ketorolac has been researched along with Reperfusion Injury in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Franceschi, L | 1 |
| Mura, P | 1 |
| Schweiger, V | 1 |
| Vencato, E | 1 |
| Quaglia, FM | 1 |
| Delmonte, L | 1 |
| Evangelista, M | 1 |
| Polati, E | 1 |
| Olivieri, O | 1 |
| Finco, G | 1 |
| Hsieh, YC | 1 |
| Cheng, H | 1 |
| Chan, KH | 1 |
| Chang, WK | 1 |
| Liu, TM | 1 |
| Wong, CS | 1 |
2 other studies available for ketorolac and Reperfusion Injury
| Article | Year |
|---|---|
Fentanyl Buccal Tablet: A New Breakthrough Pain Medication in Early Management of Severe Vaso-Occlusive Crisis in Sickle Cell Disease.
Topics: Administration, Buccal; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Anti-Inflammator | 2016 |
Protective effect of intrathecal ketorolac in spinal cord ischemia in rats: a microdialysis study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Chromatography, High Pressure Liquid; | 2007 |