Page last updated: 2024-10-29

ketorolac and Tongue Neoplasms

ketorolac has been researched along with Tongue Neoplasms in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Tongue Neoplasms: Tumors or cancer of the TONGUE.

Research Excerpts

ExcerptRelevanceReference
"Ketorolac salt was selected based on its binding free energy less than or equals to -5 Kcal/mol with reference to existing synthetic DDX3 inhibitors and strong hydrogen bond interactions as similar to crystallized DDX3 protein (2I4I)."1.42Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer. ( Botlagunta, M; Dash, R; Routray, S; Samal, SK; Veeramachaneni, GK, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Samal, SK1
Routray, S1
Veeramachaneni, GK1
Dash, R1
Botlagunta, M1
McCann, KJ1
Irish, J1

Other Studies

2 other studies available for ketorolac and Tongue Neoplasms

ArticleYear
Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer.
    Scientific reports, 2015, Apr-28, Volume: 5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DEAD-box

2015
Postoperative gastrointestinal bleeding: a case report involving a non-steroidal anti-inflammatory drug.
    Journal (Canadian Dental Association), 1994, Volume: 60, Issue:2

    Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Female; Histami

1994