ketorolac has been researched along with Spasm in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the efficacy of ketorolac in suppressing postoperative bladder spasms after ureteroneocystostomy (ureteral reimplantation)." | 9.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| "We evaluated the efficacy of ketorolac in suppressing postoperative bladder spasms after ureteroneocystostomy (ureteral reimplantation)." | 5.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "Ketorolac was more effective in reducing the frequency of bladder spasms and rescue analgesic requirements." | 2.76 | Ketorolac or fentanyl continuous infusion for post-operative analgesia in children undergoing ureteroneocystostomy. ( Choi, EK; Hong, JY; Jo, YY; Kil, HK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Young, KM | 1 |
| Jo, YY | 1 |
| Hong, JY | 1 |
| Choi, EK | 1 |
| Kil, HK | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Park, JM | 1 |
| Houck, CS | 1 |
| Sethna, NF | 1 |
| Sullivan, LJ | 1 |
| Atala, A | 1 |
| Borer, JG | 1 |
| Cilento, BG | 1 |
| Diamond, DA | 1 |
| Peters, CA | 1 |
| Retik, AB | 1 |
| Bauer, SB | 1 |
2 trials available for ketorolac and Spasm
| Article | Year |
|---|---|
Ketorolac or fentanyl continuous infusion for post-operative analgesia in children undergoing ureteroneocystostomy.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Cystostomy; Double-Bl | 2011 |
Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cystostomy; Double-Blind Method; H | 2000 |
2 other studies available for ketorolac and Spasm
| Article | Year |
|---|---|
Simple rules, complex behavior.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Constipation; Diagnosis, D | 2008 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |