Page last updated: 2024-10-29

ketorolac and Syndrome

ketorolac has been researched along with Syndrome in 5 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
" Ketorolac can be well tolerated in high-dose, long-term use even in this frail patient population."6.69The opioid-sparing effects of intravenous ketorolac as an adjuvant analgesic in cancer pain: application in bone metastases and the opioid bowel syndrome. ( Joishy, SK; Walsh, D, 1998)
" Ketorolac can be well tolerated in high-dose, long-term use even in this frail patient population."2.69The opioid-sparing effects of intravenous ketorolac as an adjuvant analgesic in cancer pain: application in bone metastases and the opioid bowel syndrome. ( Joishy, SK; Walsh, D, 1998)
"The presence of lymphedema is likely the predisposing factor for development of recurrent infections in such patients."1.35Recurrent cellulitis in a case of Aagenaes syndrome. ( Dang, S; Davies, D; Sigal, Y, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sosa, PS1
Colla-Machado, PE1
Cristiano, E1
Dang, S1
Sigal, Y1
Davies, D1
Marangi, GF1
Gigliofiorito, P1
Toto, V1
Langella, M1
Pallara, T1
Persichetti, P1
Iacobucci, T1
Nanni, L1
Picoco, F1
de Francisci, G1
Joishy, SK1
Walsh, D1

Trials

1 trial available for ketorolac and Syndrome

ArticleYear
The opioid-sparing effects of intravenous ketorolac as an adjuvant analgesic in cancer pain: application in bone metastases and the opioid bowel syndrome.
    Journal of pain and symptom management, 1998, Volume: 16, Issue:5

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Colonic Ps

1998

Other Studies

4 other studies available for ketorolac and Syndrome

ArticleYear
[Pisa syndrome associated with codeine].
    Revista de neurologia, 2018, 07-15, Volume: 67, Issue:2

    Topics: Acetaminophen; Aged; Analgesics; Back Pain; Breast Neoplasms; Carcinoma, Lobular; Codeine; Drug Subs

2018
Recurrent cellulitis in a case of Aagenaes syndrome.
    Clinical pediatrics, 2009, Volume: 48, Issue:8

    Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cellulitis;

2009
Three cases of embolia cutis medicamentosa (Nicolau's syndrome).
    The Journal of dermatology, 2010, Volume: 37, Issue:5

    Topics: Aged; Diclofenac; Fat Necrosis; Female; Humans; Injections, Intramuscular; Ketorolac; Middle Aged; N

2010
Anesthesia for a child with Wolf-Hirshhorn syndrome.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:11

    Topics: Abnormalities, Multiple; Alfentanil; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2004