ketorolac has been researched along with Thrombosis in 3 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketorolac administration has a protective effect against the development of microvascular thrombosis and can be a preferred analgesic in free tissue transfer." | 7.78 | The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction. ( Bang, SI; Jeon, BJ; Lee, KT; Lim, SY; Mun, GH; Oh, KS; Pyon, JK, 2012) |
| "Ketorolac administration has a protective effect against the development of microvascular thrombosis and can be a preferred analgesic in free tissue transfer." | 3.78 | The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction. ( Bang, SI; Jeon, BJ; Lee, KT; Lim, SY; Mun, GH; Oh, KS; Pyon, JK, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JS | 1 |
| Kaufman, J | 1 |
| Patel, SS | 1 |
| Manco-Johnson, M | 1 |
| Di Paola, J | 1 |
| da Cruz, EM | 1 |
| Lee, KT | 1 |
| Jeon, BJ | 1 |
| Lim, SY | 1 |
| Pyon, JK | 1 |
| Bang, SI | 1 |
| Oh, KS | 1 |
| Mun, GH | 1 |
| Longo, B | 1 |
| Santanelli, F | 1 |
3 other studies available for ketorolac and Thrombosis
| Article | Year |
|---|---|
Antiplatelet Effect of Ketorolac in Children After Congenital Cardiac Surgery.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Child; Child, Pres | 2018 |
The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cyclooxygenase Inhibitors; Female; Follow-Up Stud | 2012 |
The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction.
Topics: Female; Free Tissue Flaps; Humans; Ketorolac; Lower Extremity; Male; Microcirculation; Plastic Surge | 2012 |