ketotifen has been researched along with Breathing Sounds in 10 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 9.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study." | 9.07 | A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992) |
| "Ketotifen is an antihistamine which may be used to treat asthma." | 8.82 | Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. ( Bassler, D; Ducharme, FM; Forster, J; Mitra, A; Schwarzer, G, 2004) |
| "Ketotifen was not associated with any adverse effects and did not cause behavioural problems." | 6.66 | Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma. ( el Beshlawy, A; el Hefny, A; Nour, S; Said, M, 1986) |
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 5.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study." | 5.07 | A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992) |
| "Ketotifen is an antihistamine which may be used to treat asthma." | 4.82 | Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. ( Bassler, D; Ducharme, FM; Forster, J; Mitra, A; Schwarzer, G, 2004) |
| "The ketotifen dosage was 0." | 2.67 | Multicenter study with ketotifen (Zaditen) oral drop solution in the treatment of wheezy children aged 6 months to 3 years. ( Rotchild, M; Schlessinger, M; Soferman, R; Tabachnik, E; Tal, A; Varsano, I; Volovitz, B, 1993) |
| "Ketotifen was not associated with any adverse effects and did not cause behavioural problems." | 2.66 | Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma. ( el Beshlawy, A; el Hefny, A; Nour, S; Said, M, 1986) |
| "Ketotifen was well-tolerated by the majority of patients." | 2.65 | Treatment of wheezy infants and children with ketotifen. ( El-Hefny, A, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshihara, S | 1 |
| Ono, M | 1 |
| Yamada, Y | 1 |
| Fukuda, H | 1 |
| Abe, T | 1 |
| Arisaka, O | 1 |
| Ngamphaiboon, J | 1 |
| Wirawarn, T | 1 |
| Thongkaew, T | 1 |
| Schwarzer, G | 1 |
| Bassler, D | 1 |
| Mitra, A | 1 |
| Ducharme, FM | 1 |
| Forster, J | 1 |
| Kaditis, AG | 1 |
| Winnie, G | 1 |
| Syrogiannopoulos, GA | 1 |
| El-Hefny, A | 1 |
| Varsano, I | 1 |
| Volovitz, B | 1 |
| Soferman, R | 1 |
| Tal, A | 1 |
| Schlessinger, M | 1 |
| Rotchild, M | 1 |
| Tabachnik, E | 1 |
| Kabra, SK | 1 |
| Pandey, RM | 1 |
| Singh, R | 1 |
| Seth, V | 1 |
| Chay, OM | 1 |
| Foo, AL | 1 |
| Ho, L | 1 |
| van Asperen, PP | 1 |
| McKay, KO | 1 |
| Mellis, CM | 1 |
| Loh, RK | 1 |
| Harth, SC | 1 |
| Thong, YH | 1 |
| Harris, M | 1 |
| Robertson, IF | 1 |
| Gibbeson, M | 1 |
| Rhodes, L | 1 |
| el Hefny, A | 1 |
| el Beshlawy, A | 1 |
| Nour, S | 1 |
| Said, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Inhaled Corticosteroids in Preschool Children Following Hospital Admission for Acute Dyspnea and Wheeze[NCT00962299] | Phase 4 | 7 participants (Actual) | Interventional | 2010-05-31 | Terminated (stopped due to recruitment was unsuccesfull, only 7 patient have been included untill 2012) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ketotifen and Breathing Sounds
| Article | Year |
|---|---|
Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children.
Topics: Anti-Asthmatic Agents; Asthma; Child; Histamine H1 Antagonists; Humans; Ketotifen; Randomized Contro | 2004 |
Anti-inflammatory pharmacotherapy for wheezing in preschool children.
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cetirizine; Chi | 2007 |
8 trials available for ketotifen and Breathing Sounds
| Article | Year |
|---|---|
Early intervention with suplatast tosilate for prophylaxis of pediatric atopic asthma: a pilot study.
Topics: Allergens; Animals; Anti-Allergic Agents; Arylsulfonates; Asthma; Chemoprevention; Dermatitis, Atopi | 2009 |
Prevention of recurrent wheezing in young children by loratadine compared with ketotifen.
Topics: Administration, Oral; Anti-Allergic Agents; Asthma; Child, Preschool; Double-Blind Method; Female; H | 2009 |
Treatment of wheezy infants and children with ketotifen.
Topics: Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Ketotifen; Male; Respiratory Sou | 1983 |
Multicenter study with ketotifen (Zaditen) oral drop solution in the treatment of wheezy children aged 6 months to 3 years.
Topics: Asthma; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Ketotifen; | 1993 |
Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial.
Topics: Adolescent; Anti-Allergic Agents; Asthma; Child; Child, Preschool; Cough; Dose-Response Relationship | 2000 |
Efficacy of Zaditen (ketotifen) in wheezy infants and young children.
Topics: Child, Preschool; Double-Blind Method; Humans; Infant; Ketotifen; Respiratory Sounds | 1992 |
A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze.
Topics: Child, Preschool; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Infant; Ketotifen; Ma | 1992 |
Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma.
Topics: Asthma; Bronchitis; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Ketotifen; Respirato | 1986 |