ketorolac has been researched along with Strabismus in 9 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the efficacy of preoperative intravenous ketorolac in reducing intraoperative and postoperative pain and improving patient satisfaction in patients undergoing single-stage adjustable strabismus surgery." | 9.15 | The efficacy of intravenous ketorolac for pain relief in single-stage adjustable strabismus surgery: a prospective, randomized, placebo-controlled trial. ( Bae, SJ; Chang, JH; Chung, SA; Kim, WK; Lee, JB; Rhiu, S, 2011) |
| "5% ketorolac eye drops at the start and end of strabismus repair surgery." | 9.10 | Amethocaine or ketorolac eyedrops provide inadequate analgesia in pediatric strabismus surgery. ( Azavedo, L; Bhananker, S; Bonn, G; Kim, J; Splinter, W, 2003) |
| "To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children." | 9.09 | Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 9.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 9.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 9.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "To determine the efficacy of preoperative intravenous ketorolac in reducing intraoperative and postoperative pain and improving patient satisfaction in patients undergoing single-stage adjustable strabismus surgery." | 5.15 | The efficacy of intravenous ketorolac for pain relief in single-stage adjustable strabismus surgery: a prospective, randomized, placebo-controlled trial. ( Bae, SJ; Chang, JH; Chung, SA; Kim, WK; Lee, JB; Rhiu, S, 2011) |
| "5% ketorolac eye drops at the start and end of strabismus repair surgery." | 5.10 | Amethocaine or ketorolac eyedrops provide inadequate analgesia in pediatric strabismus surgery. ( Azavedo, L; Bhananker, S; Bonn, G; Kim, J; Splinter, W, 2003) |
| "To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children." | 5.09 | Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 5.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 5.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 5.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "Postoperative pain is a significant cause of morbidity in pediatric anesthesia, which can result in delayed discharge and unplanned hospital admission." | 1.56 | Reducing postoperative pain in children undergoing strabismus surgery: From bundle implementation to clinical decision support tools. ( Ali, U; Balakrishnan, S; Campbell, F; Igbeyi, B; Kotzer, G; Matava, C; Mc Donnell, C; Shackell, K; Tsang, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, U | 1 |
| Tsang, M | 1 |
| Campbell, F | 1 |
| Matava, C | 1 |
| Igbeyi, B | 1 |
| Balakrishnan, S | 1 |
| Shackell, K | 1 |
| Kotzer, G | 1 |
| Mc Donnell, C | 1 |
| Rhiu, S | 1 |
| Chung, SA | 1 |
| Kim, WK | 1 |
| Chang, JH | 1 |
| Bae, SJ | 1 |
| Lee, JB | 1 |
| Kim, J | 1 |
| Azavedo, L | 1 |
| Bhananker, S | 1 |
| Bonn, G | 1 |
| Splinter, W | 1 |
| Mendel, HG | 1 |
| Guarnieri, KM | 1 |
| Sundt, LM | 1 |
| Torjman, MC | 1 |
| Munro, HM | 3 |
| Riegger, LQ | 2 |
| Reynolds, PI | 2 |
| Wilton, NC | 1 |
| Lewis, IH | 1 |
| Morrison, NA | 1 |
| Repka, MX | 1 |
| D'Errico, CC | 1 |
| Lauder, GR | 1 |
| Wagner, DS | 1 |
| Voepel-Lewis, T | 1 |
| Tait, AR | 1 |
| Bridge, HS | 1 |
| Montgomery, CJ | 1 |
| Kennedy, RA | 1 |
| Merrick, PM | 1 |
7 trials available for ketorolac and Strabismus
| Article | Year |
|---|---|
The efficacy of intravenous ketorolac for pain relief in single-stage adjustable strabismus surgery: a prospective, randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Analgesia; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cycloox | 2011 |
Amethocaine or ketorolac eyedrops provide inadequate analgesia in pediatric strabismus surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Presch | 2003 |
The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia; Child; Child, P | 1995 |
Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Method; Female; Hu | 1994 |
Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory A | 1994 |
Oral granisetron for strabismus surgery in children.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Antiemetics; | 1999 |
Analgesic efficacy of ketorolac 0.5% ophthalmic solution (Accular) in paediatric strabismus surgery.
Topics: Child; Child, Preschool; Double-Blind Method; Female; Humans; Ketorolac; Male; Ophthalmic Solutions; | 2000 |
2 other studies available for ketorolac and Strabismus
| Article | Year |
|---|---|
Reducing postoperative pain in children undergoing strabismus surgery: From bundle implementation to clinical decision support tools.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child | 2020 |
Ketorolac and strabismus surgery.
Topics: Analgesics, Non-Narcotic; Humans; Ketorolac; Postoperative Complications; Strabismus; Tolmetin; Vomi | 1996 |