ketorolac has been researched along with Postoperative Complications in 90 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Participants scheduled for cataract removal were randomized to 1 of 5 anti-inflammatory prophylactic regimens: eye drops with a combination of prednisolone, 1%, and ketorolac tromethamine, 0." | 9.41 | Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial. ( Erichsen, JH; Forman, JL; Forslund Jacobsen, M; Holm, LM; Kessel, L, 2021) |
| " We sought to determine if the use of intraoperative ketorolac as part of a multimodal ERAS protocol increased the risk of bleeding complications in breast surgery." | 9.30 | Intraoperative Ketorolac Use Does Not Increase the Risk of Bleeding in Breast Surgery. ( Andaz, C; Borgen, P; Flom, P; Fortes, TA; Manasseh, DM; Rojas, KE, 2019) |
| "A total 91 subjects scheduled to undergo cataract operation were randomized into three groups: Group 1, pre/postoperative bromfenac 0." | 9.20 | The Effects of Two Non-Steroidal Anti-Inflammatory Drugs, Bromfenac 0.1% and Ketorolac 0.45%, on Cataract Surgery. ( Chung, BH; Jung, JW; Kim, EK; Kim, TI; Seo, KY, 2015) |
| "We studied the efficacy of ketorolac, a prostaglandin synthesis inhibitor, in the treatment of bladder spasm after ureteroneocystostomy (antireflux operation)." | 9.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| "This double-blind randomized trial assessed the effect of adding an intravenous continuous infusion of ketorolac to a patient-controlled analgesia (PCA) morphine regimen on analgesia, heart rate, arterial blood pressure, and postoperative myocardial ischemia." | 9.08 | The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty. ( Badner, NH; Beattie, WS; Buckley, N; Chan, V; Etches, R; Girard, M; Parsons, D; Warriner, CB, 1997) |
| "To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning." | 9.08 | Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 9.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 9.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 9.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "As a new ophthalmic non-steroidal anti-inflammatory drug (NSAID) with prodrug structure, Nepafenac was supposed to have a better efficacy than conventional NSAIDs both in patients' tolerability and ocular inflammation associated with cataract surgery." | 8.95 | Comparison of the efficacy and patients' tolerability of Nepafenac and Ketorolac in the treatment of ocular inflammation following cataract surgery: A meta-analysis of randomized controlled trials. ( Chen, Y; Wang, E; Xia, S; Zhao, X, 2017) |
| "To assess the effectiveness of ketorolac vs control for prevention of acute pseudophakic cystoid macular edema (CME)." | 8.88 | Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review. ( Cordero-Coma, M; Gallagher, MJ; Yilmaz, T, 2012) |
| "This study demonstrated 40% mortality reduction with intravenous ketorolac following open abdominal aortic aneurysm repair." | 8.02 | Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair. ( Al-Nouri, O; Locham, S; Malas, MB; Naazie, IN; Nejim, B; Weaver, ML, 2021) |
| " There is conflicting evidence that ketorolac use in inflammatory bowel disease (IBD) may precipitate disease flares and postoperative complications." | 7.96 | Ketorolac after colectomy for ulcerative colitis in children: An analysis of opioid utilization and postoperative complications. ( Deneau, M; Guthery, SL; Short, SS; Taylor, MA; West, WB, 2020) |
| "To assess the effectiveness of intracameral phenylephrine-ketorolac during cataract surgery compared with postoperative topical steroids in reducing the incidence of postoperative clinical cystoid macular edema (CME) confirmed via optical coherence tomography (OCT), breakthrough iritis, pain, and photophobia." | 7.96 | Effect of intracameral phenylephrine 1.0%-ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery. ( Bedi, R; Visco, DM, 2020) |
