ketotifen has been researched along with Asthma in 329 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic efficacy of ketotifen in the prophylactic treatment of asthmatic children and adolescents is reviewed, based on the results from 4 double-blind placebo-controlled trials involving 194 patients, 2 double-blind clemastine-controlled trials involving 86 patients, and 5 double-blind double-dummy comparative studies with disodium cromoglycate involving 136 patients." | 10.15 | Prophylaxis of asthma with ketotifen in children and adolescents: a review. ( Craps, L, 1983) |
| "To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)." | 9.30 | [Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019) |
| "To compare the efficacy and safety of ketotifen and inhaled budesonide in asthmatic children aged 8 months to 14 years at Banpong Hospital, located 80 km south from Bangkok." | 9.14 | Ketotifen versus inhaled budesonide for controlling childhood asthma. ( Preutthipan, A; Tantichaiyakul, P, 2010) |
| "Montelukast and ketotifen are oral anti-allergy medications in asthmatic children." | 9.12 | Regulation of stromal cell-derived factor-1 and exhaled nitric oxide in asthmatic children following montelukast and ketotifen treatment. ( Chang, HC; Hua, YM; Hung, CH; Jong, YJ; Lai, YS; Li, CY; Yang, KD, 2007) |
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 9.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "In view of the possible systemic side-effects of inhaled corticosteroids (ICS), a study was performed to determine whether ketotifen (versus placebo) can replace or allow a reduction in the dose of ICS required for the maintenance treatment of childhood asthma." | 9.08 | Does ketotifen have a steroid-sparing effect in childhood asthma? ( Canny, GJ; Levison, H; Reisman, J, 1997) |
| "Administration of theophylline to asthmatic children is frequently associated with an adverse influence on their behavior." | 9.07 | Administration of half-dose theophylline together with ketotifen to asthmatic children--a double-blind, placebo-controlled study. ( Amir, J; Lerman, M; Malik, H; Varsano, I; Volovitz, B, 1994) |
| "Effects of ultrasonically nebulized distilled water (UNDW) on PtcO2 and PtcCO2 time courses were studied in 26 mild asthmatics (FEV1 non-responders) in basal conditions and monitored after 2, 6, 12 and 18 weeks of randomly allocated treatment with ketotifen 1 mg b." | 9.07 | Transcutaneous O2 and CO2 monitoring of bronchial responsiveness in FEV1 non-responder asthmatics during ketotifen and placebo treatment. ( Allegra, L; Dal Negro, R; Pomari, C; Turco, P, 1993) |
| "In an open clinical study, 80 children and adolescents of 12 months to 20 years of age suffering from asthma bronchiale were treated for a minimum of 8 weeks with DNCG (acecromol) or ketotifen (Zatofug) or with both drugs." | 9.07 | [DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma]. ( Kehnscherper, M, 1993) |
| "Ninety-six patients with nocturnal asthma (FEV1 = 60-90% pred, reversibility greater than or equal to 15%, at least 2 awakenings in the week preceding the trial) were included in a double-blind, randomized, crossover, multicenter study which compared the efficacy and side effects of inhaled salmeterol (50 micrograms morning and evening) to the association theophylline-ketotifen (300 mg and 1 mg morning and evening, respectively)." | 9.07 | [Usefulness of salmeterol in nocturnal asthma: a comparative study with theophylline-ketotifen association. A French multicenter group]. ( Georges, D; Muir, JF, 1992) |
| "To evaluate the prophylactic effect of ketotifen against the onset of asthma we selected 121 infants with atopic dermatitis, without any history suggestive of asthma (cough and/or wheezing)." | 9.07 | Prevention of asthma by ketotifen in infants with atopic dermatitis. ( Baba, M; Iikura, Y; Mikawa, H; Naspitz, CK; Nishima, S; Sole, D; Talaricoficho, S, 1992) |
| "Ketotifen, an antianaphylactic and antihistamine drug was given orally to 31 asthma patients who had significant airflow limitation (mean FEV1% FVC = 65." | 9.06 | Pulmonary function parameters in asthma patients receiving oral ketotifen. ( Maselle, AY; Mashalla, YJ, 1990) |
| "Ketotifen was administered orally, for 3 months, to 40 children aged 3-14 years with chronic extrinsic asthma of moderate severity in a double-blind placebo-controlled study." | 9.06 | Effect of ketotifen on childhood asthma: a double-blind study. ( Anagnostakis, I; Hadziargurou, D; Liapi-Adamidou, G; Mylona-Karayanni, C; Saxoni-Papageorgiou, F; Sinaniotis, C, 1990) |
| "In order to determine whether treatment with ketotifen inhibits asthmatic reactions induced by toluene di-isocyanate (TDI), we studied six sensitized subjects with previously demonstrated dual or late asthmatic reaction after inhalation challenge with TDI." | 9.06 | Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects. ( Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L, 1989) |
| "The efficacy and tolerability of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin dihydrochloride) (2 mg twice daily orally) in comparison with ketotifen (1 mg twice daily orally) was investigated in 400 patients with bronchial asthma (picumast dihydrochloride n = 202, ketotifen n = 198) in a double-blind, controlled, parallel group study." | 9.06 | A one-year double-blind clinical study of the efficacy and tolerability of picumast dihydrochloride versus ketotifen in patients with bronchial asthma. ( Boerner, D; Müller, S; Slapke, J, 1989) |
| "Sixty children aged 5-13 years with moderately severe asthma took part in a double-blind, placebo-controlled trial of ketotifen." | 9.06 | Ketotifen in asthma. ( Dawson, KP; Fergusson, DM; Horwood, LJ; Mogridge, N, 1989) |
| "In a parallel, double-blind, placebo-controlled study we investigated the effect of the antiallergic drug Ketotifen on bronchial resistance (determined body plethysmographically) and beta 2-adrenoceptor density of lymphocytes (determined by 125-iodo-cyano-pindolol binding) in asthmatic children suffering from exercise-induced asthma (EIA)." | 9.06 | Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma. ( Braun, D; Griese, M; Kusenbach, G; Ludwig, J; Reinhardt, D, 1988) |
| "In order to examine a possible mechanism of action of ketotifen in asthma, a double-blind study was undertaken to determine whether ketotifen showed any effects on the beta-adrenergic system in asthmatic patients." | 9.06 | The effects of ketotifen on beta-adrenergic activity in asthmatics. ( Burge, PS; Gove, RI; Skinner, C; Stableforth, DE, 1988) |
| "In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily." | 9.06 | Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults. ( Lim, TK; Tan, WC, 1987) |
| "Thirty children (aged 1 to 3 years) with mild to moderate asthma were entered into a 28-week double-blind, crossover study comparing the prophylactic effect of ketotifen and placebo." | 9.06 | Efficacy and safety of ketotifen in young children with asthma. ( Cumella, JC; Jaber, L; Varsano, I; Volovitz, B, 1988) |
| "Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH)." | 9.06 | Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation? ( Biggs, BA; Ferguson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1987) |
| "The place of KETOTIFEN in the immunotherapy for atopic asthmatic patients (confirmed by cutaneous test and RAST) has been determined by a study conducted on 48 patients divided into two randomly selected parallel groups." | 9.06 | [Role of ketotifen in the immunotherapy of atopic asthmatics]. ( Haddad, G; Pacaud, D; Papeix, P; Steeg, LF; Tran, Q; Vincent, J, 1986) |
| "This double-blind parallel group study evaluated ketotifen 1 mg bid versus placebo in the treatment of 30 adult seasonally allergic asthmatics during the course of the spring pollen season." | 9.06 | The use of ketotifen in the prophylaxis of seasonal allergic asthma. ( Carroll, MS; Lotner, GZ; Spangler, DL; Tinkelman, DG; Vanderpool, GE; Webb, CS, 1986) |
| "5 years were studied with respect to the protective effect of ketotifen on pollen-induced bronchial asthma." | 9.06 | Ketotifen in pollen-induced asthma: a double blind placebo-controlled study. ( Broberger, U; Graff-Lonnevig, V; Lilja, G; Rylander, E, 1986) |
| "Forty-seven children with chronic asthma, aged 2 to 6 years, completed a double-blind, placebo-controlled, crossover trial of ketotifen, 1 mg twice daily, in the prophylaxis of asthma." | 9.06 | Long-term, placebo-controlled trial of ketotifen in the management of preschool children with asthma. ( Loftus, BG; Price, JF, 1987) |
| "The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study." | 9.05 | Ketotifen in adult asthma. ( Dyson, AJ; Mackay, AD, 1980) |
| "The results of clinical trials in patients with allergic bronchial asthma performed to demonstrate the therapeutic effect of the newly developed substance Ketotifen are reviewed: 1." | 9.05 | [Long-term therapy of bronchial asthma with ketotifen. European experiences]. ( Magnussen, H, 1980) |
| "A randomized multicentre trial was done to investigate the protective effects of ketotifen and disodium cromoglycate (DSCG) in the therapy of bronchial asthma." | 9.05 | [Treatment of seasonal asthmatic symptoms. A multicentre trial to compare the effects of ketotifen and disodium cromoglycate (author's transl)]. ( Borelli, S; Düngemann, H; Schiess, W, 1980) |
| "1 Ketotifen (HC 20-511 Sandoz) 1 mg twice daily for 12 weeks was found to be equivalent to sodium cromoglycate (SCG) 20 mg four times daily for 12 weeks in 35 skin test positive asthmatic patients in a randomised double-blind cross-over study." | 9.05 | A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma. ( Clarke, CW; May, CS, 1980) |
| "The efficacy of ketotifen, a tricyclic benzocycloheptathiophene derivative, was assessed in an outpatient clinical trial and in a group of 12 asthmatic subjects with exercise-induced asthma." | 9.05 | Ketotifen in atopic asthma and exercise-induced asthma. ( Bierman, CW; McAllen, M; Moxham, J; Petheram, IS; Spiro, SG, 1981) |
| "Ketotifen, an orally active, prophylactic anti-asthmatic drug, was compared with placebo in a double-blind, three-month parallel-group trial in 20 children." | 9.05 | Ketotifen: a new drug for prophylaxis of asthma in children. ( Becker, AB; Gillespie, CA; Luciuk, GH; Simons, FE, 1982) |
| "A double blind crossover comparison of slow-release theophylline, ketotifen and placebo was carried out in 18 young children with perennial asthma." | 9.05 | A controlled comparison of slow-release theophylline, ketotifen and placebo in the prophylaxis of asthma in young children. ( Carswell, F; Fysh, WJ; Hughes, AO; Robinson, P; Stratton, D, 1983) |
| "Report on a double-blind parallel group comparison of ketotifen and placebo in two groups of twenty-five children with extrinsic bronchial asthma." | 9.05 | The prophylactic treatment of bronchial asthma in children with ketotifen: a double-blind comparison with placebo. ( Spicak, V, 1983) |
| "Clinical trials of slow-release theophylline and ketotifen as prophylaxis against asthma in 18 young children suggested that both drugs had some efficacy." | 9.05 | Double-blind comparisons of slow-release theophylline, ketotifen and placebo for prophylaxis of asthma in young children. ( Carswell, F; Fysh, WJ; Hughes, AO; Robinson, P; Stratton, D, 1984) |
| "2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG)." | 9.05 | Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys. ( Bevegård, S; Graff-Lonnevig, V; Lilja, G, 1983) |
| "The therapeutic effects of inhaled disodium cromoglycate (DSCG) and orally administered ketotifen were compared in thirty atopic asthmatics aged 15-34 years during a 22-week double-blind parallel group study." | 9.05 | A double-blind comparison of ketotifen and disodium cromoglycate in atopic adult asthmatics. ( Sears, MR, 1983) |
| "Thirty-six children with verified deciduous tree pollen-induced asthma were studied with respect to the prophylactic effect and tolerance of ketotifen, in comparison to disodium cromoglycate." | 9.05 | A comparative study of the prophylactic effect of ketotifen and sodium cromoglycate in children with pollen-induced asthma. ( Graff-Lonnevig, V; Kusoffsky, E, 1980) |
| "The protective effect of ketotifen was examined by an open assessment trial in 261 asthmatics of variable types, a double blind trial comparing ketotifen and inert placebo in 189 asthmatics of extrinsic type including pure atopic asthma and asthma with atopic and infectious components (mixed type or combined type), and a double blind trial comparing ketotifen and disodium cromoglycate (DSCG) by double placebo technique in 132 asthmatics of a pure atopic type." | 9.05 | Clinical evaluation of a new orally active anti-anaphylactic compound: ketotifen (HC 20-511) in Japanese adult asthmatics. ( Kumagai, A; Muranaka, M; Shida, T; Takahashi, T; Tomioka, H, 1980) |
| "Sixty-four patients with mild of moderate extrinsic asthma were treated with placebo for 1 month and thereafter with ketotifen (1 mg twice daily, orally), disodium cromoglycate (inhalation of 20 mg, four times daily), or placebo for 2 subsequent months." | 9.05 | Comparison of ketotifen, disodium cromoglycate and placebo in the treatment of adult patients with mild extrinsic asthma. ( Ahonen, A; Haahtela, T; Hurme, R; Maasilta, P; Mattson, K; Muittari, A; Poppius, H; Venho, K, 1981) |
| "A double-blind non crossover trial comparing disodium cromoglycate (DSCG), with ketotifen, was carried out in twenty-seven extrinsic asthmatic children over 12 weeks." | 9.05 | A double-blind trial comparing disodium cromoglycate (DSCG), and ketotifen in extrinsic asthmatic children. ( Holgado de Cuesta, D; Schuhl, JF, 1981) |
| "Plasma histamine and serum neutrophil chemotactic activity (S-NCA) were measured in ten atopic asthmatic patients on four separate occasions after allergen bronchial provocation testing (BPT)." | 9.05 | Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds. ( Cundell, DR; Davies, RJ; Moodley, I; Morgan, DJ; Sheinman, BD; Smart, W, 1985) |
| "This study was designed to assess the acute effect of 1 mg of orally administered ketotifen on the dose-response curve to both histamine and methacholine, in 15 patients with bronchial asthma." | 9.05 | Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma. ( Barja, S; Cruz, E; Ferretti, R; Lisboa, C; Moran, J; Moreno, R; Sanchez, I, 1985) |
| "Three hundred seventy-four patients with asthma were entered into a year-long, double-blind, double-placebo controlled study comparing the prophylactic effect of ketotifen (229 patients), theophylline (73 patients), and placebo (72 patients)." | 9.05 | A multicenter trial of the prophylactic effect of ketotifen, theophylline, and placebo in atopic asthma. ( Buckley, CE; Bukantz, SC; Chodosh, S; Cohen, BM; Dobken, JH; Moss, BA; Rappaport, I; Rosenthal, RR; Sheffer, AL; Tinkelman, DG, 1985) |
| "12 patients with bronchial asthma received treatment with Ketotifen for three months." | 9.04 | [Ketotifen, a new prophylactic agent in asthma (author's transl)]. ( Fryda-Kaurimsky, Z; Giesen, HK, 1979) |
| "Ketotifen is an antihistamine which may be used to treat asthma." | 8.82 | Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. ( Bassler, D; Ducharme, FM; Forster, J; Mitra, A; Schwarzer, G, 2004) |
| "Ketotifen is an orally active prophylactic agent for the management of bronchial asthma and allergic disorders." | 8.78 | Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. ( Fitton, A; Goa, KL; Grant, SM; Sorkin, EM, 1990) |
