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ketotifen and Acquired Immunodeficiency Syndrome

ketotifen has been researched along with Acquired Immunodeficiency Syndrome in 4 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"The effect of the testosterone derivative oxymetholone alone or in combination with the H1-receptor antagonist ketotifen, which has recently been shown to block tumour necrosis factor alpha (TNF alpha), on weight gain and performance status in human immunodeficiency virus (HIV) patients with chronic cachexia was evaluated in a 30-week prospective pilot study."9.08Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection. ( Baumann, M; Brockmeyer, NH; Goos, M; Hengge, UR; Maleba, R, 1996)
"The effect of the testosterone derivative oxymetholone alone or in combination with the H1-receptor antagonist ketotifen, which has recently been shown to block tumour necrosis factor alpha (TNF alpha), on weight gain and performance status in human immunodeficiency virus (HIV) patients with chronic cachexia was evaluated in a 30-week prospective pilot study."5.08Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection. ( Baumann, M; Brockmeyer, NH; Goos, M; Hengge, UR; Maleba, R, 1996)
"Thalidomide may cause birth defects, and larger doses can cause neuropathy or other adverse effects."1.29Wasting syndrome--affordable treatments. ( James, JS, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hengge, UR1
Baumann, M1
Maleba, R1
Brockmeyer, NH1
Goos, M1
Smart, T1
Grunfeld, C1
James, JS1

Trials

1 trial available for ketotifen and Acquired Immunodeficiency Syndrome

ArticleYear
Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection.
    The British journal of nutrition, 1996, Volume: 75, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anabolic Agents; Body Mass Index; Cachexia; Drug Therapy,

1996

Other Studies

3 other studies available for ketotifen and Acquired Immunodeficiency Syndrome

ArticleYear
Other therapies for wasting.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anabolic Agents; Cannabidiol; Dronabinol; Female; Humans; Ketoti

1995
State of the art in wasting: an interview with Carl Grunfeld, PhD. Interview by Jeff Getty.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Animals; Cachexia; Endocr

1995
Wasting syndrome--affordable treatments.
    AIDS treatment news, 1995, Jul-07, Issue:no 226

    Topics: Acquired Immunodeficiency Syndrome; Cachexia; Costs and Cost Analysis; Dronabinol; Exercise Therapy;

1995