| " We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac." | 7.83 | Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016) |
| "To study the association between ketorolac use and postoperative complications." | 7.83 | Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery. ( Alfonso-Cristancho, R; Beck, SJ; Flum, DR; Hakkarainen, TW; Kotagal, M; Simianu, VV, 2016) |
| "1% and dosed 4 times a day starting 1 day before surgery and continuing for 4 weeks." | 6.77 | Prophylactic nepafenac and ketorolac versus placebo in preventing postoperative macular edema after uneventful phacoemulsification. ( Almeida, DR; Bakar, SN; El-Defrawy, SR; Khan, Z; Rahim, K; Urton, T; Xing, L, 2012) |
| "0001) and required twice the rescue dosage (p = 0." | 6.68 | Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine. ( Bean-Lijewski, JD; Hunt, RD, 1996) |
| "Antithrombotic agent usage, postoperative pain, and two or more doses of ketorolac postoperatively were identified as independent risk factors for PH." | 5.51 | Perioperative risk factors for post-thyroidectomy hematoma: Significance of pain and ketorolac usage. ( Ahn, SH; Jeong, WJ; Jung, YH; Kim, Y; Lee, M; Rhee, J, 2019) |
| "Participants scheduled for cataract removal were randomized to 1 of 5 anti-inflammatory prophylactic regimens: eye drops with a combination of prednisolone, 1%, and ketorolac tromethamine, 0." | 5.41 | Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial. ( Erichsen, JH; Forman, JL; Forslund Jacobsen, M; Holm, LM; Kessel, L, 2021) |
| " We sought to determine if the use of intraoperative ketorolac as part of a multimodal ERAS protocol increased the risk of bleeding complications in breast surgery." | 5.30 | Intraoperative Ketorolac Use Does Not Increase the Risk of Bleeding in Breast Surgery. ( Andaz, C; Borgen, P; Flom, P; Fortes, TA; Manasseh, DM; Rojas, KE, 2019) |
| "A total 91 subjects scheduled to undergo cataract operation were randomized into three groups: Group 1, pre/postoperative bromfenac 0." | 5.20 | The Effects of Two Non-Steroidal Anti-Inflammatory Drugs, Bromfenac 0.1% and Ketorolac 0.45%, on Cataract Surgery. ( Chung, BH; Jung, JW; Kim, EK; Kim, TI; Seo, KY, 2015) |
| "Between July 2005 and October 2007, 61 consecutive medically uncontrolled glaucoma patients scheduled for first-time trabeculectomy were randomized to 1 of 3 study topical medication groups: nonsteroidal anti-inflammatory drugs (ketorolac), steroids (fluorometholone), or placebo (artificial tears)." | 5.14 | Preoperative nonsteroidal anti-inflammatory drug or steroid and outcomes after trabeculectomy: a randomized controlled trial. ( Breusegem, C; Fieuws, S; Renier, C; Spielberg, L; Stalmans, I; Van de Veire, S; Van Ginderdeuren, R; Vandewalle, E; Zeyen, T, 2010) |
| "We studied the efficacy of ketorolac, a prostaglandin synthesis inhibitor, in the treatment of bladder spasm after ureteroneocystostomy (antireflux operation)." | 5.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| "This study did not demonstrate a difference in the ability of diclofenac or ketorolac ophthalmic solutions to prevent PCO following cataract extraction and implantation of an intraocular lens." | 5.09 | Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation. ( Dolan, BJ; Flach, AJ, 2000) |
| "To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning." | 5.08 | Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 5.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "We studied the comparative effects of ketorolac versus bupivacaine supplementation of hydromorphone (HM) patient-controlled epidural analgesia (PCEA) on the HM requirement, postoperative pain, and pulmonary function in 62 consenting patients after thoracotomy procedures." | 5.08 | Effects of ketorolac versus bupivacaine coadministration during patient-controlled hydromorphone epidural analgesia after thoracotomy procedures. ( Bossard, RF; Singh, H; White, PF; Yeatts, RW, 1997) |