| "The experimental data providing the rationale for the use of ketotifen as a prophylactic drug in asthma (inhibition of release of the mediators of anaphylaxis, particularly SRS-A, prevention of the bronchospasm induced by SRS-A in vivo, calcium antagonist effect) are briefly discussed, and the results of experimental and therapeutic trials carried out over 6 years in a number of countries in several thousand patients are reviewed." | 8.76 | Ketotifen in the oral prophylaxis of bronchial asthma: a review. ( Craps, L, 1981) |
| "Montelukast and ketotifen are commonly prescribed anti-inflammatory medications used in the treatment of childhood asthma." | 7.74 | Suppression of plasma matrix metalloproteinase-9 following montelukast treatment in childhood asthma. ( Chuang, SS; Hsu, SH; Hua, YM; Hung, CH; Jong, YJ; Lin, CS; Tien, CH; Yang, KD, 2007) |
| "The aim of the study was to evaluate the effect of ketotifen, nedocromil sodium and budesonide on non-specific bronchial hyperreactivity in asthmatic patients." | 7.68 | [Effect of ketotifen, nedocromil sodium and budesonide on non-specific bronchial hyperreactivity to histamine in patients with asthma]. ( Kazberuk, M; Rogalewska, A; Rutkowski, R; Siergiejko, Z, 1992) |
| "We tested the effect of Ketotifen (4-(1-methyl-4-piperidylidene)-4H- benzo[4,5] cyclohepta[1,2-b]thiophen-10(9H)-one hydrogen (fumarate) on the induction of allergen-induced IL-2 responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma." | 7.68 | Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma. ( Akasaka, T; Baba, M; Maeda, K; Noma, T; Yata, J; Yoshizawa, I, 1990) |
| "The inhibition of immediate allergen or histamine induced airflow obstruction by inhaled ketotifen, clemastine, sodium cromoglycate, and placebo was studied in two groups of asthmatic subjects." | 7.67 | Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma. ( Davies, RJ; Gould, C; Ollier, S; Phillips, MJ, 1984) |
| "Ten patients with allergic asthma were studied to compare the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses, especially the late asthmatic response, induced by house dust allergen in bronchial provocation tests." | 7.67 | A comparison of the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses to house dust, with special reference to the late asthmatic response. ( Adachi, M; Aoki, N; Furuya, A; Iijima, M; Kobayashi, H; Kokubu, F; Takahashi, T, 1984) |
| "An open pilot study was carried out over a period of more than 2 years to assess the steroid-sparing effect of ketotifen (1 mg twice daily) in 12 steroid-dependent asthmatic patients." | 7.67 | Steroid-sparing effect of ketotifen in steroid-dependent asthmatics: a long period evaluation in 12 patients. ( Izumi, S; Kasuya, S, 1988) |
| "In 13 patients with bronchial asthma, who were on beta 2-adrenergic bronchodilator therapy, the effects of prednisolone and ketotifen on lymphocyte beta 2-adrenoceptor density and -responsiveness were investigated." | 7.67 | Effect of prednisolone and ketotifen on beta 2-adrenoceptors in asthmatic patients receiving beta 2-bronchodilators. ( Brodde, OE; Egerszegi, S; Howe, U; Konietzko, N; Michel, MC, 1988) |
| "This study was undertaken to investigate the effect of ketotifen on the immune system of asthmatic children receiving prophylactic treatment with ketotifen." | 7.67 | Cellular immunity and suppressor T cell function in asthmatic children on prolonged ketotifen therapy. ( Armoni, M; Bibi, H; Fink, A; Schlesinger, M; Schwartz, Y; Shapira, H; Tabachnik, E, 1988) |
| "The results obtained with Ketotifen in 36 asthmatic children followed up during 12 months in the paediatrics department of the University Clinic of Kinshasa are reported." | 7.67 | [Clinical results of the treatment with ketotifen in asthmatic children in Zaire. Apropos of 36 cases followed at university clinics in Kinshasa (Zaire)]. ( Disengomoka-Muamba, I; Kanku, T, 1987) |
| "Alterations of the entire immunity profile of bronchial asthma patients have been studied following a half-year long Ketotifen treatment." | 7.67 | Ketotifen action upon the immunity state in bronchial asthma. ( Zavázal, V, 1985) |
| "Sixty-four patients with confirmed bronchial asthma were treated with HC 20-511 (Ketotifen)." | 7.66 | Clinical effects of HC 20-511 (ketotifen) in bronchial asthma and its inhibitory effect on antigen-induced morphological changes of basophils. ( Goda, Y; Harada, H; Kimura, I; Sasaki, Y; Takahashi, K; Tanizaki, Y, 1980) |
| "In a multicentre, double-blind trial, the steroid sparing effect of a new anti-anaphylactic agent ketotifen was assessed against placebo in eighty-six steroid-dependent asthmatics." | 7.66 | A steroid sparing effect of ketotifen in steroid-dependent asthmatics. ( Lane, DJ, 1980) |
| "The pharmacodynamic effects of ketotifen, a benzocycloheptathiophene derivative, on several partly interdependent biological pathways (calcium fluxes in excitable cells, production and release of mediators, mainly SRS-A, smooth-muscle contractility, density and sensitivity of adrenergic receptors) may be relevant to its antianaphylactic and asthma-prophylactic properties." | 7.66 | Ketotifen in the prophylaxis of bronchial asthma. ( Craps, L, 1982) |
| "23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules." | 7.66 | [Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980) |
| "Published pharmacokinetic data on ketotifen are sparse, although it is a commonly used prophylactic agent in various allergic disorders in adults and children." | 6.68 | Ketotifen pharmacokinetics in children with atopic perennial asthma. ( Ludden, TM; McFadyen, ML; Miller, R, 1997) |
| " Of the patients who were unable to stop taking theophylline, the Zaditen-and placebo-treated groups recorded average dosage reductions of 62% and 26%, respectively." | 6.66 | A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years. ( Brown, CA; Chandra, RK; Ho, P; Hoogerwerf, PE; Kennedy, RJ; Knight, A; Langer, H; Milne, J; Moote, DW; Rackham, A, 1989) |
| "In 12 patients with bronchial asthma we performed histamine bronchial challenges before and four hours after ingestion of placebo, 2." | 6.66 | The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients. ( Magnussen, H, 1987) |
| "Ketotifen was not associated with any adverse effects and did not cause behavioural problems." | 6.66 | Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma. ( el Beshlawy, A; el Hefny, A; Nour, S; Said, M, 1986) |
| "Eighteen children with perennial bronchial asthma with an average age of 9." | 6.66 | The effect of ketotifen on bronchial hyperreactivity in childhood asthma. ( Graff-Lonnevig, V; Hedlin, G, 1985) |
| "The therapeutic efficacy of ketotifen in the prophylactic treatment of asthmatic children and adolescents is reviewed, based on the results from 4 double-blind placebo-controlled trials involving 194 patients, 2 double-blind clemastine-controlled trials involving 86 patients, and 5 double-blind double-dummy comparative studies with disodium cromoglycate involving 136 patients." | 6.15 | Prophylaxis of asthma with ketotifen in children and adolescents: a review. ( Craps, L, 1983) |
| "To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)." | 5.30 | [Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019) |
| "It is clear that bronchial asthma is caused by chronic airway inflammation." | 5.29 | [The effect of ketotifen on the inflammation of bronchial mucosa in atopic asthmatics]. ( Hoshino, M, 1994) |
| "To compare the efficacy and safety of ketotifen and inhaled budesonide in asthmatic children aged 8 months to 14 years at Banpong Hospital, located 80 km south from Bangkok." | 5.14 | Ketotifen versus inhaled budesonide for controlling childhood asthma. ( Preutthipan, A; Tantichaiyakul, P, 2010) |
| "Montelukast and ketotifen are oral anti-allergy medications in asthmatic children." | 5.12 | Regulation of stromal cell-derived factor-1 and exhaled nitric oxide in asthmatic children following montelukast and ketotifen treatment. ( Chang, HC; Hua, YM; Hung, CH; Jong, YJ; Lai, YS; Li, CY; Yang, KD, 2007) |
| "In a randomized study, two oral medications, ketotifen and montelukast, were compared for children with mild persistent asthma." | 5.11 | Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma. ( Hsu, PC; Hua, YM; Hung, CH; Lai, YS; Li, CY; Yang, KD, 2005) |
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 5.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "In view of the possible systemic side-effects of inhaled corticosteroids (ICS), a study was performed to determine whether ketotifen (versus placebo) can replace or allow a reduction in the dose of ICS required for the maintenance treatment of childhood asthma." | 5.08 | Does ketotifen have a steroid-sparing effect in childhood asthma? ( Canny, GJ; Levison, H; Reisman, J, 1997) |
| "Administration of theophylline to asthmatic children is frequently associated with an adverse influence on their behavior." | 5.07 | Administration of half-dose theophylline together with ketotifen to asthmatic children--a double-blind, placebo-controlled study. ( Amir, J; Lerman, M; Malik, H; Varsano, I; Volovitz, B, 1994) |
| "Effects of ultrasonically nebulized distilled water (UNDW) on PtcO2 and PtcCO2 time courses were studied in 26 mild asthmatics (FEV1 non-responders) in basal conditions and monitored after 2, 6, 12 and 18 weeks of randomly allocated treatment with ketotifen 1 mg b." | 5.07 | Transcutaneous O2 and CO2 monitoring of bronchial responsiveness in FEV1 non-responder asthmatics during ketotifen and placebo treatment. ( Allegra, L; Dal Negro, R; Pomari, C; Turco, P, 1993) |
| "In an open clinical study, 80 children and adolescents of 12 months to 20 years of age suffering from asthma bronchiale were treated for a minimum of 8 weeks with DNCG (acecromol) or ketotifen (Zatofug) or with both drugs." | 5.07 | [DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma]. ( Kehnscherper, M, 1993) |
| "Ninety-six patients with nocturnal asthma (FEV1 = 60-90% pred, reversibility greater than or equal to 15%, at least 2 awakenings in the week preceding the trial) were included in a double-blind, randomized, crossover, multicenter study which compared the efficacy and side effects of inhaled salmeterol (50 micrograms morning and evening) to the association theophylline-ketotifen (300 mg and 1 mg morning and evening, respectively)." | 5.07 | [Usefulness of salmeterol in nocturnal asthma: a comparative study with theophylline-ketotifen association. A French multicenter group]. ( Georges, D; Muir, JF, 1992) |
| "To evaluate the prophylactic effect of ketotifen against the onset of asthma we selected 121 infants with atopic dermatitis, without any history suggestive of asthma (cough and/or wheezing)." | 5.07 | Prevention of asthma by ketotifen in infants with atopic dermatitis. ( Baba, M; Iikura, Y; Mikawa, H; Naspitz, CK; Nishima, S; Sole, D; Talaricoficho, S, 1992) |
| "Allergen-induced increase in airway responsiveness to histamine or methacholine provides a useful model for investigation of prophylactic or "antiinflammatory" asthma treatments." | 5.07 | Allergen-induced increase in airway responsiveness is not inhibited by acute treatment with ketotifen or clemastine. ( Cockcroft, DW; Gore, BC; Keshmiri, M; Murdock, KY, 1992) |
| "Ketotifen, an antianaphylactic and antihistamine drug was given orally to 31 asthma patients who had significant airflow limitation (mean FEV1% FVC = 65." | 5.06 | Pulmonary function parameters in asthma patients receiving oral ketotifen. ( Maselle, AY; Mashalla, YJ, 1990) |
| "Ketotifen was administered orally, for 3 months, to 40 children aged 3-14 years with chronic extrinsic asthma of moderate severity in a double-blind placebo-controlled study." | 5.06 | Effect of ketotifen on childhood asthma: a double-blind study. ( Anagnostakis, I; Hadziargurou, D; Liapi-Adamidou, G; Mylona-Karayanni, C; Saxoni-Papageorgiou, F; Sinaniotis, C, 1990) |
| "In order to determine whether treatment with ketotifen inhibits asthmatic reactions induced by toluene di-isocyanate (TDI), we studied six sensitized subjects with previously demonstrated dual or late asthmatic reaction after inhalation challenge with TDI." | 5.06 | Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects. ( Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L, 1989) |
| "The efficacy and tolerability of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin dihydrochloride) (2 mg twice daily orally) in comparison with ketotifen (1 mg twice daily orally) was investigated in 400 patients with bronchial asthma (picumast dihydrochloride n = 202, ketotifen n = 198) in a double-blind, controlled, parallel group study." | 5.06 | A one-year double-blind clinical study of the efficacy and tolerability of picumast dihydrochloride versus ketotifen in patients with bronchial asthma. ( Boerner, D; Müller, S; Slapke, J, 1989) |
| "Sixty children aged 5-13 years with moderately severe asthma took part in a double-blind, placebo-controlled trial of ketotifen." | 5.06 | Ketotifen in asthma. ( Dawson, KP; Fergusson, DM; Horwood, LJ; Mogridge, N, 1989) |
| "In a parallel, double-blind, placebo-controlled study we investigated the effect of the antiallergic drug Ketotifen on bronchial resistance (determined body plethysmographically) and beta 2-adrenoceptor density of lymphocytes (determined by 125-iodo-cyano-pindolol binding) in asthmatic children suffering from exercise-induced asthma (EIA)." | 5.06 | Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma. ( Braun, D; Griese, M; Kusenbach, G; Ludwig, J; Reinhardt, D, 1988) |
| "In order to examine a possible mechanism of action of ketotifen in asthma, a double-blind study was undertaken to determine whether ketotifen showed any effects on the beta-adrenergic system in asthmatic patients." | 5.06 | The effects of ketotifen on beta-adrenergic activity in asthmatics. ( Burge, PS; Gove, RI; Skinner, C; Stableforth, DE, 1988) |
| "In 2 clinical studies we tested the efficacy of ketotifen in allergic rhinitis and allergic bronchial asthma." | 5.06 | [Experience with ketotifen in respiratory tract diseases]. ( Jäger, L; Mohorn, M; Wenz, W, 1986) |
| "In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily." | 5.06 | Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults. ( Lim, TK; Tan, WC, 1987) |
| "Twelve subjects with stable asthma each inhaled two puffs (200 micrograms) of salbutamol on 2 separate days 3 h after double-blind oral administration of ketotifen (two 1-mg capsules) or identical placebo." | 5.06 | Effect of ketotifen on the bronchodilation induced by salbutamol. ( Baldanza, C; Bonanno, CT; Carpentiere, G; Castello, F; Marino, S, 1988) |
| "Thirty children (aged 1 to 3 years) with mild to moderate asthma were entered into a 28-week double-blind, crossover study comparing the prophylactic effect of ketotifen and placebo." | 5.06 | Efficacy and safety of ketotifen in young children with asthma. ( Cumella, JC; Jaber, L; Varsano, I; Volovitz, B, 1988) |
| "Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH)." | 5.06 | Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation? ( Biggs, BA; Ferguson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1987) |
| "The place of KETOTIFEN in the immunotherapy for atopic asthmatic patients (confirmed by cutaneous test and RAST) has been determined by a study conducted on 48 patients divided into two randomly selected parallel groups." | 5.06 | [Role of ketotifen in the immunotherapy of atopic asthmatics]. ( Haddad, G; Pacaud, D; Papeix, P; Steeg, LF; Tran, Q; Vincent, J, 1986) |
