ketorolac has been researched along with Pulmonary Embolism in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Present studies examine effects of the nonsteroidal anti-inflammatory drug, ketorolac, upon RV inflammation and dysfunction." | 7.75 | Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats. ( Gellar, MA; Kline, JA; Obraztsova, M; Stuart, LK; Watts, JA, 2009) |
| " Present studies examine effects of the nonsteroidal anti-inflammatory drug, ketorolac, upon RV inflammation and dysfunction." | 3.75 | Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats. ( Gellar, MA; Kline, JA; Obraztsova, M; Stuart, LK; Watts, JA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, A | 1 |
| Watts, JA | 2 |
| Gellar, MA | 1 |
| Stuart, LK | 1 |
| Obraztsova, M | 1 |
| Kline, JA | 2 |
| Jones, AE | 1 |
| Debelak, JP | 1 |
| Thornton, LR | 1 |
| Younger, JG | 1 |
| Petrusewicz, J | 1 |
| Turowski, M | 1 |
| Foks, H | 1 |
| Pilarski, B | 1 |
| Kaliszan, R | 1 |
4 other studies available for ketorolac and Pulmonary Embolism
| Article | Year |
|---|---|
A 61-Year-Old Man with Flank Pain.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Diagnosis, Differential | 2016 |
Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Cyclooxygenase 2; Cyclooxygenase | 2009 |
Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat.
Topics: Angiography; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenas | 2003 |
Comparative studies of antiplatelet activity of nonsteroidal antiinflammatory drugs and new pyrazine CH- and NH-acids.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Epinephrine; Fibr | 1995 |