| "This double-blind randomized trial assessed the effect of adding an intravenous continuous infusion of ketorolac to a patient-controlled analgesia (PCA) morphine regimen on analgesia, heart rate, arterial blood pressure, and postoperative myocardial ischemia." | 5.08 | The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty. ( Badner, NH; Beattie, WS; Buckley, N; Chan, V; Etches, R; Girard, M; Parsons, D; Warriner, CB, 1997) |
| " Despite ondansetron and droperidol prophylaxis, there was still a substantial amount of nausea and vomiting after desflurane." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 5.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 5.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| "As a new ophthalmic non-steroidal anti-inflammatory drug (NSAID) with prodrug structure, Nepafenac was supposed to have a better efficacy than conventional NSAIDs both in patients' tolerability and ocular inflammation associated with cataract surgery." | 4.95 | Comparison of the efficacy and patients' tolerability of Nepafenac and Ketorolac in the treatment of ocular inflammation following cataract surgery: A meta-analysis of randomized controlled trials. ( Chen, Y; Wang, E; Xia, S; Zhao, X, 2017) |
| "To assess the effectiveness of ketorolac vs control for prevention of acute pseudophakic cystoid macular edema (CME)." | 4.88 | Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review. ( Cordero-Coma, M; Gallagher, MJ; Yilmaz, T, 2012) |
| "Topical NSAIDs were found to be more effective in controlling CME, pain, iritis, and photophobia after cataract surgery compared with the intracanalicular dexamethasone insert in the presence of intracameral phenylephrine/ketorolac." | 4.31 | Comparison of postcataract surgery anti-inflammatory regimens on the incidence of cystoid macular edema, iritis, pain, and photophobia. ( Visco, DM, 2023) |
| "This study demonstrated 40% mortality reduction with intravenous ketorolac following open abdominal aortic aneurysm repair." | 4.02 | Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair. ( Al-Nouri, O; Locham, S; Malas, MB; Naazie, IN; Nejim, B; Weaver, ML, 2021) |
| " There is conflicting evidence that ketorolac use in inflammatory bowel disease (IBD) may precipitate disease flares and postoperative complications." | 3.96 | Ketorolac after colectomy for ulcerative colitis in children: An analysis of opioid utilization and postoperative complications. ( Deneau, M; Guthery, SL; Short, SS; Taylor, MA; West, WB, 2020) |
| "To assess the effectiveness of intracameral phenylephrine-ketorolac during cataract surgery compared with postoperative topical steroids in reducing the incidence of postoperative clinical cystoid macular edema (CME) confirmed via optical coherence tomography (OCT), breakthrough iritis, pain, and photophobia." | 3.96 | Effect of intracameral phenylephrine 1.0%-ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery. ( Bedi, R; Visco, DM, 2020) |
| " We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac." | 3.83 | Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016) |
| "To study the association between ketorolac use and postoperative complications." | 3.83 | Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery. ( Alfonso-Cristancho, R; Beck, SJ; Flum, DR; Hakkarainen, TW; Kotagal, M; Simianu, VV, 2016) |
| "We aimed to identify the risk factors for acute kidney injury in infants who have received ketorolac after a cardiac surgical procedure by identifying patients with a > or = 50% increase in serum creatinine from baseline and matching them by age with three controls that had < 50% increase in serum creatinine." | 3.79 | Ketorolac-associated renal morbidity: risk factors in cardiac surgical infants. ( Cabrera, A; Moffett, BS, 2013) |