| "This double-blind parallel group study evaluated ketotifen 1 mg bid versus placebo in the treatment of 30 adult seasonally allergic asthmatics during the course of the spring pollen season." | 5.06 | The use of ketotifen in the prophylaxis of seasonal allergic asthma. ( Carroll, MS; Lotner, GZ; Spangler, DL; Tinkelman, DG; Vanderpool, GE; Webb, CS, 1986) |
| "5 years were studied with respect to the protective effect of ketotifen on pollen-induced bronchial asthma." | 5.06 | Ketotifen in pollen-induced asthma: a double blind placebo-controlled study. ( Broberger, U; Graff-Lonnevig, V; Lilja, G; Rylander, E, 1986) |
| "Forty-seven children with chronic asthma, aged 2 to 6 years, completed a double-blind, placebo-controlled, crossover trial of ketotifen, 1 mg twice daily, in the prophylaxis of asthma." | 5.06 | Long-term, placebo-controlled trial of ketotifen in the management of preschool children with asthma. ( Loftus, BG; Price, JF, 1987) |
| "The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study." | 5.05 | Ketotifen in adult asthma. ( Dyson, AJ; Mackay, AD, 1980) |
| "The results of clinical trials in patients with allergic bronchial asthma performed to demonstrate the therapeutic effect of the newly developed substance Ketotifen are reviewed: 1." | 5.05 | [Long-term therapy of bronchial asthma with ketotifen. European experiences]. ( Magnussen, H, 1980) |
| "A randomized multicentre trial was done to investigate the protective effects of ketotifen and disodium cromoglycate (DSCG) in the therapy of bronchial asthma." | 5.05 | [Treatment of seasonal asthmatic symptoms. A multicentre trial to compare the effects of ketotifen and disodium cromoglycate (author's transl)]. ( Borelli, S; Düngemann, H; Schiess, W, 1980) |
| "1 Ketotifen (HC 20-511 Sandoz) 1 mg twice daily for 12 weeks was found to be equivalent to sodium cromoglycate (SCG) 20 mg four times daily for 12 weeks in 35 skin test positive asthmatic patients in a randomised double-blind cross-over study." | 5.05 | A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma. ( Clarke, CW; May, CS, 1980) |
| "In a controlled single-blind study of 12 weeks' duration the prophylactic anti-asthmatic effects of ketotifen and clemastine in children with bronchial asthma were compared." | 5.05 | A comparison between the efficacy of ketotifen and clemastine in children. ( Gutová, M; Hlousek, Z; Hlousková, Z, 1980) |
| "The efficacy of ketotifen, a tricyclic benzocycloheptathiophene derivative, was assessed in an outpatient clinical trial and in a group of 12 asthmatic subjects with exercise-induced asthma." | 5.05 | Ketotifen in atopic asthma and exercise-induced asthma. ( Bierman, CW; McAllen, M; Moxham, J; Petheram, IS; Spiro, SG, 1981) |
| "Ketotifen, an orally active, prophylactic anti-asthmatic drug, was compared with placebo in a double-blind, three-month parallel-group trial in 20 children." | 5.05 | Ketotifen: a new drug for prophylaxis of asthma in children. ( Becker, AB; Gillespie, CA; Luciuk, GH; Simons, FE, 1982) |
| "A double blind crossover comparison of slow-release theophylline, ketotifen and placebo was carried out in 18 young children with perennial asthma." | 5.05 | A controlled comparison of slow-release theophylline, ketotifen and placebo in the prophylaxis of asthma in young children. ( Carswell, F; Fysh, WJ; Hughes, AO; Robinson, P; Stratton, D, 1983) |
| "Report on a double-blind parallel group comparison of ketotifen and placebo in two groups of twenty-five children with extrinsic bronchial asthma." | 5.05 | The prophylactic treatment of bronchial asthma in children with ketotifen: a double-blind comparison with placebo. ( Spicak, V, 1983) |
| "Clinical trials of slow-release theophylline and ketotifen as prophylaxis against asthma in 18 young children suggested that both drugs had some efficacy." | 5.05 | Double-blind comparisons of slow-release theophylline, ketotifen and placebo for prophylaxis of asthma in young children. ( Carswell, F; Fysh, WJ; Hughes, AO; Robinson, P; Stratton, D, 1984) |
| "2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG)." | 5.05 | Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys. ( Bevegård, S; Graff-Lonnevig, V; Lilja, G, 1983) |
| "The therapeutic effects of inhaled disodium cromoglycate (DSCG) and orally administered ketotifen were compared in thirty atopic asthmatics aged 15-34 years during a 22-week double-blind parallel group study." | 5.05 | A double-blind comparison of ketotifen and disodium cromoglycate in atopic adult asthmatics. ( Sears, MR, 1983) |
| "In a double-blind study we compared the effect of 2 mg ketotifen (Zaditen) daily and 1050 mg aminophylline daily for 6 months in two groups of altogether 24 patients with bronchial asthma and a chronic obstruction of the airways." | 5.05 | The influence of ketotifen and aminophylline on the central and peripheral airways. ( Dorow, P; Schiess, W, 1983) |
| "Thirty-six children with verified deciduous tree pollen-induced asthma were studied with respect to the prophylactic effect and tolerance of ketotifen, in comparison to disodium cromoglycate." | 5.05 | A comparative study of the prophylactic effect of ketotifen and sodium cromoglycate in children with pollen-induced asthma. ( Graff-Lonnevig, V; Kusoffsky, E, 1980) |
| "The protective effect of ketotifen was examined by an open assessment trial in 261 asthmatics of variable types, a double blind trial comparing ketotifen and inert placebo in 189 asthmatics of extrinsic type including pure atopic asthma and asthma with atopic and infectious components (mixed type or combined type), and a double blind trial comparing ketotifen and disodium cromoglycate (DSCG) by double placebo technique in 132 asthmatics of a pure atopic type." | 5.05 | Clinical evaluation of a new orally active anti-anaphylactic compound: ketotifen (HC 20-511) in Japanese adult asthmatics. ( Kumagai, A; Muranaka, M; Shida, T; Takahashi, T; Tomioka, H, 1980) |
| "The protective effect of ketotifen and disodium cromoglycate (DSCG) was evaluated by a randomised double blind cross-over study in 15 children with allergic bronchial asthma." | 5.05 | [Protective effect of ketotifen and disodium cromoglycate in bronchial challenge tests with allergens (author's transl)]. ( Hamm, M; Klein, G; Matthys, H; Urbanek, R, 1980) |
| "Sixty-four patients with mild of moderate extrinsic asthma were treated with placebo for 1 month and thereafter with ketotifen (1 mg twice daily, orally), disodium cromoglycate (inhalation of 20 mg, four times daily), or placebo for 2 subsequent months." | 5.05 | Comparison of ketotifen, disodium cromoglycate and placebo in the treatment of adult patients with mild extrinsic asthma. ( Ahonen, A; Haahtela, T; Hurme, R; Maasilta, P; Mattson, K; Muittari, A; Poppius, H; Venho, K, 1981) |
| "A double-blind non crossover trial comparing disodium cromoglycate (DSCG), with ketotifen, was carried out in twenty-seven extrinsic asthmatic children over 12 weeks." | 5.05 | A double-blind trial comparing disodium cromoglycate (DSCG), and ketotifen in extrinsic asthmatic children. ( Holgado de Cuesta, D; Schuhl, JF, 1981) |
| "Plasma histamine and serum neutrophil chemotactic activity (S-NCA) were measured in ten atopic asthmatic patients on four separate occasions after allergen bronchial provocation testing (BPT)." | 5.05 | Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds. ( Cundell, DR; Davies, RJ; Moodley, I; Morgan, DJ; Sheinman, BD; Smart, W, 1985) |
| "This study was designed to assess the acute effect of 1 mg of orally administered ketotifen on the dose-response curve to both histamine and methacholine, in 15 patients with bronchial asthma." | 5.05 | Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma. ( Barja, S; Cruz, E; Ferretti, R; Lisboa, C; Moran, J; Moreno, R; Sanchez, I, 1985) |
| "Three hundred seventy-four patients with asthma were entered into a year-long, double-blind, double-placebo controlled study comparing the prophylactic effect of ketotifen (229 patients), theophylline (73 patients), and placebo (72 patients)." | 5.05 | A multicenter trial of the prophylactic effect of ketotifen, theophylline, and placebo in atopic asthma. ( Buckley, CE; Bukantz, SC; Chodosh, S; Cohen, BM; Dobken, JH; Moss, BA; Rappaport, I; Rosenthal, RR; Sheffer, AL; Tinkelman, DG, 1985) |
| "In order to compare long-term changes induced on a wide spectrum of bronchial hyperreactivity (BH) by the antiallergic drugs disodium cromoglycate (DSCG) and ketotifen, 56 asthmatic patients (age range 15-55 years) were studied." | 5.05 | Long-term modification on histamine-induced bronchoconstriction by disodium cromoglycate and ketotifen versus placebo. ( Colas Sanz, C; de Barrio Fernandez, M; Gozalo Reques, F; Herrero Lopez, T; Rubio Sotes, M; Senent Sanchez, C, 1985) |
| "Seven hundred and thirty-three atopic asthmatic patients were entered into two multicenter double-blind double-placebo controlled studies comparing the prophylactic effects of ketotifen (445 patients), placebo (143 patients), disodium cromoglycate (72 patients) and theophylline (73 patients)." | 5.05 | A multicenter study with ketotifen (Zaditen). ( Burns, RB, 1985) |
| "12 patients with bronchial asthma received treatment with Ketotifen for three months." | 5.04 | [Ketotifen, a new prophylactic agent in asthma (author's transl)]. ( Fryda-Kaurimsky, Z; Giesen, HK, 1979) |
| "Ketotifen is an antihistamine which may be used to treat asthma." | 4.82 | Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. ( Bassler, D; Ducharme, FM; Forster, J; Mitra, A; Schwarzer, G, 2004) |
| "Since tranilast, the first inhibitor of chemical mediator (ICMR), had been assessed to be as effective as disodium cromogycate in asthma, several orally active ICMRs, which have no antihistamine or bronchodilator effect, have been developed and prescribed for asthma control in Japan." | 4.79 | [Inhibitor of chemical mediator release]. ( Fujimura, M, 1996) |
| "Ketotifen is an orally active prophylactic agent for the management of bronchial asthma and allergic disorders." | 4.78 | Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. ( Fitton, A; Goa, KL; Grant, SM; Sorkin, EM, 1990) |
| "The experimental data providing the rationale for the use of ketotifen as a prophylactic drug in asthma (inhibition of release of the mediators of anaphylaxis, particularly SRS-A, prevention of the bronchospasm induced by SRS-A in vivo, calcium antagonist effect) are briefly discussed, and the results of experimental and therapeutic trials carried out over 6 years in a number of countries in several thousand patients are reviewed." | 4.76 | Ketotifen in the oral prophylaxis of bronchial asthma: a review. ( Craps, L, 1981) |
| " Histamine and acetylcholine were used to guinea pigs to establish bronchospasm model." | 3.77 | Phytopharmacological evaluation and anti-asthmatic activity of Ficus religiosa leaves. ( Acharya, N; Acharya, S; Jasani, N; Kapoor, M; Kumar, V, 2011) |
| " Several well controlled studies have however shown that chronic administration of sympathomimetics results in a significantly decreased sensitivity of the bronchial beta adrenergic receptor." | 3.76 | [Bronchial adrenergic receptors and asthma. Tachyphylaxis and its prevention]. ( Pauwels, R, 1988) |
| "Montelukast and ketotifen are commonly prescribed anti-inflammatory medications used in the treatment of childhood asthma." | 3.74 | Suppression of plasma matrix metalloproteinase-9 following montelukast treatment in childhood asthma. ( Chuang, SS; Hsu, SH; Hua, YM; Hung, CH; Jong, YJ; Lin, CS; Tien, CH; Yang, KD, 2007) |
| "To explore the changes of leukotrienes (LT) in cerebral cortex and lung tissues in ovalbumin-induced rat asthma model and effects of different anti-asthma drugs on the changes." | 3.72 | Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats. ( Bian, RL; Chen, JQ; Deng, YM; Xie, QM, 2003) |
| "Using population-based, health care administrative data, children with possible asthma were identified as having one or more physician visits or hospitalizations for asthma or bronchitis diagnoses from January 1995 to December 1995, or, in the absence of asthma-like diagnoses, one or more prescriptions for asthma prophylaxis drugs or ketotifen concomitant with a beta-agonist, or two or more prescriptions for beta-agonists." | 3.72 | Identifying children with persistent asthma from health care administrative records. ( Becker, AB; Kozyrskyj, AL; Mustard, CA, 2004) |
| "The effects of betotastine besilate (betotastine: TAU-284), a novel antiallergic drug, on homologous passive cutaneous anaphylaxis (PCA), mediator-induced cutaneous reaction, antigen-induced asthmatic responses and platelet-activating factor (PAF)-induced airway eosinophilia in several animal models, were compared to ketotifen." | 3.70 | Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen. ( Inagaki, N; Koda, A; Nagai, H; Ueno, M, 1998) |
| "Chronic administration of theophylline can be used for treating asthma; it may represent a severe risk when some other drugs are prescribed by unaware physicians." | 3.69 | [Status epilepticus in an asthmatic child]. ( Bernard, JL; Bernard, O; Casha, P; Durand, A; Galland, MC; Koné-Paut, I; Pisano, P; Vialet, R, 1994) |
| " When leukocytes from asthmatic patients sensitive to mite were stimulated with the allergen, epinastine inhibited histamine release with a concentration required for 50% inhibition (IC50) of 3 x 10(-5) mol/l and leukotriene C4 generation." | 3.69 | Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes. ( Mita, H; Shida, T, 1995) |
| "The effect of antiallergic agents (DSCG) (disodium cromoglycate, ketotifen, and ibudilast) and beclomethasone dipropionate inhaler (BDI) on bronchial hyperresponsiveness to histamine inhalation was retrospectively assessed in 72 asthmatic patients with more than a year's duration of the disease." | 3.68 | Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study. ( Hoshino, K; Kawasaki, A; Kobayashi, M; Mizushima, Y; Oosaki, R; Yano, S, 1993) |
| "Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response." | 3.68 | Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992) |
| "The aim of the study was to evaluate the effect of ketotifen, nedocromil sodium and budesonide on non-specific bronchial hyperreactivity in asthmatic patients." | 3.68 | [Effect of ketotifen, nedocromil sodium and budesonide on non-specific bronchial hyperreactivity to histamine in patients with asthma]. ( Kazberuk, M; Rogalewska, A; Rutkowski, R; Siergiejko, Z, 1992) |
| "A study was made of the effect of ketotifen on the concentration of leukotriene B4, prostacyclin and thromboxane A2 in the liquid of bronchoalveolar lavage and on external respiration and cellular immunity during 4 weeks of the treatment of patients with infection-dependent bronchial asthma and chronic obstructive bronchitis." | 3.68 | [Effect of ketotifen on the eicosanoid system, immunoreactivity and bronchial patency in patients with obstructive pulmonary diseases]. ( Blazhko, VI; Bondar', TN; Efimov, VV; Liashenko, MM; Voeĭkova, LS, 1991) |
| "We tested the effect of Ketotifen (4-(1-methyl-4-piperidylidene)-4H- benzo[4,5] cyclohepta[1,2-b]thiophen-10(9H)-one hydrogen (fumarate) on the induction of allergen-induced IL-2 responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma." | 3.68 | Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma. ( Akasaka, T; Baba, M; Maeda, K; Noma, T; Yata, J; Yoshizawa, I, 1990) |
