Page last updated: 2024-10-29

ketorolac and Thrombosis

ketorolac has been researched along with Thrombosis in 3 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
"Ketorolac administration has a protective effect against the development of microvascular thrombosis and can be a preferred analgesic in free tissue transfer."7.78The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction. ( Bang, SI; Jeon, BJ; Lee, KT; Lim, SY; Mun, GH; Oh, KS; Pyon, JK, 2012)
"Ketorolac administration has a protective effect against the development of microvascular thrombosis and can be a preferred analgesic in free tissue transfer."3.78The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction. ( Bang, SI; Jeon, BJ; Lee, KT; Lim, SY; Mun, GH; Oh, KS; Pyon, JK, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, JS1
Kaufman, J1
Patel, SS1
Manco-Johnson, M1
Di Paola, J1
da Cruz, EM1
Lee, KT1
Jeon, BJ1
Lim, SY1
Pyon, JK1
Bang, SI1
Oh, KS1
Mun, GH1
Longo, B1
Santanelli, F1

Other Studies

3 other studies available for ketorolac and Thrombosis

ArticleYear
Antiplatelet Effect of Ketorolac in Children After Congenital Cardiac Surgery.
    World journal for pediatric & congenital heart surgery, 2018, Volume: 9, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Child; Child, Pres

2018
The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction.
    Plastic and reconstructive surgery, 2012, Volume: 129, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cyclooxygenase Inhibitors; Female; Follow-Up Stud

2012
The effects of ketorolac on microvascular thrombosis in lower extremity reconstruction.
    Plastic and reconstructive surgery, 2012, Volume: 130, Issue:4

    Topics: Female; Free Tissue Flaps; Humans; Ketorolac; Lower Extremity; Male; Microcirculation; Plastic Surge

2012