| "This case report describes postoperative, reversible renal dysfunction and hypertension in a 5-year-old healthy boy after administration of relevant doses of ketorolac during anaesthesia." | 3.75 | [Ketorolac as a possible cause of reversible renal dysfunction in a 5-year-old child]. ( Knudsen, SM; Mantoni, T; Walther-Larsen, S, 2009) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "1% and dosed 4 times a day starting 1 day before surgery and continuing for 4 weeks." | 2.77 | Prophylactic nepafenac and ketorolac versus placebo in preventing postoperative macular edema after uneventful phacoemulsification. ( Almeida, DR; Bakar, SN; El-Defrawy, SR; Khan, Z; Rahim, K; Urton, T; Xing, L, 2012) |
| "The ketorolac dose was modified, after six patients had been studied, based on new product information recommending a maximum of 120 mg ketorolac over 24 h." | 2.70 | The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery. ( Evans, SF; Paech, MJ; Pavy, TJ, 2001) |
| "Treatment with ketorolac after abdominal myomectomy results in a statistically significant reduction in the rate of febrile episodes." | 2.70 | The effect of ketorolac on postoperative febrile episodes in patients after abdominal myomectomy. ( Ascher-Walsh, C; Blanco, J; Held, BI; Michels, A, 2002) |
| "Postoperative pain was assessed by self-report 1." | 2.69 | Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy. ( Ostergaard, D; Rømsing, J; Valentin, N; Walther-Larsen, S, 1998) |
| "Treatment with ketorolac is completed during hospitalization; therefore, compliance is ensured." | 2.68 | Ketorolac prophylaxis against heterotopic ossification after hip replacement. ( Pritchett, JW, 1995) |
| "0001) and required twice the rescue dosage (p = 0." | 2.68 | Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine. ( Bean-Lijewski, JD; Hunt, RD, 1996) |
| "Ketorolac is a parenteral nonsteroidal antiinflammatory drug (NSAID)." | 2.68 | Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients. ( Bosek, V; Cox, CE, 1996) |
| "Ketorolac and metamizol were found to be equally safe and effective in reducing postoperative pain after plastic surgery." | 2.68 | A controlled, randomized, double-blind study of ketorolac for postoperative analgesia after plastic surgery. ( Amorrortu-Velayos, J; De Andrés, J; González-Martínez, R; Marín-Bertolín, S; Valia Vera, JC, 1997) |
| "Operative blood losses, postoperative pain, sedation, and on-demand morphine consumption (patient-controlled analgesia [PCA]) were measured." | 2.67 | The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response. ( Marinangeli, F; Niv, D; Panella, L; Piroli, A; Varrassi, G; Varrassi, S; Wolman, I, 1994) |
| "No cases of post-operative renal failure requiring dialysis were described." | 2.41 | Effects of nonsteroidal anti-inflammatory drugs on post-operative renal function in adults. ( Cooper, MG; Craig, JC; Keneally, JP; Knight, JF; Lee, A, 2000) |
| "Ketorolac has been added to many of these protocols, but few studies have examined its effects independently." | 1.91 | Scheduled Postoperative Ketorolac Does Not Decrease Opiate Use following Free Flap Breast Reconstruction. ( Agarwal, J; Anderson, E; Clinker, C; Eddington, D; Kwok, AC; Marquez, JL; Moss, WD; Sudduth, JD, 2023) |
| "A mouse model of endometriosis recurrence caused by spillage and dissemination was first established using 24 female Balb/c mice." | 1.62 | Preoperative and perioperative intervention reduces the risk of recurrence of endometriosis in mice caused by either incomplete excision or spillage and dissemination. ( Chen, Y; Guo, SW; Liu, X, 2021) |
