ketotifen has been researched along with Arthropathies in 2 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of a mast cell stabilizer, ketotifen, was effective in reducing the biomechanical and cellular manifestations of joint capsule fibrosis in a rabbit model of posttraumatic joint contracture." | 7.76 | The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures. ( Befus, AD; Hart, DA; Hildebrand, KA; Monument, MJ; Salo, PT; Zhang, M, 2010) |
| " The purpose of this study was to use a validated rabbit model to assess the effects on surgically-induced knee joint contractures of two combined pharmacological interventions: celecoxib (CXB) loaded on an implanted collagen membrane, and subcutaneously (SQ) injected ketotifen." | 3.96 | Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen. ( Abdel, MP; Berry, CE; Berry, DJ; Bolon, B; Carter, JM; Jay, AG; Limberg, AK; McLaury, AR; Morrey, ME; Salib, CG; Sanchez-Sotelo, J; Tibbo, ME; Turner, TW; van Wijnen, AJ, 2020) |
| "The use of a mast cell stabilizer, ketotifen, was effective in reducing the biomechanical and cellular manifestations of joint capsule fibrosis in a rabbit model of posttraumatic joint contracture." | 3.76 | The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures. ( Befus, AD; Hart, DA; Hildebrand, KA; Monument, MJ; Salo, PT; Zhang, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Limberg, AK | 1 |
| Tibbo, ME | 1 |
| Salib, CG | 1 |
| McLaury, AR | 1 |
| Turner, TW | 1 |
| Berry, CE | 1 |
| Jay, AG | 1 |
| Carter, JM | 1 |
| Bolon, B | 1 |
| Berry, DJ | 1 |
| Morrey, ME | 1 |
| Sanchez-Sotelo, J | 1 |
| van Wijnen, AJ | 1 |
| Abdel, MP | 1 |
| Monument, MJ | 1 |
| Hart, DA | 1 |
| Befus, AD | 1 |
| Salo, PT | 1 |
| Zhang, M | 1 |
| Hildebrand, KA | 1 |
2 other studies available for ketotifen and Arthropathies
| Article | Year |
|---|---|
Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen.
Topics: Animals; Celecoxib; Contracture; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Delivery | 2020 |
The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures.
Topics: Animals; Anti-Inflammatory Agents; Contracture; Disease Models, Animal; Fibroblasts; Hyperplasia; Im | 2010 |