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ketorolac and Reflex Sympathetic Dystrophy

ketorolac has been researched along with Reflex Sympathetic Dystrophy in 3 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suresh, S1
Wheeler, M1
Patel, A1
Farah, BA1
Vanos, DN1
Ramamurthy, S1
Hoffman, J1

Other Studies

3 other studies available for ketorolac and Reflex Sympathetic Dystrophy

ArticleYear
Case series: IV regional anesthesia with ketorolac and lidocaine: is it effective for the management of complex regional pain syndrome 1 in children and adolescents?
    Anesthesia and analgesia, 2003, Volume: 96, Issue:3

    Topics: Adolescent; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Anti-Inflammatory A

2003
Ketorolac in reflex sympathetic dystrophy.
    Clinical neuropharmacology, 1993, Volume: 16, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Male; Reflex Sympathetic Dystroph

1993
Intravenous regional block using ketorolac: preliminary results in the treatment of reflex sympathetic dystrophy.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Injections, Intravenous; Ketorolac;

1992