| "To determine the rate of postoperative cystoid macular edema (CME) in patients undergoing cataract surgery treated with intraoperative intracameral and postoperative topical nonsteroidal antiinflammatory drugs (NSAIDs) without steroids." | 1.56 | Rate of pseudophakic cystoid macular edema using intraoperative and topical nonsteroidal antiinflammatory drugs alone without steroids. ( Hess, J; Kauffman, L; Walter, K, 2020) |
| "Antithrombotic agent usage, postoperative pain, and two or more doses of ketorolac postoperatively were identified as independent risk factors for PH." | 1.51 | Perioperative risk factors for post-thyroidectomy hematoma: Significance of pain and ketorolac usage. ( Ahn, SH; Jeong, WJ; Jung, YH; Kim, Y; Lee, M; Rhee, J, 2019) |
| "This may also explain sudden confusion and dementia for the elderly after surgery." | 1.48 | Breast Cancer Relapse, Post-Surgical Confusion, and Dementia in the Elderly: An Unexpected Connection but with the Same Proposed Solution. ( Forget, P; Retsky, MW, 2018) |
| "Ketorolac was associated with fewer readmissions (OR, 0." | 1.48 | Postoperative Ketorolac in Breast and Body Contouring Procedures: A Nationwide Claims Analysis. ( Bennett, KG; Chung, KC; Chung, TT; Kelley, BP; Sacks, G; Sears, ED; Waljee, JF, 2018) |
| " Patients' demographic, surgical, and dosing data were collected." | 1.33 | Safety of ketorolac in neonates and infants after cardiac surgery. ( Carberry, KE; Moffett, BS; Mott, AR; Wann, TI, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 28 (31.11) | 18.2507 |
| 2000's | 12 (13.33) | 29.6817 |
| 2010's | 38 (42.22) | 24.3611 |
| 2020's | 12 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Moon, JK | 1 |
| Hwang, R | 1 |
| Balis, FM | 1 |
| Mattei, P | 1 |
| Visco, DM | 2 |
| Orlans, HO | 1 |
| Yazdouni, S | 1 |
| Williamson, TH | 1 |
| Wong, RS | 1 |
| Laidlaw, DAH | 1 |
| Sueda, S | 1 |
| Adkins, A | 1 |
| Dehal, A | 1 |
| Al-Temimi, M | 1 |
| Chen, LH | 1 |
| O'Connor, V | 1 |
| DiFronzo, LA | 1 |
| Sudduth, JD | 1 |
| Moss, WD | 1 |
| Clinker, C | 1 |
| Marquez, JL | 1 |
| Anderson, E | 1 |
| Eddington, D | 1 |
| Agarwal, J | 1 |
| Kwok, AC | 1 |
| Kunstman, JW | 1 |
| Brandt, WS | 1 |
| Azar, SA | 1 |
| Jean, RA | 1 |
| Salem, RR | 1 |
| Walter, K | 1 |
| Kauffman, L | 1 |
| Hess, J | 1 |
| Taylor, MA | 1 |
| West, WB | 1 |
| Guthery, SL | 1 |
| Deneau, M | 1 |
| Short, SS | 1 |
| Bedi, R | 1 |
| Nejim, B | 1 |
| Weaver, ML | 1 |
| Locham, S | 1 |
| Al-Nouri, O | 1 |
| Naazie, IN | 1 |
| Malas, MB | 1 |
| Chen, Y | 2 |
| Liu, X | 1 |
| Guo, SW | 1 |
| Erichsen, JH | 1 |
| Holm, LM | 1 |
| Forslund Jacobsen, M | 1 |
| Forman, JL | 1 |
| Kessel, L | 1 |
| Campochiaro, PA | 1 |
| Han, YS | 1 |
| Mir, TA | 1 |
| Kherani, S | 1 |
| Hafiz, G | 1 |
| Krispel, C | 1 |
| Liu, TYA | 1 |
| Wang, J | 1 |
| Scott, AW | 1 |
| Zimmer-Galler, I | 1 |
| Diakonis, VF | 1 |
| Kontadakis, GA | 1 |
| Anagnostopoulos, AG | 1 |
| Yesilirmak, N | 1 |
| Waren, DP | 1 |
| Cabot, F | 1 |
| Yoo, SH | 1 |
| Donaldson, KE | 1 |
| Rodríguez-García, A | 1 |
| Hernández-Camarena, JC | 1 |
| López-Jaime, GR | 1 |
| Nava-García, JA | 1 |
| Kuchálik, J | 1 |
| Magnuson, A | 1 |
| Tina, E | 1 |
| Gupta, A | 2 |
| Naseem, HU | 1 |
| Dorman, RM | 1 |
| Ventro, G | 1 |
| Rothstein, DH | 1 |
| Vali, K | 1 |
| Kowalsky, SJ | 1 |
| Zenati, MS | 1 |
| Steve, J | 1 |
| Lee, KK | 1 |
| Hogg, ME | 1 |
| Zeh, HJ | 1 |
| Zureikat, AH | 1 |
| Mikhaylov, Y | 1 |
| Weinstein, B | 1 |
| Schrank, TP | 1 |
| Swartz, JD | 1 |
| Ulm, JP | 1 |
| Armstrong, MB | 1 |
| Delaney, KO | 1 |
| Uber, AM | 1 |
| Montez-Rath, ME | 1 |
| Kwiatkowski, DM | 1 |
| Krawczeski, CD | 1 |
| Sutherland, SM | 1 |
| Kelley, BP | 1 |
| Chung, KC | 1 |
| Chung, TT | 1 |
| Bennett, KG | 1 |
| Sacks, G | 1 |
| Sears, ED | 1 |
| Waljee, JF | 1 |
| Retsky, MW | 1 |
| Forget, P | 1 |
