ketorolac has been researched along with Prostatic Hyperplasia in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Men treated with tamsulosin having standard cataract extraction surgery were placed in a treatment group that received phenylephrine 1." | 2.87 | Effect of phenylephrine 1.0%-ketorolac 0.3% injection on tamsulosin-associated intraoperative floppy-iris syndrome. ( Juzych, MS; Nariman, N; Pankratz, J; Rana, S; Rana, VK; Segars, L; Silverstein, SM; Stephens, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silverstein, SM | 1 |
| Rana, VK | 1 |
| Stephens, R | 1 |
| Segars, L | 1 |
| Pankratz, J | 1 |
| Rana, S | 1 |
| Juzych, MS | 1 |
| Nariman, N | 1 |
| Tomera, KM | 1 |
| Scheuren, JP | 1 |
| York, W | 1 |
2 trials available for ketorolac and Prostatic Hyperplasia
| Article | Year |
|---|---|
Effect of phenylephrine 1.0%-ketorolac 0.3% injection on tamsulosin-associated intraoperative floppy-iris syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and ov | 2018 |
Transurethral microwave thermotherapy: strategies to ensure successful outcomes with Prostasoft 2.0.
Topics: Aged; Analgesics, Non-Narcotic; Follow-Up Studies; Humans; Hyperthermia, Induced; Injections, Intram | 1997 |