| "Effects of KB-2413 on experimental asthma and respiration were examined in comparison with ketotifen and chlorpheniramine in guinea pigs." | 3.67 | Antiasthmatic effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidaz ole difumarate (KB-2413), a new antiallergic. ( Fukuda, T; Ito, K; Saito, T, 1984) |
| "The mechanism of action of ketotifen in the prevention of bronchial asthma is discussed, the pathogenesis of the disease itself being taken as a starting point." | 3.67 | Ketotifen: current views on its mechanism of action and their therapeutic implications. ( Craps, LP; Ney, UM, 1984) |
| "In a postmarketing surveillance of ketotifen (Zaditen), an oral preparation for the prophylaxis of bronchial asthma, 8291 patients completed records every three months for one year." | 3.67 | Postmarketing surveillance: practical experience with ketotifen. ( Crowder, D; Maclay, WP; Spiro, S; Turner, P, 1984) |
| "The inhibition of immediate allergen or histamine induced airflow obstruction by inhaled ketotifen, clemastine, sodium cromoglycate, and placebo was studied in two groups of asthmatic subjects." | 3.67 | Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma. ( Davies, RJ; Gould, C; Ollier, S; Phillips, MJ, 1984) |
| "Ten patients with allergic asthma were studied to compare the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses, especially the late asthmatic response, induced by house dust allergen in bronchial provocation tests." | 3.67 | A comparison of the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses to house dust, with special reference to the late asthmatic response. ( Adachi, M; Aoki, N; Furuya, A; Iijima, M; Kobayashi, H; Kokubu, F; Takahashi, T, 1984) |
| " Certain drugs such as antihistamines and ketotifen may be more effective administered by inhalation since high concentrations with reduced unwanted effects can be achieved on the bronchial surface where, in allergic asthma, the critical initial interaction between sensitized mast cells (mucosal?) and allergen with subsequent mediator release occurs." | 3.67 | Use of inhaled calcium channel blocking agents in the treatment of asthma. ( Bennett, J; Davies, RJ; Osman, J, 1984) |
| "Twelve children with pollinosis or bronchial asthma were treated continuously, without interruption, for 6 months with ketotifen (2 mg per day)." | 3.67 | Growth hormone plasma levels in children treated for 6 months with ketotifen. ( Dolecek, R; Halatová, A; Janstová, V, 1984) |
| "Parallel clinico-pharmacological studies were carried out of ketotifen action in patients with atopic bronchial asthma and in an experimental model of beta-adrenergic blockade in guinea pigs." | 3.67 | [The possible effect of a ketotifen preparation on beta-receptor blockade]. ( Kosturkov, G; Markov, M; Popov, T; Vŭlcheva, T, 1989) |
| "An open pilot study was carried out over a period of more than 2 years to assess the steroid-sparing effect of ketotifen (1 mg twice daily) in 12 steroid-dependent asthmatic patients." | 3.67 | Steroid-sparing effect of ketotifen in steroid-dependent asthmatics: a long period evaluation in 12 patients. ( Izumi, S; Kasuya, S, 1988) |
| "In 13 patients with bronchial asthma, who were on beta 2-adrenergic bronchodilator therapy, the effects of prednisolone and ketotifen on lymphocyte beta 2-adrenoceptor density and -responsiveness were investigated." | 3.67 | Effect of prednisolone and ketotifen on beta 2-adrenoceptors in asthmatic patients receiving beta 2-bronchodilators. ( Brodde, OE; Egerszegi, S; Howe, U; Konietzko, N; Michel, MC, 1988) |
| "This study was undertaken to investigate the effect of ketotifen on the immune system of asthmatic children receiving prophylactic treatment with ketotifen." | 3.67 | Cellular immunity and suppressor T cell function in asthmatic children on prolonged ketotifen therapy. ( Armoni, M; Bibi, H; Fink, A; Schlesinger, M; Schwartz, Y; Shapira, H; Tabachnik, E, 1988) |
| "The prophylaxis of childhood asthma is discussed under the headings of prevention by the pregnant mother in avoiding hypersensitizing foods and the adherence to breast feeding, immunotherapy of the child and chemoprophylaxis by sodium cromoglycate or ketotifen fumarate." | 3.67 | Prophylactic treatment of childhood asthma. ( Castello, D, 1986) |
| "The results obtained with Ketotifen in 36 asthmatic children followed up during 12 months in the paediatrics department of the University Clinic of Kinshasa are reported." | 3.67 | [Clinical results of the treatment with ketotifen in asthmatic children in Zaire. Apropos of 36 cases followed at university clinics in Kinshasa (Zaire)]. ( Disengomoka-Muamba, I; Kanku, T, 1987) |
| "Alterations of the entire immunity profile of bronchial asthma patients have been studied following a half-year long Ketotifen treatment." | 3.67 | Ketotifen action upon the immunity state in bronchial asthma. ( Zavázal, V, 1985) |
| "Ketotifen, a benzocycloheptathiophene, possesses asthma-prophylactic and antiallergic activities in a number of in vitro and in vivo systems: prevention of cutaneous and lung anaphylaxis in the rat and guinea pig; inhibition of dermal and bronchial antigen challenges in man; inhibition of mediator release from rat mast cells, human basophils, human neutrophils, and human and guinea pig chopped lung; reduction of human neutrophil activation induced by PAF-acether; functional antagonism of mediator effects in the guinea pig; blockade of H1-receptors and prevention and reversal of beta-adrenergic tachyphylaxis in the rat." | 3.67 | Immunologic and therapeutic aspects of ketotifen. ( Craps, LP, 1985) |
| "Ketotifen administered prior to aspirin offered protection against bronchoconstriction in 13 of 14 patients with aspirin-sensitive asthma." | 3.66 | Inhibition by ketotifen of idiosyncratic reactions to aspirin. ( Czerniawska-Mysik, G; Kuklinski, P; Serwonska, M; Szczeklik, A, 1980) |
| " Recommended initial outpatient treatment of sporadic asthma consists of administration of an inhaled beta 2 agent, followed as necessary by a systemic beta 2 agent, a long-acting theophylline preparation, cromolyn, and inhaled ipratropium." | 3.66 | Asthma therapy. Advantages and limitations of various approaches. ( Schwartz, SH, 1983) |
| " The published studies concerning the use of ketotifen in asthma are reviewed." | 3.66 | Prophylactic drugs in asthma. ( Anderson, G, 1983) |
| "Sixty-four patients with confirmed bronchial asthma were treated with HC 20-511 (Ketotifen)." | 3.66 | Clinical effects of HC 20-511 (ketotifen) in bronchial asthma and its inhibitory effect on antigen-induced morphological changes of basophils. ( Goda, Y; Harada, H; Kimura, I; Sasaki, Y; Takahashi, K; Tanizaki, Y, 1980) |
| "By repeated inhalant carbachol provocation tests on 13 normal and 13 asthmatic subjects, we investigated the effect of ketotifen (as compared with placebo) on the cholinergic responsiveness of the airways." | 3.66 | Effects of ketotifen on cholinergic induced airway obstruction. ( Klein, G; Köhler, D; Matthys, H; Schiess, W; Schulz, N, 1983) |
| "Some important pharmacodynamic and clinical data on ketotifen, a benzocycloheptathiophene used in the prophylaxis of allergic asthma, are provided as an introduction to papers discussing the therapeutic use of this substance in adults and children." | 3.66 | [Ketotifene: experimental and clinical data]. ( Craps, L, 1980) |
| "In a multicentre, double-blind trial, the steroid sparing effect of a new anti-anaphylactic agent ketotifen was assessed against placebo in eighty-six steroid-dependent asthmatics." | 3.66 | A steroid sparing effect of ketotifen in steroid-dependent asthmatics. ( Lane, DJ, 1980) |
| "The pharmacodynamic effects of ketotifen, a benzocycloheptathiophene derivative, on several partly interdependent biological pathways (calcium fluxes in excitable cells, production and release of mediators, mainly SRS-A, smooth-muscle contractility, density and sensitivity of adrenergic receptors) may be relevant to its antianaphylactic and asthma-prophylactic properties." | 3.66 | Ketotifen in the prophylaxis of bronchial asthma. ( Craps, L, 1982) |
| "23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules." | 3.66 | [Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980) |
| "Published pharmacokinetic data on ketotifen are sparse, although it is a commonly used prophylactic agent in various allergic disorders in adults and children." | 2.68 | Ketotifen pharmacokinetics in children with atopic perennial asthma. ( Ludden, TM; McFadyen, ML; Miller, R, 1997) |
| "The ketotifen dosage was 0." | 2.67 | Multicenter study with ketotifen (Zaditen) oral drop solution in the treatment of wheezy children aged 6 months to 3 years. ( Rotchild, M; Schlessinger, M; Soferman, R; Tabachnik, E; Tal, A; Varsano, I; Volovitz, B, 1993) |
| "A double-masked study was performed to investigate a possible side effect of the antiallergic substance Picumast dihydrochloride on lens transparency." | 2.67 | Lens safety study with Picumast dihydrochloride--a double masked study using the Scheimpflug method. ( Goder, G; Hockwin, O; Laser, H; Meinel, U; Messinger, D; Müller-Breitenkamp, U, 1990) |
| " Of the patients who were unable to stop taking theophylline, the Zaditen-and placebo-treated groups recorded average dosage reductions of 62% and 26%, respectively." | 2.66 | A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years. ( Brown, CA; Chandra, RK; Ho, P; Hoogerwerf, PE; Kennedy, RJ; Knight, A; Langer, H; Milne, J; Moote, DW; Rackham, A, 1989) |
| "In 12 patients with bronchial asthma we performed histamine bronchial challenges before and four hours after ingestion of placebo, 2." | 2.66 | The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients. ( Magnussen, H, 1987) |
| "Ketotifen was not associated with any adverse effects and did not cause behavioural problems." | 2.66 | Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma. ( el Beshlawy, A; el Hefny, A; Nour, S; Said, M, 1986) |
| "Eighteen children with perennial bronchial asthma with an average age of 9." | 2.66 | The effect of ketotifen on bronchial hyperreactivity in childhood asthma. ( Graff-Lonnevig, V; Hedlin, G, 1985) |
| " Compliance with therapy in adolescents in particularly low if the dosing regimen is more than twice daily, with poor inhaler technique contributing to ineffective control." | 2.40 | The problems of treating adolescent asthma: what are the alternatives to inhaled therapy? ( Kemp, J; Price, J, 1999) |
| "Opinions on the pathogenesis of bronchial asthma have changed considerably in recent years." | 2.38 | Prophylaxis in childhood asthma. ( Noche, ML, 1990) |
| " Percentage of dosage of beta 2 adrenergics inhaled as against the total of beta 2 (oral and inhaled)." | 1.29 | [Evaluation of the impact of a care program for asthmatic children on the quality of anti-asthma drug prescriptions]. ( Alba, F; Gimeno, J; González, M; Madridejos, R, 1995) |
| "It is clear that bronchial asthma is caused by chronic airway inflammation." | 1.29 | [The effect of ketotifen on the inflammation of bronchial mucosa in atopic asthmatics]. ( Hoshino, M, 1994) |
| "We treated bronchial asthma patients with anti-allergic agents for more than three months, and examined their effects on the airway hyperreactivity in 15 cases; five were short cases (disease duration was less than one year from the onset) and 10 were long cases (disease duration was more than one year)." | 1.28 | [Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents]. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Yano, S, 1989) |
| " There was a significant decrease in the density of beta-adrenoceptors following chronic administration of terbutaline." | 1.27 | Ketotifen prevents terbutaline-induced down-regulation of beta-adrenoceptors in guinea pig lung. ( Agrawal, DK; Koshino, T; Townley, RG; Townley, TA, 1988) |
| "Forty patients with atopic bronchial asthma were studied, aged from 16 to 54 (average age 34,4 years), with a duration of the disease from 1 to 22 years (average duration 10,8 years)." | 1.27 | [Comparative study of the effect of intal and zaditen in patients with atopic bronchial asthma at Sandanski health resort]. ( Petrov, D; Stoeva, N; Tsvetkov, O, 1985) |
| "A general scheme of long-term treatment of bronchial asthma and the author's own results of immunotherapy, prophylaxis and other experiences in controlling the disease are presented." | 1.26 | Contemporary problems of epidemiology and treatment of respiratory allergies and bronchial asthma. ( Zavázal, V, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 236 (71.73) | 18.7374 |
| 1990's | 72 (21.88) | 18.2507 |
| 2000's | 16 (4.86) | 29.6817 |
| 2010's | 4 (1.22) | 24.3611 |
| 2020's | 1 (0.30) | 2.80 |
| Authors | Studies |
|---|---|
| Paris, D | 1 |
| Cottin, M | 1 |
| Demonchaux, P | 1 |
| Augert, G | 1 |
| Dupassieux, P | 1 |
| Lenoir, P | 1 |
| Peck, MJ | 1 |
| Jasserand, D | 1 |
| Azari, F | 1 |
| Ghanbarzadeh, S | 1 |
| Safdari, R | 1 |
| Yaqoubi, S | 1 |
| Adibkia, K | 1 |
| Hamishehkar, H | 1 |
| Zhu, XH | 1 |
| Tu, JW | 1 |
| Dai, JH | 1 |
| Asawa, A | 1 |
| Simpson, KH | 1 |
| Bonds, RS | 1 |
| Yoshihara, S | 1 |
| Ono, M | 1 |
| Yamada, Y | 1 |
| Fukuda, H | 1 |
| Abe, T | 1 |
| Arisaka, O | 1 |
| Ngamphaiboon, J | 1 |
| Wirawarn, T | 1 |
| Thongkaew, T | 1 |
| Tantichaiyakul, P | 1 |
| Preutthipan, A | 1 |
| Kapoor, M | 1 |
| Jasani, N | 1 |
| Acharya, N | 1 |
| Acharya, S | 1 |
| Kumar, V | 1 |
| Chen, CY | 1 |
| Chiu, HF | 1 |
| Yeh, MK | 1 |
| Chang, CC | 1 |
| Yang, CY | 1 |
| Deng, YM | 2 |
| Xie, QM | 2 |
| Chen, JQ | 2 |
| Bian, RL | 2 |
| Schwarzer, G | 1 |
| Bassler, D | 1 |
| Mitra, A | 1 |
| Ducharme, FM | 1 |
| Forster, J | 1 |
| Kozyrskyj, AL | 1 |
| Mustard, CA | 1 |
| Becker, AB | 2 |
| Zhang, SJ | 1 |
| Yang, QH | 1 |
| Hung, CH | 3 |
| Li, CY | 2 |
| Lai, YS | 2 |
| Hsu, PC | 1 |
| Hua, YM | 3 |
| Yang, KD | 3 |
| Diamant, Z | 1 |
| Boot, JD | 1 |
| Virchow, JC | 1 |
| Jong, YJ | 2 |
| Chang, HC | 1 |
| Kaditis, AG | 1 |
| Winnie, G | 1 |
| Syrogiannopoulos, GA | 1 |
| Chuang, SS | 1 |
| Tien, CH | 1 |
| Hsu, SH | 1 |
| Lin, CS | 1 |
| Werner-Klein, M | 1 |
| Göggel, R | 1 |
| Westhof, A | 1 |
| Erb, KJ | 1 |
| Ferrari, M | 2 |
| Olivieri, M | 1 |
| Adami, S | 1 |
| Barozzi, E | 1 |
| Enrico Senna, G | 1 |
| Padovani, R | 1 |
| Droszcz, W | 2 |
| Dyson, AJ | 1 |
| Mackay, AD | 1 |
| Magnussen, H | 5 |
| Düngemann, H | 1 |
| Borelli, S | 1 |
| Schiess, W | 4 |
| Stangl, B | 1 |
| Furlan, J | 1 |
| Ustar, M | 1 |
| Janezic, A | 1 |
| Clarke, CW | 1 |
| May, CS | 1 |
| Hlousková, Z | 1 |
| Gutová, M | 1 |
| Hlousek, Z | 1 |
| Szczeklik, A | 3 |
| Czerniawska-Mysik, G | 4 |
| Serwonska, M | 2 |
| Kuklinski, P | 2 |
| Chachaj, W | 1 |
| Małolepszy, J | 1 |
| Liebhart, E | 1 |
| Liebhart, J | 1 |
| Kraus-Filarska, M | 1 |
| Panaszek, B | 1 |
| Komarov, FI | 1 |
| Daniliak, IG | 1 |
| Tsvetkova, OA | 1 |
| Gavrilov, VN | 1 |
| Klein, G | 4 |
| Urbanek, R | 4 |
| Matthys, H | 4 |
| Petheram, IS | 1 |
| Moxham, J | 1 |
| Bierman, CW | 1 |
| McAllen, M | 1 |
| Spiro, SG | 2 |
| Craps, L | 5 |
| Simons, FE | 1 |
| Luciuk, GH | 1 |
| Gillespie, CA | 1 |
| Herman, D | 1 |
| Vidart, JN | 1 |
| Flenley, DC | 2 |
| Burns, RB | 3 |
| Brandon, ML | 1 |
| Haddad, ZH | 1 |
| Falliers, CJ | 2 |
| Lakshminarayan, S | 1 |
| Podleski, WK | 3 |
| Townley, RG | 2 |
| Schwartz, SH | 1 |
| Balabolkin, II | 2 |
| Matus, NI | 1 |
| Girón Caro, F | 1 |
| Svedmyr, N | 1 |
| Green, ID | 1 |
| Furukawa, CT | 1 |
| Fukuda, T | 1 |
| Saito, T | 1 |
| Ito, K | 1 |
| Seropian, E | 1 |
| Filip, V | 1 |
| Iamandescu, I | 1 |
| Craps, LP | 3 |