| Hovanesian, J | 1 |
| Holland, E | 1 |
| Tabrizian, P | 1 |
| Giacca, M | 1 |
| Prigoff, J | 1 |
| Tran, B | 1 |
| Holzner, ML | 1 |
| Chin, E | 1 |
| Palese, M | 1 |
| Herron, D | 1 |
| Arvelakis, A | 1 |
| Rudow, DL | 1 |
| Florman, S | 1 |
| Shapiro, R | 1 |
| Rojas, KE | 1 |
| Fortes, TA | 1 |
| Flom, P | 1 |
| Manasseh, DM | 1 |
| Andaz, C | 1 |
| Borgen, P | 1 |
| Lee, M | 1 |
| Rhee, J | 1 |
| Kim, Y | 1 |
| Jung, YH | 1 |
| Ahn, SH | 1 |
| Jeong, WJ | 1 |
| Turan-Vural, E | 1 |
| Halili, E | 1 |
| Serin, D | 1 |
| Tzelikis, PF | 1 |
| Vieira, M | 1 |
| Hida, WT | 1 |
| Motta, AF | 1 |
| Nakano, CT | 1 |
| Nakano, EM | 1 |
| Alves, MR | 1 |
| Sitkin, SI | 1 |
| Davydova, OB | 1 |
| Kostin, IO | 1 |
| Gasparian, AL | 1 |
| Lee, TH | 1 |
| Choi, W | 1 |
| Ji, YS | 1 |
| Yoon, KC | 1 |
| Kotagal, M | 1 |
| Hakkarainen, TW | 1 |
| Simianu, VV | 1 |
| Beck, SJ | 1 |
| Alfonso-Cristancho, R | 1 |
| Flum, DR | 1 |
| Brown, V | 1 |
| Martin, J | 1 |
| Magee, D | 1 |
| Warth, LC | 1 |
| Noiseux, NO | 1 |
| Hogue, MH | 1 |
| Klaassen, AL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Drop-less Surgery Compared to Topical NSAID Alone and Combination of Steroid and NSAID on Central Macular Thickness After Cataract Surgery, a Randomized Controlled Trial[NCT03383328] | Phase 4 | 470 participants (Actual) | Interventional | 2018-02-01 | Completed | ||
| Comparison of Ketorolac Tromethamine 0.4% and Nepafenac 0.1% for the Prevention of Cystoid Macular Edema After Phacoemulsification: Prospective Randomized Double-masked Study[NCT02084576] | Phase 4 | 40 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| Evaluating the Efficacy, Compliance, and Patient Satisfaction of a New Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population[NCT05157113] | Phase 4 | 70 participants (Anticipated) | Interventional | 2022-05-31 | Recruiting | ||
| Effect of Toradol on Post-operative Foot and Ankle Healing[NCT03727048] | Phase 4 | 128 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| The Effect of Preoperative Topical Ketorolac 0.45% on Aqueous Cytokine Levels and Macular Thickness in Diabetic and Non Diabetic Patients Undergoing Cataract Surgery[NCT02646072] | Phase 4 | 80 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Protein Profile of Immunoregulatory Factors in Diabetic Cataract[NCT01832311] | Phase 4 | 61 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Colchicine for the Prevention of Atrial Fibrillation Recurrence After Electrical Cardioversion of Persistent Atrial Fibrillation.[NCT02582190] | Phase 3 | 0 participants (Actual) | Interventional | 2017-12-02 | Withdrawn (stopped due to Investigational Medicinal Product Supplies) | ||
| Continuous Infusion Versus Intermittent Ketorolac for Postoperative Pain Control in Pediatric Cardiac Surgery Patients[NCT04040452] | Phase 4 | 166 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| A Pilot Study Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT02973958] | Phase 1 | 30 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| A Randomized Control Trial Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT04646967] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-11-25 | Recruiting | ||
| Prospective Evaluation of the Effects of IV Ketorolac on Platelet Function Post-Cesarean Delivery[NCT03805607] | Phase 4 | 40 participants (Actual) | Interventional | 2021-01-18 | Active, not recruiting | ||
| A Prospective, Randomized, Control Trial of Ketorolac Versus Placebo on Opioid Analgesic Use, Estimated Blood Loss and Complications Following Cesarean Delivery With Epidural Morphine[NCT02509312] | Phase 4 | 70 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total doses of medications to treat pruritus (opioid side-effect) including ondansetron and promethazine. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Corrected change in Hct on POD1. Performed by subtracting POD1 Hct from POD0 Hct. Correction for transfusion by further subtracting 3 per unit of pRBC transfused to account for the typical change seen per unit transfused. (NCT02509312)
