1980 |
Actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction.
Topics: Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Humans; Ketotifen; Piperidines; Thiophenes | 1981 |
Pharmacological rehabilitation of the asthmatic child.
Topics: Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Child; Cromolyn Sodium; Huma | 1981 |
Increase in respiratory resistance after exercise in conscious guinea pigs. As a model for exercise-induced asthma.
Topics: Airway Resistance; Animals; Asthma, Exercise-Induced; Bronchoalveolar Lavage Fluid; Disease Models, | 1995 |
In vitro ketotifen protection in bronchial hyperreactivity.
Topics: Adolescent; Adult; Animals; Asthma, Exercise-Induced; Basophil Degranulation Test; Basophils; Bronch | 1991 |
Exercise-induced allergic syndromes on the increase.
Topics: Adolescent; Adult; Albuterol; Anaphylaxis; Asthma; Asthma, Exercise-Induced; Beclomethasone; Exercis | 1989 |
The prophylactic benefits of twice-daily ketotifen in asthmatic Saudi children.
Topics: Asthma; Asthma, Exercise-Induced; Child; Drug Administration Schedule; Female; Humans; Ketotifen; Ma | 1986 |
[Effect of Zaditen on the clinical status and ventilatory parameters in patients with various types of bronchial asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Humans; Ketotifen; Middl | 1985 |
Inhaled ketotifen in exercise-induced asthma--a negative report.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Humans; Ketot | 1985 |