ketotifen has been researched along with Absence Seizure in 6 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical reports have shown that some antihistamines, such as ketotifen, occasionally produced seizures, especially in pre-school age children or young patients with epilepsy." | 7.78 | The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats. ( Kanda, T; Takizawa, F; Tamura, T; Yamada, K, 2012) |
| "Clinical reports have shown that some antihistamines, such as ketotifen, occasionally produced seizures, especially in pre-school age children or young patients with epilepsy." | 3.78 | The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats. ( Kanda, T; Takizawa, F; Tamura, T; Yamada, K, 2012) |
| " The centrally acting histamine H1 antagonists including pyrilamine (mepyramine) and ketotifen showed an acceleration in the rate of electrical stimulation to develop fully kindled convulsive seizures." | 3.69 | Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats. ( Iinuma, K; Onodera, K; Sato, M; Watanabe, T; Yokoyama, H, 1996) |
| "Ketotifen produced seizures in a 5-year-old boy with secondary generalized epilepsy (SGE) and allergic rhinitis." | 3.68 | Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography. ( Iinuma, K; Onodera, K; Sakurai, E; Watanabe, T; Yanai, K; Yokoyama, H, 1993) |
| "In this study, electroconvulsion was induced by stimulating rats using ear-clip electrodes, and the durations of electroencephalogram (EEG) seizure, tonic extensor (TE) seizure and clonic (CL) seizure induced by maximal electroshock were measured." | 1.34 | Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. ( Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, K | 1 |
| Takizawa, F | 1 |
| Tamura, T | 1 |
| Kanda, T | 1 |
| Swiader, M | 1 |
| Wielosz, M | 1 |
| Czuczwar, SJ | 1 |
| Ishikawa, T | 1 |
| Takechi, K | 1 |
| Rahman, A | 1 |
| Ago, J | 1 |
| Matsumoto, N | 1 |
| Murakami, A | 1 |
| Kamei, C | 1 |
| Yokoyama, H | 2 |
| Iinuma, K | 2 |
| Yanai, K | 1 |
| Watanabe, T | 2 |
| Sakurai, E | 1 |
| Onodera, K | 2 |
| Sato, M | 1 |
| Yamanaka, K | 1 |
| Kuwashima, K | 1 |
6 other studies available for ketotifen and Absence Seizure
| Article | Year |
|---|---|
The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.
Topics: Age Factors; Animals; Anti-Allergic Agents; Brain; Caffeine; Central Nervous System Stimulants; Dibe | 2012 |
Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice.
Topics: Animals; Antazoline; Anticonvulsants; Avoidance Learning; Behavior, Animal; Brain; Brain Chemistry; | 2004 |
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; | 2007 |
Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography.
Topics: Child, Preschool; Chlorpheniramine; Dopamine; Electroencephalography; Epilepsies, Partial; Epinephri | 1993 |
Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats.
Topics: Amygdala; Animals; Dibenzazepines; Electroencephalography; Histamine H1 Antagonists; Imidazoles; Ket | 1996 |
[Effect of ketotifen fumarate for seizures in Lennox-Gastaut syndrome; a care report].
Topics: Administration, Oral; Anti-Allergic Agents; Child; Dermatitis, Atopic; Epilepsy, Absence; Humans; Ke | 1999 |