Page last updated: 2024-10-29

ketorolac and Respiratory Tract Diseases

ketorolac has been researched along with Respiratory Tract Diseases in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Respiratory Tract Diseases: Diseases involving the RESPIRATORY SYSTEM.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Celikel, S1
Stevenson, D2
Erkorkmaz, U1
White, AA1
White, A1
Bigby, T1

Trials

2 trials available for ketorolac and Respiratory Tract Diseases

ArticleYear
Use of nasal inspiratory flow rates in the measurement of aspirin-induced respiratory reactions.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 111, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Inhalation; Ketorolac; Male

2013
Intranasal ketorolac challenge for the diagnosis of aspirin-exacerbated respiratory disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2

    Topics: Administration, Intranasal; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Dr

2006