| Ney, UM | 1 |
| Nolte, D | 1 |
| Dorward, AJ | 2 |
| Patel, KR | 2 |
| Debelic, M | 2 |
| Bretz, U | 1 |
| Martin, U | 1 |
| Mazzoni, L | 2 |
| Engel, G | 1 |
| Reinert, H | 1 |
| Sokolova, TS | 4 |
| Iurkov, IuA | 1 |
| Bakanov, MI | 1 |
| Reznik, IB | 1 |
| Zakhidov, IuV | 3 |
| Phanuphak, P | 1 |
| Carswell, F | 2 |
| Stratton, D | 2 |
| Hughes, AO | 2 |
| Fysh, WJ | 2 |
| Robinson, P | 2 |
| Mathov, E | 1 |
| Grinstein, M | 1 |
| Greiding, L | 1 |
| Salmun, N | 1 |
| Núñez, J | 1 |
| Cortegiani, D | 1 |
| Trento, H | 1 |
| Capolungo, O | 1 |
| Simkin, G | 1 |
| Spicak, V | 2 |
| Catterall, JR | 1 |
| Calverley, PM | 1 |
| Power, JT | 1 |
| Shapiro, CM | 1 |
| Douglas, NJ | 1 |
| Sciślicki, A | 1 |
| Rudnik, J | 1 |
| Gaweł, J | 1 |
| Lukasik, A | 1 |
| Werys, R | 1 |
| Matoga, S | 1 |
| Brański, H | 1 |
| Hsieh, KH | 1 |
| Fuangtong, R | 1 |
| Baskaranathan, S | 1 |
| Powar, JS | 1 |
| Bisseru, B | 1 |
| Palmen, FM | 1 |
| Lilja, G | 2 |
| Graff-Lonnevig, V | 6 |
| Bevegård, S | 1 |
| Delaney, JC | 1 |
| Sears, MR | 5 |
| Fischer, JF | 1 |
| Meister, W | 1 |
| Mohorn, M | 2 |
| Ellul-Micallef, R | 1 |
| Paterson, JW | 2 |
| Yellin, RH | 1 |
| Tarala, RA | 1 |
| Anderson, G | 2 |
| Barthel, E | 1 |
| Rozniecki, J | 2 |
| Górski, P | 1 |
| Szmidt, M | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Maclay, WP | 1 |
| Crowder, D | 1 |
| Spiro, S | 1 |
| Turner, P | 1 |
| Zelenak, TM | 1 |
| Schmidt, JL | 2 |
| Arif, MA | 1 |
| Nizami, SQ | 1 |
| Phillips, MJ | 1 |
| Ollier, S | 2 |
| Gould, C | 1 |
| Davies, RJ | 4 |
| Adachi, M | 1 |
| Kobayashi, H | 1 |
| Aoki, N | 1 |
| Iijima, M | 1 |
| Kokubu, F | 1 |
| Furuya, A | 1 |
| Takahashi, T | 2 |
| Bennett, J | 1 |
| Osman, J | 2 |
| Naspitz, CK | 2 |
| Tanizaki, Y | 1 |
| Takahashi, K | 2 |
| Goda, Y | 1 |
| Sasaki, Y | 1 |
| Harada, H | 1 |
| Kimura, I | 2 |
| Brook, U | 1 |
| Stancić, M | 1 |
| Dolecek, R | 2 |
| Halatová, A | 2 |
| Janstová, V | 2 |
| Panaszek, BA | 1 |
| Zychowicz, C | 1 |
| Siewierska, B | 1 |
| Nowacka, K | 1 |
| Kmiotek, W | 1 |
| Köhler, D | 1 |
| Schulz, N | 1 |
| Reviakina, VA | 2 |
| Partsalis, EM | 1 |
| Botvin'eva, VV | 2 |
| Lisboa, C | 3 |
| Moreno, R | 2 |
| Cruz, E | 3 |
| Barja, S | 2 |
| Moran, J | 2 |
| Sánchez, I | 2 |
| Ferretti, R | 3 |
| Zhukovskiĭ, AM | 1 |
| Mgone, CS | 1 |
| Dorow, P | 2 |
| Sainmont, C | 1 |
| Duprat, P | 1 |
| Bourdain, M | 1 |
| Loria, Y | 1 |
| Petrov, D | 2 |
| Stoeva, N | 2 |
| Eiser, NM | 1 |
| Dano, P | 1 |
| Aubry, P | 1 |
| Kusoffsky, E | 2 |
| Kumagai, A | 1 |
| Tomioka, H | 3 |
| Shida, T | 2 |
| Muranaka, M | 1 |
| Lech, B | 1 |
| Madalińska, M | 1 |
| Garlicki, A | 1 |
| Piotrowska, B | 1 |
| Chazan, R | 1 |
| von Wichert, P | 1 |
| Morris, MJ | 1 |
| Lane, DJ | 2 |
| Lamarre, A | 1 |
| Vincke, P | 1 |
| Lapierre, JG | 1 |
| Ackermans, F | 1 |
| Mattson, K | 2 |
| Poppius, H | 2 |
| Ahonen, A | 2 |
| Haahtela, T | 2 |
| Hurme, R | 2 |
| Maasilta, P | 2 |
| Muittari, A | 2 |
| Venho, K | 2 |
| Adamek-Guzik, T | 1 |
| Wołoszynski, J | 1 |
| Koterba, A | 1 |
| Kennedy, JD | 1 |
| Hasham, F | 1 |
| Clay, MJ | 1 |
| Jones, RS | 1 |
| Cameron, E | 1 |
| Hamm, M | 1 |
| Tanser, AR | 1 |
| Elmes, J | 1 |
| Zavázal, V | 2 |
| Sarsfield, JK | 1 |
| Stemmann, EA | 1 |
| Weihermann, D | 1 |
| Schachoff, R | 1 |
| Schuhl, JF | 1 |
| Holgado de Cuesta, D | 1 |
| Kennedy, GR | 2 |
| Sherriff, JM | 2 |
| Zellweger, JP | 1 |
| MacDonald, GF | 1 |
| Lowhagen, O | 1 |
| Warner, JO | 1 |
| Goldsworthy, SJ | 1 |
| Herjavecz, I | 2 |
| Böszörmény-Nagy, G | 1 |
| Monie, RD | 1 |
| Smith, AP | 1 |
| Leopold, D | 1 |
| Davies, BH | 1 |
| Thomas, GO | 1 |
| Schubotz, R | 1 |
| Groggins, RC | 1 |
| Hiller, EJ | 1 |
| Milner, AD | 1 |
| Stokes, GM | 1 |
| Grimm, R | 1 |
| Farina, JC | 1 |
| Krupp, P | 1 |
| Ullah, MI | 1 |
| Brostoff, J | 1 |
| Saunders, KB | 1 |
| Tuchinda, M | 1 |
| Habanananda, S | 1 |
| Mulhern, B | 1 |
| O'Connor, N | 1 |
| Hillery, M | 1 |
| Ward, OC | 1 |
| Sclano, G | 1 |
| Kadijević, Z | 1 |
| Girard, JP | 1 |
| Hartmann, A | 1 |
| Bühlmann, AA | 1 |
| Papp, I | 1 |
| Michalicka, D | 1 |
| Zajdlíková, E | 1 |
| Ferencíková, J | 1 |
| Ratajová, V | 1 |
| Harth, SC | 4 |
| Thong, YH | 4 |
| Hossain, M | 1 |
| Okubo, Y | 1 |
| Sekiguchi, M | 1 |
| Radielovic, P | 4 |
| Morley, J | 6 |
| Hansel, TT | 1 |
| Medici, TC | 3 |
| Croce, J | 1 |
| Negreiros, EB | 1 |
| Mazzei, JA | 1 |
| Isturiz, G | 1 |
| Alba, F | 1 |
| Madridejos, R | 1 |
| Gimeno, J | 1 |
| González, M | 1 |
| Bustos, GJ | 2 |
| Bustos, D | 1 |
| Romero, O | 1 |
| Tasaka, K | 1 |
| Saeed, SA | 1 |
| Ali, N | 1 |
| Saleem, S | 1 |
| Clough, J | 1 |
| Casha, P | 1 |
| Bernard, O | 1 |
| Galland, MC | 1 |
| Pisano, P | 1 |
| Koné-Paut, I | 1 |
| Vialet, R | 1 |
| Durand, A | 1 |
| Bernard, JL | 1 |
| Lulich, KM | 1 |
| Goldie, RG | 1 |
| Mita, H | 1 |
| Kurosawa, M | 1 |
| Hoshino, M | 3 |
| Volovitz, B | 4 |
| Amir, J | 1 |
| Malik, H | 1 |
| Lerman, M | 1 |
| Varsano, I | 4 |
| Donatini, B | 1 |
| Allegra, L | 1 |
| Turco, P | 2 |
| Pomari, C | 2 |
| Dal Negro, R | 1 |
| Kehnscherper, M | 1 |
| Soferman, R | 1 |
| Tal, A | 1 |
| Schlessinger, M | 1 |
| Rotchild, M | 1 |
| Tabachnik, E | 2 |
| Hoshino, K | 2 |
| Kawasaki, A | 2 |
| Mizushima, Y | 2 |
| Oosaki, R | 1 |
| Yano, S | 3 |
| Kobayashi, M | 1 |
| Fujimura, M | 1 |
| Canny, GJ | 1 |
| Reisman, J | 1 |
| Levison, H | 1 |
| Kumar, L | 1 |
| Tanaka, Y | 1 |
| Masai, E | 1 |
| Yashima, T | 1 |
| Furukawa, M | 1 |
| Kawano, Y | 1 |
| Yoshizawa, I | 2 |
| Baba, M | 5 |
| Noma, T | 2 |
| McFadyen, ML | 1 |
| Miller, R | 1 |
| Ludden, TM | 1 |
| Nakamura, Y | 2 |
| Shin, Z | 1 |
| Fukushima, Y | 1 |
| González Silva, M | 1 |
| Botero Flores, L | 1 |
| Ueno, M | 1 |
| Inagaki, N | 1 |
| Nagai, H | 2 |
| Koda, A | 2 |
| Zhang, XP | 1 |
| Wang, MX | 1 |
| Chen, SH | 1 |
| Sim, JJ | 1 |
| Donato, L | 1 |
| Kuhn, P | 1 |
| Cerveau, C | 1 |
| Charles, X | 1 |
| Chognot, D | 1 |
| Mancel, E | 1 |
| Drouet, M | 2 |
| Sabbah, A | 1 |
| Price, J | 1 |
| Kemp, J | 1 |
| Knol, K | 2 |
| Kabra, SK | 1 |
| Pandey, RM | 1 |
| Singh, R | 1 |
| Seth, V | 1 |
| Luiz, N | 1 |
| Nevzorova, VA | 1 |
| Prosekova, EV | 1 |
| Gel'tser, BI | 1 |
| Luk'ianov, PA | 1 |
| Shestovskaia, TN | 1 |
| Maĭstrovskaia, IuV | 1 |
| Arzamastseva, AI | 1 |
| Giesen, HK | 1 |
| Fryda-Kaurimsky, Z | 1 |
| Handley, DA | 1 |
| DeLeo, JJ | 1 |
| Havill, AM | 1 |
| Siergiejko, Z | 1 |
| Rutkowski, R | 1 |
| Rogalewska, A | 1 |
| Kazberuk, M | 1 |
| Muir, JF | 2 |
| Georges, D | 2 |
| Bertin, L | 1 |
| Iikura, Y | 2 |
| Mikawa, H | 2 |
| Talaricoficho, S | 1 |
| Sole, D | 1 |
| Nishima, S | 2 |
| Cockcroft, DW | 1 |
| Keshmiri, M | 1 |
| Murdock, KY | 1 |
| Gore, BC | 1 |
| Govil, YC | 1 |
| Misra, PK | 1 |
| Efimov, VV | 1 |
| Blazhko, VI | 1 |
| Liashenko, MM | 1 |
| Voeĭkova, LS | 1 |
| Bondar', TN | 1 |
| Leblond, H | 1 |
| Castillo, JG | 1 |
| Oehling, A | 1 |
| Gamboa, PM | 1 |
| Louis, R | 1 |
| Radermecker, M | 1 |
| Misawa, M | 1 |
| Kanai, Y | 1 |
| Chiba, Y | 1 |
| Kishimoto, T | 1 |
| Sato, T | 1 |
| Ono, T | 1 |
| Nakagawa, T | 1 |
| Nakashima, A | 1 |
| Knight, A | 2 |
| Nickerson, GH | 1 |
| Moote, DW | 2 |
| St-Pierre, JP | 1 |
| Huszar, E | 1 |
| Böszörmenyi-Nagy, G | 1 |
| Slapke, J | 2 |
| Schreiber, J | 1 |
| Debreczeni, LA | 1 |
| Makino, E | 1 |
| Ohashi, T | 1 |
| Takahashi, H | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Azuma, H | 1 |
| Hockwin, O | 1 |
| Müller-Breitenkamp, U | 1 |
| Laser, H | 1 |
| Messinger, D | 1 |
| Goder, G | 1 |
| Meinel, U | 1 |
| Maeda, K | 2 |
| Akasaka, T | 2 |
| Masaki, T | 1 |
| Arita, M | 1 |
| Niiya, H | 1 |
| Koya, N | 3 |
| Mashalla, YJ | 1 |
| Maselle, AY | 1 |
| Noche, ML | 1 |
| Hane, AA | 1 |
| Kane/Fall, AM | 1 |
| Ndir, M | 1 |
| Ayad, M | 1 |
| Badiane, M | 1 |
| Kane, PA | 1 |
| Kerrebijn, KF | 1 |
| Ukena, D | 1 |
| Schlimmer, P | 1 |
| Vogt, J | 1 |
| Sybrecht, GW | 1 |
| Mylona-Karayanni, C | 1 |
| Hadziargurou, D | 1 |
| Liapi-Adamidou, G | 1 |
| Anagnostakis, I | 1 |
| Sinaniotis, C | 1 |
| Saxoni-Papageorgiou, F | 1 |
| Grant, SM | 1 |
| Goa, KL | 1 |
| Fitton, A | 1 |
| Sorkin, EM | 1 |
| Yata, J | 1 |
| Mizutani, M | 1 |
| Tateno, A | 2 |
| Suzuki, S | 2 |
| Sasamoto, A | 1 |
| Abe, Y | 1 |
| Saito, S | 1 |
| Moroi, T | 2 |
| Tomioka, S | 1 |
| Kuroiwa, H | 1 |
| Hara, M | 1 |
| Nagata, K | 1 |
| Pelikan, Z | 1 |
| Pelikan-Filipek, M | 1 |
| Chihara, J | 1 |
| Kubo, H | 1 |
| Sakurada, R | 1 |
| Yamamoto, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Inhaled Corticosteroids in Preschool Children Following Hospital Admission for Acute Dyspnea and Wheeze[NCT00962299] | Phase 4 | 7 participants (Actual) | Interventional | 2010-05-31 | Terminated (stopped due to recruitment was unsuccesfull, only 7 patient have been included untill 2012) | ||
| The Effect of Montelukast Therapy on mRNA Profile of Matrix Metalloproteinases and Their Inhibitors in the Sputum of Patients With Asthma[NCT00947453] | Phase 2 | 15 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| Double-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal Eosinophilia[NCT02484248] | Phase 3 | 40 participants (Anticipated) | Interventional | 2015-08-31 | Active, not recruiting | ||
| Ketotifen as a Treatment for Vascular Leakage During Dengue Fever (KETODEN)[NCT02673840] | Phase 4 | 110 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
38 reviews available for ketotifen and Asthma
| Article | Year |
|---|---|
Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children.
Topics: Anti-Asthmatic Agents; Asthma; Child; Histamine H1 Antagonists; Humans; Ketotifen; Randomized Contro | 2004 |
Summing up 100 years of asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Cholinergic Antago | 2007 |
Anti-inflammatory pharmacotherapy for wheezing in preschool children.
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cetirizine; Chi | 2007 |
Ketotifen in the oral prophylaxis of bronchial asthma: a review.
Topics: Asthma; Bronchi; Cromolyn Sodium; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Irrit | 1981 |
[Ketotifen in the prevention of bronchial asthma. International therapeutic evaluation].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Asthma; Bronchial Provocation Tests; Bronchodilator Age | 1981 |
New drugs in respiratory disorders: I.
Topics: Adrenergic beta-Agonists; Aerosols; Asthma; Betamethasone; Bronchodilator Agents; Cromolyn Sodium; D | 1983 |
[Effectiveness of the use of zaditen in allergic dermatoses and the dermorespiratory syndrome in children].
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Histamine H1 Antagoni | 1983 |
Therapeutic progress--review XI. Drugs in asthma.
Topics: Adrenergic beta-Agonists; Asthma; Calcium Channel Blockers; Cromolyn Sodium; Humans; Ipratropium; Ke | 1984 |
Prophylaxis of asthma with ketotifen in children and adolescents: a review.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Clemastine; Clinical Trial | 1983 |
[Current dosed aerosols in the treatment of obstructive respiratory tract diseases. 1. Intal].
Topics: Aerosols; Asthma; Bronchi; Chemical Phenomena; Chemistry; Cromolyn Sodium; Humans; Ketotifen; Mast C | 1983 |
Histamine antagonists and asthma.
Topics: Airway Resistance; Animals; Antigens; Asthma; Bronchi; Histamine Antagonists; Humans; Ketotifen; Lun | 1982 |
Ketotifen in childhood allergic disease.
Topics: Aging; Airway Obstruction; Animals; Asthma; Asthma, Exercise-Induced; Body Weight; Bronchial Provoca | 1982 |
Asthma in the very young.
Topics: Asthma; Child; Child, Preschool; Diagnosis, Differential; Humans; Ketotifen | 1995 |
Anti-allergic drug use in Japan--the rationale and the clinical outcome.
Topics: Administration, Oral; Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Histamine Antagonist | 1994 |
[Inhibitor of chemical mediator release].
Topics: Asthma; Clinical Trials as Topic; Depression, Chemical; Double-Blind Method; Histamine H1 Antagonist | 1996 |
[Antiallergy drugs and respiratory diseases in children].
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Child; Child, Preschoo | 1999 |
[Membrane stabilizers (chromones and ketotifen)].
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cell Membrane; Conjunctivitis; Cromoly | 1999 |
The problems of treating adolescent asthma: what are the alternatives to inhaled therapy?
Topics: Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Histamine H1 | 1999 |
Clinical use of antihistamines in infants and children at risk of asthma development.
Topics: Asthma; Cetirizine; Child, Preschool; Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Hy | 2000 |
Ketotifen.
Topics: Airway Resistance; Asthma; Bronchial Hyperreactivity; Child; Humans; Ketotifen | 1992 |
[Anti-asthmatic agents. From pharmacology to clinical aspects].
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Cromolyn Sodium; Glucocorticoids; Humans; K | 1991 |
[Treatment of asthma].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchodilator Agents; Combined Modality Therapy; C | 1990 |
Prophylaxis in childhood asthma.
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male | 1990 |
[Therapy of obstructive airway diseases. IV: medications with anti-allergic and anti-inflammatory action].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cromolyn Sodium; Humans; Ketotifen; Nedocromil; Qui | 1990 |
[Hypersensitivity of the respiratory tract: determination, occurrence and clinical significance].
Topics: Adrenal Cortex Hormones; Allergens; Asthma; Bronchitis; Chronic Disease; Humans; Ketotifen; Nedocrom | 1990 |
Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders.
Topics: Asthma; Bronchi; Humans; Hypersensitivity; Ketotifen; Platelet Activating Factor | 1990 |
[Zaditen: a pharmacologic and therapeutic profile].
Topics: Asthma; Histamine Release; Humans; Ketotifen | 1988 |
Metabisulfite sensitivity: case report and literature review.
Topics: Adult; Asthma; Female; Food Additives; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E | 1985 |
[Bronchial adrenergic receptors and asthma. Tachyphylaxis and its prevention].
Topics: Adrenal Cortex Hormones; Asthma; Bronchi; Humans; Ketotifen; Methacholine Chloride; Methacholine Com | 1988 |
Drug level monitoring of antiasthmatic drugs.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Chromatography; Cromolyn Sodium; Humans; | 1985 |
Asthma therapy: basic mechanisms.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Animals; Annexins; Asthma; Calcium; Capillary Per | 1986 |
Alternative drug therapy for asthma.
Topics: Adrenergic alpha-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Calcium Channel Block | 1986 |
Pharmacotherapy of allergic disease.
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Aged; Anaphylax | 1987 |
New concepts in bronchodilator therapy.
Topics: Adrenal Cortex Hormones; Asthma; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Fenotero | 1986 |
[Prophylaxis of bronchial asthma--disodium cromoglycate and ketotifen].
Topics: Asthma; Cromolyn Sodium; Humans; Ketotifen | 1987 |
[Ketotifen (Zaditen) and disodium cromoglycinic acid (Intal) in the therapy of bronchial asthma].
Topics: Animals; Asthma; Cromolyn Sodium; Humans; Ketotifen; Respiratory Hypersensitivity | 1987 |
Drugs for bronchial asthma.
Topics: Asthma; Cromolyn Sodium; Glucocorticoids; Humans; Ketotifen; Vasodilator Agents | 1988 |
[Zadeten in the treatment of allergic diseases in children].
Topics: Adolescent; Asthma; Child; Child, Preschool; Humans; Ketotifen | 1987 |
128 trials available for ketotifen and Asthma
| Article | Year |
|---|---|
[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children].
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Drug Combinati | 2019 |
Early intervention with suplatast tosilate for prophylaxis of pediatric atopic asthma: a pilot study.
Topics: Allergens; Animals; Anti-Allergic Agents; Arylsulfonates; Asthma; Chemoprevention; Dermatitis, Atopi | 2009 |
Prevention of recurrent wheezing in young children by loratadine compared with ketotifen.
Topics: Administration, Oral; Anti-Allergic Agents; Asthma; Child, Preschool; Double-Blind Method; Female; H | 2009 |
Ketotifen versus inhaled budesonide for controlling childhood asthma.
Topics: Administration, Inhalation; Adolescent; Anti-Allergic Agents; Asthma; Bronchodilator Agents; Budeson | 2010 |
Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chemokine CCL17; Chemokine CCL22; Chemokines; Chemokines, C | 2005 |
Regulation of stromal cell-derived factor-1 and exhaled nitric oxide in asthmatic children following montelukast and ketotifen treatment.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bud | 2007 |
Ketotifen in adult asthma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Albuterol; Asthma; Clinical Trials as Topic; Doubl | 1980 |
[Long-term therapy of bronchial asthma with ketotifen. European experiences].
Topics: Administration, Oral; Adult; Asthma; Child; Cromolyn Sodium; Drug Administration Schedule; Drug Eval | 1980 |
[Treatment of seasonal asthmatic symptoms. A multicentre trial to compare the effects of ketotifen and disodium cromoglycate (author's transl)].
Topics: Adrenergic beta-Agonists; Asthma; Beclomethasone; Bronchitis; Clinical Trials as Topic; Cromolyn Sod | 1980 |
The protective effect of ketotifen in bronchial asthma.
Topics: Asthma; Clinical Trials as Topic; Cromolyn Sodium; Female; Histamine H1 Antagonists; Humans; Ketotif | 1980 |
A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma.
Topics: Adolescent; Adult; Aged; Asthma; Cromolyn Sodium; Double-Blind Method; Drug Evaluation; Histamine H1 | 1980 |
A comparison between the efficacy of ketotifen and clemastine in children.
Topics: Asthma; Child; Child, Preschool; Clemastine; Dyspnea; Female; Histamine H1 Antagonists; Humans; Infa | 1980 |
[Therapeutic effect of Zaditen (Sandoz) in atopic bronchial asthma].
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Histamine H | 1980 |
[Experience in using a zaditen preparation in the therapy of bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Bronchitis; Capsules; Clinical Trials as Topic; Double-Blind Method | 1981 |
Long-term study of the protective effect of ketotifen in children with allergic bronchial asthma. The value of a provocation test in assessment of treatment.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Cromolyn Sodium; Follow-Up | 1981 |
Ketotifen in atopic asthma and exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Double-Blind M | 1981 |
Ketotifen: a new drug for prophylaxis of asthma in children.
Topics: Acute Disease; Asthma; Blood Pressure; Body Weight; Child; Chronic Disease; Clinical Trials as Topic | 1982 |
[Ketotifen in the prevention of bronchial asthma. International therapeutic evaluation].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Asthma; Bronchial Provocation Tests; Bronchodilator Age | 1981 |
[Effectiveness of the use of zaditen in allergic dermatoses and the dermorespiratory syndrome in children].
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Histamine H1 Antagoni | 1983 |
A comparison of ketotifen with clemastine, ipratropium bromide and sodium cromoglycate in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Atropine Derivatives; Child; Clemastine; Cromol | 1982 |
Clinical trial of ketotifen in Thai adult asthmatics.
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Female; Humans; Ketotifen; Male; Middle Aged; T | 1983 |
A controlled comparison of slow-release theophylline, ketotifen and placebo in the prophylaxis of asthma in young children.
Topics: Administration, Oral; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Delayed-Action Prep | 1983 |
[Long-term treatment of bronchial asthma with ketotifen. Relation to bronchial hyperirritability].
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Clinical Trials as Topic; Double-Blin | 1983 |
The prophylactic treatment of bronchial asthma in children with ketotifen: a double-blind comparison with placebo.
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Keto | 1983 |
Ketotifen and nocturnal asthma.
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Fe | 1983 |
[Clinical evaluation of Zaditen syrup in the treatment of children with bronchial asthma].
Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Clinical Trials as Topic; Double-Blind Method; Fem | 1983 |
Double-blind comparisons of slow-release theophylline, ketotifen and placebo for prophylaxis of asthma in young children.
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind | 1984 |
The effect of ketotifen on the in vitro immune function of asthmatic children.
Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Female; Humans; Immune System; Ketotifen; Lymph | 1983 |
A clinical trial of ketotifen in Thai asthmatics.
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Female; Humans; Hypersensitivity; Ketotifen; Ma | 1983 |
Inverse relation between peak expiratory flow rate (PEFR) and duration of attacks in asthmatics undergoing therapy with Ketotifen.
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Female; Forced Expiratory Flow Rates; Hu | 1984 |
Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Double-Blind Method; Humans; Ketotife | 1983 |
Prophylaxis of asthma with ketotifen in children and adolescents: a review.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Clemastine; Clinical Trial | 1983 |
The effect of ketotifen on aspirin-induced asthmatic reactions.
Topics: Adult; Aged; Aspirin; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Drug H | 1983 |
A double-blind comparison of ketotifen and disodium cromoglycate in atopic adult asthmatics.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-B | 1983 |
Effect of oral sodium cromoglycate and ketotifen in fish-induced bronchial asthma.
Topics: Adult; Allergens; Animals; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; F | 1983 |
Evaluation of ketotifen (HC20-511) in bronchial asthma.
Topics: Adolescent; Adult; Aerosols; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; | 1983 |
Long term trial of ketotifen in bronchial asthma.
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Child; Clinical Trials as Topic; Dose-Response R | 1984 |
Oral prophylaxis of bronchial asthma in children.
Topics: Administration, Oral; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Inf | 1984 |
Use of calcium channel blocking agents in the management of childhood asthma.
Topics: Adolescent; Adult; Age Factors; Asthma; Bronchial Provocation Tests; Calcium; Calcium Channel Blocke | 1984 |
The influence of ketotifen and aminophylline on the central and peripheral airways.
Topics: Adult; Aged; Aminophylline; Asthma; Double-Blind Method; Female; Humans; Ketotifen; Lung Diseases, O | 1983 |
[Ketotifen (Zaditen) in the treatment of bronchial asthma].
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Female; Humans; Ketotifen; Male; Middle | 1982 |
A comparative study of the prophylactic effect of ketotifen and sodium cromoglycate in children with pollen-induced asthma.
Topics: Asthma; Child; Cromolyn Sodium; Double-Blind Method; Humans; Ketotifen; Piperidines; Pollen; Thiophe | 1980 |
Clinical evaluation of a new orally active anti-anaphylactic compound: ketotifen (HC 20-511) in Japanese adult asthmatics.
Topics: Adult; Anaphylaxis; Asthma; Basophils; Cromolyn Sodium; Double-Blind Method; Humans; Hypersensitivit | 1980 |
Ketotifen in bronchial asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Humans; Ketotifen; Middle Aged; Pipe | 1980 |
Double-blind study comparing ketotifen and DSCG in adolsecent asthmatics.
Topics: Adolescent; Asthma; Cromolyn Sodium; Double-Blind Method; Humans; Ketotifen; Piperidines; Thiophenes | 1980 |
Comparison of ketotifen, disodium cromoglycate and placebo in the treatment of adult patients with extrinsic asthma.
Topics: Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Humans; Ketotifen; Peak Expiratory Flow Ra | 1980 |
Ketotifen versus sodium cromoglycate in the therapy of allergic (extrinsic) bronchial asthma.
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Humans; Ketotifen; Middle Aged | 1980 |
Comparison of the clinical effect of ketotifen and DSCG in pollen-induced childhood asthma.
Topics: Adolescent; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Cromolyn Sodium; Desensitizat | 1980 |
[Protective effect of ketotifen and disodium cromoglycate in bronchial challenge tests with allergens (author's transl)].
Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Dust; Fem | 1980 |
A controlled trial of ketotifen in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Doub | 1980 |
Ketotifen and asthma.
Topics: Adult; Animals; Asthma; Child; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Human | 1981 |
Comparison of ketotifen, disodium cromoglycate and placebo in the treatment of adult patients with mild extrinsic asthma.
Topics: Adult; Albuterol; Asthma; Circadian Rhythm; Cromolyn Sodium; Female; Humans; Ketotifen; Male; Middle | 1981 |
[Prophylactic treatment of exercise-induced asthma].
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Child; Child, Preschool; Cromol | 1981 |
A double-blind trial comparing disodium cromoglycate (DSCG), and ketotifen in extrinsic asthmatic children.
Topics: Adolescent; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind | 1981 |
Comparison of the orally administered anti-allergy agent, ketotifen with sodium cromoglycate in the prophylaxis of bronchial asthma.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Dose-Res | 1981 |
Therapeutic modulation of bronchial hyperreactivity.
Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Human | 1982 |
Ketotifen in childhood allergic disease.
Topics: Aging; Airway Obstruction; Animals; Asthma; Asthma, Exercise-Induced; Body Weight; Bronchial Provoca | 1982 |
[Drug prevention of allergic bronchial asthma. Comparison of the protective effects of ketotifen and cromoglycic acid].
Topics: Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ketot | 1982 |
A double-blind clinical trial of ketotifen and disodium cromoglycate in bronchial asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Cough; Cromolyn Sodium; Double-Blind Method; Dyspnea; | 1982 |
Ketotifen in adult asthma.
Topics: Aminophylline; Asthma; Clinical Trials as Topic; Humans; Ketotifen; Lung Volume Measurements; Piperi | 1980 |
Ketotifen in the prophylaxis of childhood asthma.
Topics: Asthma; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Ket | 1981 |
[Methods employed in the post-marketing surveillance of an oral agent for asthma-prophylaxis (author's transl)].
Topics: Administration, Oral; Asthma; Clinical Trials as Topic; Humans; Ketotifen; Piperidines; Thiophenes | 1981 |
A trial of ketotifen in intrinsic asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Female; Humans; Ketotifen; Male; Middle Aged | 1981 |
A double blind placebo controlled study on the use of ketotifen in childhood asthma.
Topics: Asthma; Child; Child, Preschool; Double-Blind Method; Female; Humans; Ketotifen; Male; Placebos | 1982 |
[Ketotifen in the prophylactic treatment of children with pollen asthma during flowering time].
Topics: Asthma; Child; Female; Humans; Ketotifen; Male; Rhinitis, Allergic, Seasonal | 1982 |
[Ketotifene in asthma in childhood].
Topics: Asthma; Child; Humans; Ketotifen; Piperidines; Thiophenes | 1980 |
Zaditen SRO permits once-daily dosing with superior efficacy in the prophylaxis of asthma.
Topics: Adolescent; Adult; Asthma; Child; Delayed-Action Preparations; Double-Blind Method; Drug Administrat | 1995 |
A double-blind, placebo-controlled comparison of sodium cromoglycate and ketotifen in the treatment of childhood asthma.
Topics: Administration, Oral; Adolescent; Adult; Aerosols; Asthma; Child; Cromolyn Sodium; Double-Blind Meth | 1995 |
Prevention of asthma with ketotifen in preasthmatic children: a three-year follow-up study.
Topics: Asthma; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Ketotifen; | 1995 |
Parental perceptions and attitudes about informed consent in clinical research involving children.
Topics: Adult; Asthma; Attitude to Health; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; | 1995 |
The Japanese perspective: effects of terfenadine in bronchial asthma: in vitro and in vivo research.
Topics: Adult; Airway Resistance; Animals; Asthma; Female; Guinea Pigs; Histamine Release; Humans; Japan; Ke | 1993 |
Administration of half-dose theophylline together with ketotifen to asthmatic children--a double-blind, placebo-controlled study.
Topics: Asthma; Child; Child Behavior; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combi | 1994 |
Transcutaneous O2 and CO2 monitoring of bronchial responsiveness in FEV1 non-responder asthmatics during ketotifen and placebo treatment.
Topics: Adult; Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Provocation Tests; Carbon Dioxide; Fe | 1993 |
[DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma].
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Airway Resistance; Asthma; Asth | 1993 |
Multicenter study with ketotifen (Zaditen) oral drop solution in the treatment of wheezy children aged 6 months to 3 years.
Topics: Asthma; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Ketotifen; | 1993 |
Parental perceptions and attitudes about informed consent in clinical research involving children.
Topics: Administration, Oral; Anti-Allergic Agents; Asthma; Attitude; Australia; Child; Child, Preschool; Cl | 1995 |
Does ketotifen have a steroid-sparing effect in childhood asthma?
Topics: Administration, Inhalation; Administration, Topical; Adolescent; Adrenergic beta-Agonists; Anti-Asth | 1997 |
Ketotifen pharmacokinetics in children with atopic perennial asthma.
Topics: Anti-Allergic Agents; Asthma; Child; Child, Preschool; Double-Blind Method; Humans; Hypersensitivity | 1997 |
Effects of ketotifen on symptoms and on bronchial mucosa in patients with atopic asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Anti-Allergic Agents; Antigens, CD; Antineoplastic Comb | 1997 |
[Clinical study on jianfei pill in preventing and treating recurrence of infantile asthma].
Topics: Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Drugs, Chinese Herbal; Female; Histamine H1 | 1997 |
A comparative study of the effects of ketotifen, disodium cromoglycate, and beclomethasone dipropionate on bronchial mucosa and asthma symptoms in patients with atopic asthma.
Topics: Adolescent; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchi; | 1998 |
Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial.
Topics: Adolescent; Anti-Allergic Agents; Asthma; Child; Child, Preschool; Cough; Dose-Response Relationship | 2000 |
[Ketotifen, a new prophylactic agent in asthma (author's transl)].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Asthma; Child; Female; Humans; Ketotifen; Male | 1979 |
[Usefulness of salmeterol in nocturnal asthma: a comparative study with theophylline-ketotifen association. A French multicenter group].
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Double-Blind Method; Drug Ther | 1992 |
Salmeterol versus slow-release theophylline combined with ketotifen in nocturnal asthma: a multicentre trial. French Multicentre Study Group.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Albuterol; Asthma; Bronch | 1992 |
Prevention of asthma by ketotifen in infants with atopic dermatitis.
Topics: Asthma; Child, Preschool; Dermatitis, Atopic; Dose-Response Relationship, Drug; Double-Blind Method; | 1992 |
Allergen-induced increase in airway responsiveness is not inhibited by acute treatment with ketotifen or clemastine.
Topics: Adult; Airway Resistance; Allergens; Analysis of Variance; Asthma; Clemastine; Cromolyn Sodium; Dose | 1992 |
Clinical trial with ketotifen.
Topics: Asthma; Humans; Ketotifen | 1991 |
Lens safety study with Picumast dihydrochloride--a double masked study using the Scheimpflug method.
Topics: Asthma; Cataract; Coumarins; Densitometry; Double-Blind Method; Histamine H1 Antagonists; Humans; Ke | 1990 |
[A double blind study of the effectiveness of ketotifen in preventing the development of asthma in atopic dermatitis patients].
Topics: Age Factors; Asthma; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Humans; Infant; Keto | 1991 |
Pulmonary function parameters in asthma patients receiving oral ketotifen.
Topics: Administration, Oral; Adult; Asthma; Female; Forced Expiratory Volume; Humans; Ketotifen; Male; Peak | 1990 |
Ketotifen for long-term control of asthma in children.
Topics: Adolescent; Asthma; Child; Child, Preschool; Humans; Ketotifen; Multicenter Studies as Topic; Resear | 1990 |
Effect of ketotifen on childhood asthma: a double-blind study.
Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Clinical Trials as Topic; Double | 1990 |
Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects.
Topics: Asthma; Cyanates; Double-Blind Method; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; | 1989 |
A one-year double-blind clinical study of the efficacy and tolerability of picumast dihydrochloride versus ketotifen in patients with bronchial asthma.
Topics: Adult; Asthma; Coumarins; Double-Blind Method; Female; Forced Expiratory Volume; Histamine H1 Antago | 1989 |
Ketotifen in asthma.
Topics: Asthma; Child; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Hum | 1989 |
A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years.
Topics: Adolescent; Asthma; Bronchospirometry; Canada; Child; Child, Preschool; Clinical Trials as Topic; Do | 1989 |
Ketotifen in the prophylaxis of extrinsic bronchial asthma. A multicenter controlled double-blind study with a modified-release formulation.
Topics: Adolescent; Adult; Asthma; Child; Delayed-Action Preparations; Double-Blind Method; Drug Administrat | 1989 |
[Therapy with ketotifen in breast-fed infants with asthma].
Topics: Asthma; Bronchodilator Agents; Drug Evaluation; Female; Humans; Infant; Infant, Newborn; Ketotifen; | 1989 |
Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma.
Topics: Adolescent; Airway Resistance; Asthma; Bronchi; Child; Female; Humans; Immunoglobulin E; Iodocyanopi | 1988 |
The effects of ketotifen on beta-adrenergic activity in asthmatics.
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Blood Glucose; Double-Blind Method; Female; Humans; Ipra | 1988 |
[Bronchial adrenergic receptors and asthma. Tachyphylaxis and its prevention].
Topics: Adrenal Cortex Hormones; Asthma; Bronchi; Humans; Ketotifen; Methacholine Chloride; Methacholine Com | 1988 |
Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Chemotaxis, Leukocyte; Clemastine; Cromolyn S | 1985 |
The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histamine; Histamine H1 Ant | 1987 |
[Experience with ketotifen in respiratory tract diseases].
Topics: Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Ketotifen; Rhinitis, Allergic, Perenn | 1986 |
[Use of ketotifen in allergic bronchial asthma].
Topics: Adult; Asthma; Clinical Trials as Topic; Female; Humans; Ketotifen; Male; Random Allocation; Seasons | 1987 |
Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Double-Blind Method; Female; F | 1987 |
Long-term, placebo-controlled trial of ketotifen in the management of preschool children with asthma.
Topics: Asthma; Child, Preschool; Humans; Ketotifen | 1988 |
Effect of ketotifen on the bronchodilation induced by salbutamol.
Topics: Adult; Albuterol; Asthma; Bronchi; Dilatation, Pathologic; Female; Forced Expiratory Volume; Humans; | 1988 |
Efficacy and safety of ketotifen in young children with asthma.
Topics: Asthma; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Ket | 1988 |
[Effect of prolonged administration of ketotifen on bronchial reactivity and the medication of asthma patients].
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; | 1986 |
Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation?
Topics: Adult; Asthma; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expira | 1987 |
[Role of ketotifen in the immunotherapy of atopic asthmatics].
Topics: Adolescent; Adult; Animals; Asthma; Child; Child, Preschool; Desensitization, Immunologic; Dust; Fem | 1986 |
The use of ketotifen in the prophylaxis of seasonal allergic asthma.
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Double-Blind Method; Humans; Ketotifen; | 1986 |
Ketotifen in pollen-induced asthma: a double blind placebo-controlled study.
Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketotifen; | 1986 |
Effect of ketotifen on the bronchodilating action of aminophylline.
Topics: Adolescent; Adult; Aminophylline; Asthma; Bronchi; Clinical Trials as Topic; Double-Blind Method; Dr | 1986 |
Ketotifen in the treatment of infants and young children with wheezy bronchitis and bronchial asthma.
Topics: Asthma; Bronchitis; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Ketotifen; Respirato | 1986 |
Long-term, placebo-controlled trial of ketotifen in the management of preschool children with asthma.
Topics: Asthma; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Ket | 1987 |
Non-interaction of ketotifen and theophylline in children with asthma--an acute study.
Topics: Adolescent; Asthma; Child; Drug Interactions; Half-Life; Hemodynamics; Humans; Ketotifen; Respirator | 1987 |
The effect of ketotifen on bronchial hyperreactivity in childhood asthma.
Topics: Adolescent; Asthma; Bronchial Spasm; Child; Female; Humans; Ketotifen; Male; Methacholine Chloride; | 1985 |
[Zaditen in the treatment of atopic bronchial asthma in adults].
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketotifen; Male | 1985 |
Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, D | 1985 |
A multicenter trial of the prophylactic effect of ketotifen, theophylline, and placebo in atopic asthma.
Topics: Adolescent; Asthma; Clinical Trials as Topic; Female; Humans; Hypersensitivity, Immediate; Ketotifen | 1985 |
Ketotifen and asthma.
Topics: Asthma; Child; Clinical Trials as Topic; Humans; Ketotifen | 1985 |
Long-term modification on histamine-induced bronchoconstriction by disodium cromoglycate and ketotifen versus placebo.
Topics: Adolescent; Adult; Asthma; Bronchi; Cromolyn Sodium; Female; Forced Expiratory Volume; Histamine; Hu | 1985 |
[Comparative evaluation of the effects of sodium cromoglycate and ketotifen on exercise-induced bronchospasm in patients with asthma].
Topics: Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Female; Humans; | 1985 |
A multicenter study with ketotifen (Zaditen).
Topics: Administration, Oral; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Forced | 1985 |
Effect of Zaditen on serum neutrophil chemotactic activity in exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Humans; Ketotifen; Neutrophils; Premed | 1985 |
168 other studies available for ketotifen and Asthma
| Article | Year |
|---|---|
Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application i
Topics: Animals; Asthma; Female; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lipoxygenase Inhib | 1995 |
Development of a Carrier Free Dry Powder Inhalation Formulation of Ketotifen for Pulmonary Drug Delivery.
Topics: Administration, Inhalation; Aerosols; Asthma; Chemistry, Pharmaceutical; Drug Compounding; Dry Powde | 2020 |
Ketotifen use in a patient with fire ant hypersensitivity and mast cell activation syndrome.
Topics: Adult; Anaphylaxis; Animals; Ant Venoms; Anti-Allergic Agents; Ants; Asthma; Erythema; Female; Hista | 2015 |
Phytopharmacological evaluation and anti-asthmatic activity of Ficus religiosa leaves.
Topics: Acetylcholine; Aminophylline; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bronchia | 2011 |
The use of anti-asthmatic medications among pediatric patients in Taiwan.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic be | 2003 |
Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Cerebral Cortex; Dexamethasone; Female; Histamine H1 Anta | 2003 |
Identifying children with persistent asthma from health care administrative records.
Topics: Adolescent; Adrenergic beta-Agonists; Anti-Allergic Agents; Asthma; Bronchitis; Canada; Child; Child | 2004 |
Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Asthma; Cerebral Cortex; Dexamethaso | 2005 |
Suppression of plasma matrix metalloproteinase-9 following montelukast treatment in childhood asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Cyclopropanes; Female; His | 2007 |
Development and characterisation of a novel and rapid lung eosinophil influx model in the rat.
Topics: Alum Compounds; Aminopyridines; Animals; Anti-Inflammatory Agents; Asthma; Benzamides; Bronchoalveol | 2008 |
[Ketotifen in the therapy of bronchial asthma].
Topics: Adult; Asthma; Bronchial Provocation Tests; Child; Drug Evaluation; Histamine Release; Humans; Ion C | 1984 |
[Ketotifen--a new anti-asthma drug].
Topics: Asthma; Bronchodilator Agents; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Histamin | 1980 |
Inhibition by ketotifen of idiosyncratic reactions to aspirin.
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; Histamine H1 Antago | 1980 |
[Risk evaluation and management of the pregnant asthmatic].
Topics: Adrenergic beta-Agonists; Asthma; Cromolyn Sodium; Female; Humans; Hydrocortisone; Ketotifen; Pregna | 1982 |
Factorial rating system for comparative efficacy of antiasthmatic medication: a multicentric study report.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aerosols; Asthma; Evaluatio | 1983 |
Asthma therapy. Advantages and limitations of various approaches.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Calcium Channel Blockers; | 1983 |
[Bronchial asthma. Advances].
Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cromol | 1983 |
Airway hyperreactivity. Clinical treatment with drugs.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchial Provocation Test | 1983 |
Other pharmacologic agents that may affect bronchial hyperreactivity.
Topics: Adrenergic alpha-Antagonists; Asthma; Asthma, Exercise-Induced; Benzothiazoles; Budesonide; Calcium | 1984 |
Antiasthmatic effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidaz ole difumarate (KB-2413), a new antiallergic.
Topics: Airway Resistance; Anaphylaxis; Animals; Asthma; Benzimidazoles; Chlorpheniramine; Guinea Pigs; Hist | 1984 |
Mast cell mediators in asthma. Clinical uses of the inhibitors.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Child; Child, Preschool; Cromolyn Sodium; Cytopl | 1981 |
Ketotifen: current views on its mechanism of action and their therapeutic implications.
Topics: Animals; Asthma; Bronchial Spasm; Guinea Pigs; Histamine Release; Humans; In Vitro Techniques; Ketot | 1984 |
[Asthma therapy in medical practice].
Topics: Adrenal Cortex Hormones; Asthma; Cephalosporins; Cromolyn Sodium; Expectorants; Humans; Ipratropium; | 1982 |
[Clinico-experimental possibilities in asthma].
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Cromolyn Sodium; Drug Evaluation; Hum | 1984 |
Modulation of the beta-adrenergic system: possible implications for the prophylactic action of ketotifen in asthma.
Topics: Adenylyl Cyclases; Animals; Asthma; Ketotifen; Rats; Receptors, Adrenergic; Receptors, Adrenergic, a | 1982 |
[Mediator disorders in atopic bronchial asthma in children, and problems of therapy].
Topics: Adenylyl Cyclases; Aminophylline; Asthma; Child; Child, Preschool; Cyclic AMP; Humans; Ketotifen; Pr | 1983 |
Main mechanisms of therapeutic action in atopic asthma in children.
Topics: Aminophylline; Asthma; B-Lymphocytes; Child; Child, Preschool; Cromolyn Sodium; Cyclic AMP; Desensit | 1983 |
Antigen bronchial challenge and efficacy after 4 weeks of treatment with ketotifen and disodium cromoglycate.
Topics: Adolescent; Adult; Antigens; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Double-Blind Meth | 1983 |
[Rational asthma drug therapy].
Topics: Aminophylline; Anti-Bacterial Agents; Asthma; Bronchial Spasm; Cromolyn Sodium; Desensitization, Imm | 1983 |
Prophylactic drugs in asthma.
Topics: Asthma; Cromolyn Sodium; Humans; Ketotifen | 1983 |
[Comparative evaluation of the effectiveness of sodium cromoglycate and ketotifen in bronchial asthma and their effect on blood histamine and polymyxin-induced bronchial spasm].
Topics: Asthma; Bronchial Spasm; Cromolyn Sodium; Female; Histamine; Humans; Ketotifen; Male; Polymyxin B | 1983 |
Postmarketing surveillance: practical experience with ketotifen.
Topics: Adolescent; Adult; Aged; Asthma; Child; Communication; Evaluation Studies as Topic; Female; Humans; | 1984 |
Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Clemastine; Cromolyn Sodium; Double- | 1984 |
A comparison of the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses to house dust, with special reference to the late asthmatic response.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cromolyn Sodium; Dust; Female; Huma | 1984 |
Use of inhaled calcium channel blocking agents in the treatment of asthma.
Topics: Aerosols; Airway Resistance; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Test | 1984 |
Clinical effects of HC 20-511 (ketotifen) in bronchial asthma and its inhibitory effect on antigen-induced morphological changes of basophils.
Topics: Adolescent; Adult; Allergens; Asthma; Basophils; Female; Humans; Immunoglobulin E; Ketotifen; Male; | 1980 |
[Ketotifen as prophylaxis in childhood bronchial asthma].
Topics: Asthma; Child; Child, Preschool; Humans; Infant; Ketotifen | 1984 |
[Personal experience in the prevention of asthma in children using ketotifen].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen | 1984 |
[Long-term treatment with ketotifen and levels of growth hormone in children].
Topics: Asthma; Blood Glucose; Child, Preschool; Female; Growth Hormone; Humans; Ketotifen; Male; Respirator | 1984 |
Inhibition of eosinophils degranulation by Ketotifen in a patient with milk allergy, manifested as bronchial asthma--an electron microscopic study.
Topics: Adult; Animals; Asthma; Cattle; Cytoplasmic Granules; Diagnosis, Differential; Eosinophils; Food Hyp | 1984 |
[Effect of ketotifen (zaditen) on the clinical course of bronchial asthma and obstructive bronchitis in children].
Topics: Asthma; Bronchitis; Child; Child, Preschool; Female; Humans; Infant; Ketotifen; Male | 1984 |
Effects of ketotifen on cholinergic induced airway obstruction.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Doubl | 1983 |
[Clinical study of the preventive action of ketotifen in children with allergic diseases].
Topics: Asthma; Child; Child, Preschool; Dermatitis, Atopic; Eczema; Humans; Hypersensitivity; Infant; Ketot | 1983 |
[Acute effect of ketotifen on non-specific bronchial reactivity in asthma].
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Female; Humans; Ketotifen; Male; Middl | 1983 |
[Immunologic indices in evaluation of the effectiveness of treatment of atopic bronchial asthma in children].
Topics: Asthma; Child; Child, Preschool; Desensitization, Immunologic; Humans; Hypersensitivity, Immediate; | 1983 |
Ketotifen in African children.
Topics: Africa; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male | 1983 |
[Clinical study of an oral solution of ketotifen in children. Preliminary results of 257 cases].
Topics: Administration, Oral; Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male | 1984 |
Growth hormone plasma levels in children treated for 6 months with ketotifen.
Topics: Adolescent; Asthma; Blood Glucose; Body Height; Body Weight; Child; Female; Glucose Tolerance Test; | 1984 |
Influence of ketotifen on the airway responsiveness in asthmatics.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Dose-Response Rel | 1984 |
[Ketotifen in the treatment of hypersensitivity to acetylsalicylic acid].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Ketotifen; Male; Middle Aged | 1984 |
[Effect of Zaditen in patients with atopic bronchial asthma at Sandanski health resort].
Topics: Adolescent; Adult; Asthma; Bulgaria; Chronic Disease; Climate; Drug Evaluation; Drug Therapy, Combin | 1984 |
[Ketotifene: experimental and clinical data].
Topics: Administration, Oral; Animals; Asthma; Binding, Competitive; Cromolyn Sodium; Histamine Antagonists; | 1980 |
[Ketotiphen (Zaditen) in the treatment of asthma].
Topics: Adolescent; Adult; Asthma; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ketotifen; Male; Mi | 1980 |
Ketotifen, an anti-allergic drug. Pharmacological figures anc clinical experience.
Topics: Asthma; Cromolyn Sodium; Humans; Hypersensitivity; Ketotifen; Piperidines; Thiophenes | 1980 |
Comparison of actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction in childhood asthma.
Topics: Asthma; Asthma, Exercise-Induced; Child; Cromolyn Sodium; Humans; Ketotifen; Piperidines; Thiophenes | 1980 |
A steroid sparing effect of ketotifen in steroid-dependent asthmatics.
Topics: Adult; Aged; Anaphylaxis; Asthma; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ketotifen; M | 1980 |
Actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction.
Topics: Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Humans; Ketotifen; Piperidines; Thiophenes | 1981 |
Drugs for asthma: mast-cell stabilisers.
Topics: Asthma; Cromolyn Sodium; Humans; Ketotifen; Mast Cells; Piperidines; Thiophenes | 1981 |
Contemporary problems of epidemiology and treatment of respiratory allergies and bronchial asthma.
Topics: Adult; Asthma; Bacterial Vaccines; Cromolyn Sodium; Desensitization, Immunologic; Humans; Ketotifen; | 1980 |
[Bronchial asthma in children].
Topics: Adrenal Cortex Hormones; Asthma; Child; Cromolyn Sodium; Desensitization, Immunologic; Humans; Ketot | 1982 |
[Asthma and rhinitis induced by the ingestion of pure ethanol and by the inhalation of alcohol vapors].
Topics: Adult; Alcohol Drinking; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Ethanol; Female; Huma | 1982 |
An overview of ketotifen.
Topics: Asthma; Cromolyn Sodium; Humans; Ketotifen | 1982 |
Pharmacological rehabilitation of the asthmatic child.
Topics: Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Child; Cromolyn Sodium; Huma | 1981 |
Ketotifen in childhood asthma.
Topics: Adult; Asthma; Child; Drug Administration Schedule; Humans; Ketotifen | 1983 |
Ketotifen in treatment of asthmatic children.
Topics: Adolescent; Asthma; Child; Drug Evaluation; Female; Humans; Ketotifen; Male | 1982 |
Refractory period to aspirin after aspirin-induced asthma.
Topics: Aspirin; Asthma; Humans; Ketotifen | 1982 |
Ketotifen in the prophylaxis of bronchial asthma.
Topics: Asthma; Bronchi; Humans; Ketotifen; Nasal Mucosa; Skin Tests | 1982 |
[Prevention of bronchial asthma in children with ketotifen].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Infant; Ketotifen; Male | 1982 |
[Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)].
Topics: Administration, Topical; Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cough; | 1980 |
Ketotifen and bronchial hyperreactivity in asthmatic patients.
Topics: Acetylcholine; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expirator | 1981 |
[Hyperventilation test in the diagnosis of bronchial asthma (author's transl)].
Topics: Adolescent; Adult; Airway Resistance; Asthma; Female; Humans; Hyperventilation; Ketotifen; Male; Mid | 1981 |
Ketotifen in adult asthma.
Topics: Adult; Asthma; Humans; Ketotifen; Piperidines; Sleep Stages; Thiophenes | 1980 |
Ketotifen in adult asthma.
Topics: Adult; Asthma; Humans; Ketotifen; Piperidines; Sleep Stages; Thiophenes | 1980 |
Oral prophylaxis of bronchial asthma in children.
Topics: Administration, Oral; Asthma; Blood Pressure; Child; Child, Preschool; Double-Blind Method; Humans; | 1980 |
Inhibition of idiosyncratic reactions to aspirin by ketotifen.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Ketotifen; Piperidines; Thio | 1980 |
[Our experience with the preparation ketotiphen (author's transl)].
Topics: Adolescent; Adult; Asthma; Female; Humans; Ketotifen; Male; Middle Aged; Piperidines; Thiophenes | 1980 |
Aftercare for participants in clinical research: ethical considerations in an asthma drug trial.
Topics: Aftercare; Anti-Allergic Agents; Asthma; Australia; Compensation and Redress; Comprehension; Ethics, | 1995 |
Effects of various drugs (staurosporine, herbimycin A, ketotifen, theophylline, FK506 and cyclosporin A) on eosinophil viability.
Topics: Alkaloids; Asthma; Benzoquinones; Cell Survival; Cyclosporine; Eosinophils; Humans; Ketotifen; Lacta | 1994 |
Management of childhood and adolescent asthma. 1994 consensus. South African Childhood Asthma Working Group.
Topics: Adolescent; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child; Cromolyn Sodium; Humans; | 1994 |
[Evaluation of the impact of a care program for asthmatic children on the quality of anti-asthma drug prescriptions].
Topics: Administration, Inhalation; Administration, Oral; Administration, Rectal; Adolescent; Age Factors; A | 1995 |
Differential effects of anti-asthmatic drugs on arachidonic acid and platelet-activating factor.
Topics: Albuterol; Aminophylline; Arachidonic Acid; Asthma; Blood Platelets; Bronchodilator Agents; Humans; | 1994 |
[Status epilepticus in an asthmatic child].
Topics: Asthma; Bronchodilator Agents; Child, Preschool; Drug Therapy, Combination; Humans; Ketotifen; Male; | 1994 |
Ipratropium, sodium cromoglycate and antihistamines.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Child; Cromolyn Sodium; Histamine H1 Antagonists; Humans; | 1995 |
Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes.
Topics: Asthma; Calcimycin; Dibenzazepines; Histamine H1 Antagonists; Humans; Hypersensitivity; Imidazoles; | 1995 |
[The effect of ketotifen on the inflammation of bronchial mucosa in atopic asthmatics].
Topics: Adult; Asthma; Bronchi; Eosinophils; Female; Humans; Inflammation; Ketotifen; Male; Mucous Membrane; | 1994 |
[Treatment of asthma: estimation of the cost of adverse effects associated with ketotifen].
Topics: Asthma; Humans; Ketotifen; Prospective Studies | 1994 |
Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study.
Topics: Adolescent; Adult; Aged; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Te | 1993 |
Role of ketotifen in bronchial asthma.
Topics: Age Factors; Anti-Asthmatic Agents; Asthma; Child; Cromolyn Sodium; Histamine H1 Antagonists; Humans | 1996 |
[Antiallergic effects of a novel compound, SWR-00151].
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Cells, Cultured; Depression, Chemical; D | 1997 |
Ketotifen inhibits allergen-specific T lymphocytes' responses by suppressing antigen presentation with concomitant decrease of HLA-DQ antigen on macrophages.
Topics: Adolescent; Adult; Anti-Allergic Agents; Antigen Presentation; Asthma; Cell Adhesion; Cells, Culture | 1996 |
[Agranulocytosis induced by ketotifen].
Topics: Adult; Agranulocytosis; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Female; Humans; Hyperse | 1997 |
Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Disease Models, Animal; Eosinophilia; Eo | 1998 |
[In focus: Standard combination in asthma therapy. RPR-Press Conversation at the 40th Congress of the German Society for Pneumonology, Bad Reichenhall, 19 March 1999].
Topics: Anti-Allergic Agents; Asthma; Bronchodilator Agents; Drug Combinations; Humans; Ketotifen; Metaprote | 1999 |
Role of Ketotifen in asthma.
Topics: Asthma; Child, Preschool; Guidelines as Topic; Histamine H1 Antagonists; Humans; Infant; Ketotifen; | 1999 |
[Changes in biochemical inflammation markers in evaluation of the effectiveness of basic chemotherapy in bronchial asthma].
Topics: Adolescent; Adult; Age Factors; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Ast | 2001 |
Short-term effect of ketotifen on sputum physicochemical characteristics in chronic reversible airway disease.
Topics: Adult; Aged; Asthma; Double-Blind Method; Female; Humans; Ketotifen; Male; Middle Aged; Piperidines; | 1979 |
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui | 1992 |
[Effect of ketotifen, nedocromil sodium and budesonide on non-specific bronchial hyperreactivity to histamine in patients with asthma].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Provocation Tests; Bronchodilator | 1992 |
[Drug therapy of asthma by antiallergic agents].
Topics: Asthma; Cromolyn Sodium; Histamine Antagonists; Humans; Ketotifen; ortho-Aminobenzoates; Phthalazine | 1992 |
[Effect of ketotifen on the eicosanoid system, immunoreactivity and bronchial patency in patients with obstructive pulmonary diseases].
Topics: Adult; Asthma; Bronchi; Bronchitis; Bronchoalveolar Lavage Fluid; Chronic Disease; Eicosanoids; Epop | 1991 |
[Food hypersensitivities and asthma improved by ketotifen therapy].
Topics: Asthma; Child; Female; Food Hypersensitivity; Humans; Ketotifen | 1991 |
Mechanism of ketotifen action in hypersensitivity reactions. Its effect on cellular enzymatic activities.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Asthma; Calcium; Humans; In Vitro Techniques | 1991 |
Effects of the new antiallergic drug epinastine and ketotifen on repeated antigen challenge-induced airway hyperresponsiveness in rats.
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Asthma; Bronchial Hyperreactivity; Dibenzazepin | 1991 |
Effect of ketotifen on the reactivity of eosinophils with the incubation of anti-IgG.
Topics: Adolescent; Adult; Antibodies, Anti-Idiotypic; Asthma; Eosinophils; Humans; Immunoglobulin G; Ketoti | 1990 |
[Chemical mediators and anti-mediator drugs].
Topics: Asthma; Chemotactic Factors, Eosinophil; Cromolyn Sodium; Cytokines; Depression, Chemical; Histamine | 1991 |
[Clinical role of antiallergic drugs in the treatment for bronchial asthma].
Topics: Administration, Inhalation; Administration, Oral; Asthma; Cromolyn Sodium; Humans; Ketotifen | 1991 |
Effects of ketotifen and clenbuterol on beta-adrenergic receptor functions of lymphocytes and on plasma TXB-2 levels of asthmatic patients.
Topics: Asthma; Clenbuterol; Cyclic AMP; Drug Therapy, Combination; Humans; Ketotifen; Lymphocytes; Receptor | 1990 |
Inhibitory effect of HSR-6071, a new anti-allergic agent, on experimental asthma in rats and guinea-pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Animals; Asthma; Azoles; Bronchi; Cromolyn Sodi | 1990 |
[Asthmatic illness: basic trial treatment by ketotifen (apropos of 48 cases)].
Topics: Adolescent; Adult; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male; Middle Aged | 1990 |
Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma.
Topics: Adolescent; Allergens; Asthma; Child; Child, Preschool; Concanavalin A; Dermatitis, Atopic; Female; | 1990 |
Sociodemographic and motivational characteristics of parents who volunteer their children for clinical research: a controlled study.
Topics: Adult; Asthma; Attitude to Health; Child, Preschool; Decision Making; Double-Blind Method; Emotions; | 1990 |
[Progress of therapeutic agents for asthma--2. Prophylactic anti-asthmatic agents].
Topics: Administration, Inhalation; Administration, Oral; Animals; Asthma; Child, Preschool; Cromolyn Sodium | 1987 |
[Prognosis presumption with bronchial asthma at the first medical examination--II--Selection of a therapeutic method by multiple factor analysis].
Topics: Asthma; Child; Child, Preschool; Desensitization, Immunologic; Factor Analysis, Statistical; Female; | 1988 |
[Therapeutic aspects of intractable asthma].
Topics: Adult; Aged; Asthma; Cromolyn Sodium; Female; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzo | 1988 |
[Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents].
Topics: Adult; Asthma; Bronchi; Cromolyn Sodium; Drug Therapy, Combination; Female; Histamine; Humans; Ketot | 1989 |
[The investigation of asthmatic children by multiple factor analysis. III. The changes in allergic factors selected by multiple factor analysis in 3 anti-allergic during treated groups over one year].
Topics: Adolescent; Asthma; Child; Child, Preschool; Eosinophils; Female; Histamine H1 Antagonists; Humans; | 1989 |
Late asthmatic response to allergen challenge (LAR), its clinical feature and pharmacological modulation.
Topics: Albuterol; Allergens; Asthma; Beclomethasone; Bronchial Provocation Tests; Cromolyn Sodium; Humans; | 1989 |
[IgE-Fc receptor expressions on bronchoalveolar lavage (BAL) cells in a patient with eosinophilic pneumonia accompanied with bronchial asthma--the effect of ketotifen on their expression].
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Eo | 1989 |
[The possible effect of a ketotifen preparation on beta-receptor blockade].
Topics: Adrenergic beta-Antagonists; Adult; Animals; Asthma; Bronchi; Bronchodilator Agents; Drug Evaluation | 1989 |
Exercise-induced allergic syndromes on the increase.
Topics: Adolescent; Adult; Albuterol; Anaphylaxis; Asthma; Asthma, Exercise-Induced; Beclomethasone; Exercis | 1989 |
[Ketotifen treatment of bronchial asthma].
Topics: Adolescent; Adult; Asthma; Drug Evaluation; Drug Therapy, Combination; Female; Glucocorticoids; Huma | 1989 |
Steroid-sparing effect of ketotifen in steroid-dependent asthmatics: a long period evaluation in 12 patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Asthma; Bronchodilator Agents; Female; Humans; Hydrocortis | 1988 |
Effect of PAF-acether in non-human primates.
Topics: Airway Resistance; Animals; Asthma; Bronchial Spasm; Constriction, Pathologic; Cromolyn Sodium; Keto | 1988 |
Effects of ketotifen on the responsiveness of peripheral blood lymphocyte beta-adrenergic receptors.
Topics: Adolescent; Adult; Aged; Asthma; Cyclic AMP; Dihydroalprenolol; Female; Humans; In Vitro Techniques; | 1988 |
[Preventive drug therapy in allergic bronchial asthma].
Topics: Asthma; Cromolyn Sodium; Histamine H1 Antagonists; Humans; Ketotifen; Piperazines; Respiratory Hyper | 1986 |
Antiasthmatic drugs--opening remarks.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Cromolyn Sodium; Humans; Ketotifen; Paras | 1986 |
[Potentiation of the bronchodilating effect of beta-adrenergic agonists in guinea pigs with ketotifen].
Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchi; Drug Synergism; Female; Guinea Pigs; In Vitro Te | 1986 |
A comparison of the PD35-sGaw and PD20-FEV1 in assessment of the effect of oral anti-allergic compounds on the immediate asthmatic response to inhaled allergen.
Topics: Adult; Airway Resistance; Allergens; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; For | 1987 |
Ketotifen prevents terbutaline-induced down-regulation of beta-adrenoceptors in guinea pig lung.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Dose-Response Relationship, Drug; Drug Interactions; Guin | 1988 |
Effect of prednisolone and ketotifen on beta 2-adrenoceptors in asthmatic patients receiving beta 2-bronchodilators.
Topics: Adrenergic beta-Antagonists; Adult; Albuterol; Asthma; Bronchodilator Agents; Cyclic AMP; Female; Hu | 1988 |
Cellular immunity and suppressor T cell function in asthmatic children on prolonged ketotifen therapy.
Topics: Adolescent; Asthma; Child; Child, Preschool; Concanavalin A; Female; Humans; Immunity, Cellular; Ket | 1988 |
Effect of adding ketotifen to ipratropium bromide in the treatment of nocturnal asthma.
Topics: Adult; Asthma; Atropine Derivatives; Drug Therapy, Combination; Female; Humans; Ipratropium; Ketotif | 1988 |
[Comparison of the effects of Kenalog and Zaditen on the clinical state and plasma cAMP levels of patients with bronchial asthma].
Topics: Asthma; Cyclic AMP; Humans; Ketotifen; Triamcinolone Acetonide | 1985 |
Effects of ketotifen upon responses to platelet activating factor: a basis for asthma prophylaxis.
Topics: Albuterol; Asthma; Cromolyn Sodium; Humans; Hypersensitivity; Injections, Intravenous; Ketotifen; Lu | 1986 |
Drug treatment in bronchial asthma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Bronchodilator Agents; Child; Child, Preschool; | 1986 |
Prophylactic treatment of childhood asthma.
Topics: Adult; Asthma; Breast Feeding; Child; Cromolyn Sodium; Desensitization, Immunologic; Female; Food Hy | 1986 |
Childhood asthma, response to oral prophylaxis.
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male; Prospective Studies | 1986 |
[Therapy of allergic rhinitis in childhood].
Topics: Asthma; Beclomethasone; Child; Cromolyn Sodium; Desensitization, Immunologic; Humans; Ketotifen; Rhi | 1987 |
Protective effect of ketotifen on chemiluminescence of neutrophils.
Topics: Asthma; Humans; Ketotifen; Kinetics; Luminescent Measurements; Neutrophils; Oxidation-Reduction | 1988 |
Pharmacology of ketotifen in asthma.
Topics: Asthma; Humans; Ketotifen | 1986 |
Platelet activating factor, ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1986 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1986 |
Asthma therapy in children.
Topics: Aminophylline; Asthma; Child; Child Behavior; Drug Interactions; Humans; Ketotifen | 1986 |
PAF, ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1987 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen | 1986 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen | 1987 |
Re: Aplastic anaemia & ketotifen.
Topics: Anemia, Aplastic; Asthma; Child, Preschool; Female; Humans; Ketotifen | 1986 |
[Therapeutic and preventive effect of ketotifen in bronchial asthma].
Topics: Adolescent; Adult; Asthma; Female; Humans; Ketotifen; Male; Respiratory Function Tests | 1987 |
[Clinical results of the treatment with ketotifen in asthmatic children in Zaire. Apropos of 36 cases followed at university clinics in Kinshasa (Zaire)].
Topics: Administration, Oral; Asthma; Child; Child, Preschool; Democratic Republic of the Congo; Female; Hum | 1987 |
[Treatment of an asthmatic syndrome of infants with ketotifen. Comparison of the effectiveness of ketotifen and others treatments].
Topics: Asthma; Child, Preschool; Drug Evaluation; Female; Humans; Immunoglobulin E; Infant; Ketotifen; Male | 1986 |
Ketotifen in the management of asthmatic children in private practice.
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Ketotifen; Male | 1986 |
The prophylactic benefits of twice-daily ketotifen in asthmatic Saudi children.
Topics: Asthma; Asthma, Exercise-Induced; Child; Drug Administration Schedule; Female; Humans; Ketotifen; Ma | 1986 |
The determination of pharmacokinetic parameters of ketotifen in steady state in young children.
Topics: Asthma; Biological Availability; Child, Preschool; Dermatitis, Atopic; Female; Humans; Ketotifen; Ki | 1986 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen | 1985 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen | 1985 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen | 1985 |
Ketotifen and asthma.
Topics: Asthma; Family Practice; Humans; Ketotifen | 1985 |
Underutilisation of prophylactic drugs in asthmatic children.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Asthma; Child; Child, Preschool; Cromolyn | 1985 |
[Treatment of chronic bronchial asthma].
Topics: Asthma; Chronic Disease; Cromolyn Sodium; Glucocorticoids; Humans; Ketotifen; Male; Nifedipine; Para | 1985 |
Ketotifen action upon the immunity state in bronchial asthma.
Topics: Adolescent; Adult; Antibodies; Asthma; Humans; Immunity, Cellular; Immunoglobulins; Ketotifen | 1985 |
[Comparative study of the effect of intal and zaditen in patients with atopic bronchial asthma at Sandanski health resort].
Topics: Adolescent; Adult; Asthma; Bulgaria; Cromolyn Sodium; Drug Evaluation; Female; Health Resorts; Human | 1985 |
Prevention of bronchial hyperreactivity in atopic asthmatics during the period of maximal allergenic risk: a six-month study.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Forced Expiratory Volume; Humans; Hyp | 1986 |
[Ketotifen in the prevention of bronchial asthma of allergic origin in children].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Hypersensitivity; Ketotifen; Male | 1986 |
[Development of clinical symptoms in asthmatic children under long-term treatment of ketotifen].
Topics: Adolescent; Asthma; Child; Child, Preschool; Double-Blind Method; Female; Humans; Ketotifen; Male; R | 1985 |
[Effect of Zaditen on plasma immunoglobulin levels in patients with bronchial asthma].
Topics: Adolescent; Adult; Asthma; Desensitization, Immunologic; Humans; Immunoglobulins; Immunosuppressive | 1985 |
Immunologic and therapeutic aspects of ketotifen.
Topics: Anaphylaxis; Animals; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Heart Rate; Humans; Isop | 1985 |
[Effect of Zaditen on the clinical status and ventilatory parameters in patients with various types of bronchial asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Humans; Ketotifen; Middl | 1985 |
Inhaled ketotifen in exercise-induced asthma--a negative report.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Humans; Ketot | 1985 |