Timeframe: POD1
| Intervention | mg/dl (Mean) |
|---|---|
| Ketorolac | -5.1 |
| Placebo | -3.5 |
Estimation of blood loss during surgery (NCT02509312)
Timeframe: Immediately post-op
| Intervention | ml (Median) |
|---|---|
| Ketorolac | 900 |
| Placebo | 800 |
Rate of Post-Partum Hemorrhage between groups during the first 24 hours pst-partum. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketorolac | 7 |
| Placebo | 4 |
Total doses of medications to treat pruritus (opioid side-effect) including diphenhydramine, nalbuphine and naloxone. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Total hydromorphone doses in mg in the first 24 hours post-partum. (NCT02509312)
Timeframe: 0 - 24 hours post-partum.
| Intervention | mg (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0.2 |
Total number of Units of Packed Reb Blood Cell Transfused in intra-op until 24 hours post-partum. (NCT02509312)
Timeframe: Intra-op until 24 hours post-partum.
| Intervention | units of pRBCs (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Total number of uterotonic doses including methylergonovine, carboprost and misoprostol. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Pain score post-Cesarean Delivery using 11-point numerical rating scale (NRS): 0-10 where 0 is no pain and 10 is the worst pain imaginable (NCT02509312)
Timeframe: Up to 24 hours post-cesarean delivery
| Intervention | units on NRS (Median) | |||||
|---|---|---|---|---|---|---|
| Baseline | 15 mins | 1 hour | 6 hours | 12 hours | 24 hours | |
| Ketorolac | 0 | 0 | 0 | 1 | 2 | 4.5 |
| Placebo | 0 | 0 | 0 | 3 | 3.5 | 5.5 |
Percentile change in diastolic Blood Pressure at 6,12, and 24 hours for each patient's baseline defined by immediate post-op PACU vitals. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Percent change (Mean) | ||
|---|---|---|---|
| 6 hours | 12 hours | 24 hours | |
| Ketorolac | 12.30 | 8.8 | 12.0 |
| Placebo | 7.6 | 8.8 | 11.1 |
Percentile change in Systolic Blood Pressure at 6,12, and 24 hours for each patient's baseline defined by immediate post-op PACU vitals. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Percent change (Mean) | ||
|---|---|---|---|
| 6 hours | 12 hours | 24 hours | |
| Ketorolac | -2.0 | -9.10 | -5.9 |
| Placebo | -0.6 | -2.85 | -3.5 |
5 reviews available for ketorolac and Postoperative Complications
| Article | Year |
|---|---|
Comparison of the efficacy and patients' tolerability of Nepafenac and Ketorolac in the treatment of ocular inflammation following cataract surgery: A meta-analysis of randomized controlled trials.
Topics: Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Cataract Extraction; H | 2017 |
High-dose ketorolac affects adult spinal fusion: a meta-analysis of the effect of perioperative nonsteroidal anti-inflammatory drugs on spinal fusion.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Pain, Postoperative; Perioperativ | 2011 |
Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Humans; Ketorolac; Macu | 2012 |
New antiemetic drugs.
Topics: Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; An | 1995 |
Effects of nonsteroidal anti-inflammatory drugs on post-operative renal function in adults.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Diclofenac; Humans; Ketorolac; Kidney; P | 2000 |
38 trials available for ketorolac and Postoperative Complications
| Article | Year |
|---|---|
Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extracti | 2021 |
Increased Frequency of Topical Steroids Provides Benefit in Patients With Recalcitrant Postsurgical Macular Edema.
Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Dose-Re | 2017 |
Effects of Short-term Preoperative Topical Ketorolac on Pupil Diameter in Eyes Undergoing Femtosecond Laser-Assisted Capsulotomy.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dose-Resp | 2017 |
Does local infiltration analgesia reduce peri-operative inflammation following total hip arthroplasty? A randomized, double-blind study.
Topics: Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; | 2017 |
Tolerability and toxicity of topically applied nepafenac 0.3% compared with generic ketorolac 0.5.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Drug Tolerance; Female; Follow-Up | 2019 |
Intraoperative Ketorolac Use Does Not Increase the Risk of Bleeding in Breast Surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasm | 2019 |
Assessing the effects of ketorolac and acetazolamide on macular thickness by optical coherence tomography following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Analys | 2014 |
Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of cystoid macular oedema after phacoemulsification: prospective placebo-controlled randomised study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneac | 2015 |
[Use of analgesia and sedation in dental implantology in patients with concomitant hypertension].
Topics: Anesthesia, Dental; Anesthesia, Local; Blood Pressure; Conscious Sedation; Dental Implantation; Fema | 2015 |
The Effects of Two Non-Steroidal Anti-Inflammatory Drugs, Bromfenac 0.1% and Ketorolac 0.45%, on Cataract Surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Cataract; Cataract Extr | 2015 |
Effect of topical ketorolac 0.4%, nepafenac 0.1%, and bromfenac 0.09% on postoperative inflammation using laser flare photometry in patients having phacoemulsification.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Be | 2015 |
Efficacy and tolerability of preservative-free and preserved diclofenac and preserved ketorolac eyedrops after cataract surgery.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Diclofenac | 2010 |
Preoperative nonsteroidal anti-inflammatory drug or steroid and outcomes after trabeculectomy: a randomized controlled trial.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihyper | 2010 |
Ketorolac plus tobramycin/dexamethasone versus tobramycin/dexamethasone after uneventful phacoemulsification surgery: a randomized controlled trial.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Corneal Edema; Dexamethasone; | 2011 |
Pre-emptive analgesic effectiveness of meloxicam versus tramadol after mandibular third molar surgery: a pilot study.
Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; | 2012 |
Prophylactic nepafenac and ketorolac versus placebo in preventing postoperative macular edema after uneventful phacoemulsification.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Double-Blind Me | 2012 |
The effect of ketorolac on postoperative febrile episodes in patients after abdominal myomectomy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Fever; Gynecologic Surg | 2002 |
Efficacy of nonsteroidal anti-inflammatory medications for prevention of atrial fibrillation following coronary artery bypass graft surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Atrial Fibrillation; Coronary Artery Bypass; Female; | 2004 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Ketorolac prophylaxis against heterotopic ossification after hip replacement.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female | 1995 |
Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning.
Topics: Analgesics, Non-Narcotic; Bupivacaine; Combined Modality Therapy; Female; Humans; Ketorolac; Laparos | 1995 |
The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia; Child; Child, P | 1995 |
Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Method; Female; Hu | 1994 |
A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children.
Topics: Age Factors; Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Metho | 1994 |
The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response.
Topics: Analgesics; Blood Glucose; Cholecystectomy; Creatinine; Double-Blind Method; Elective Surgical Proce | 1994 |
Use of ketorolac and fentanyl during outpatient gynecologic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Chemotherapy, Adjuvant; Drug Therapy, Combination | 1993 |
Effects of ketorolac on postoperative analgesia and ventilatory function after laparoscopic cholecystectomy.
Topics: Adolescent; Adult; Aged; Analgesics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Hum | 1993 |
Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bleeding Time; Child; Child, Preschool; Double-Blind M | 1996 |
Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Analysis of Variance; Breast Neoplasms; Double-Bl | 1996 |
Effects of ketorolac versus bupivacaine coadministration during patient-controlled hydromorphone epidural analgesia after thoracotomy procedures.
Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Bupiva | 1997 |
The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; E | 1997 |
A controlled, randomized, double-blind study of ketorolac for postoperative analgesia after plastic surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone | 1997 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 1998 |
Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cystostomy; Double-Blind Method; H | 2000 |
Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extraction; Chi | 2000 |
The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi | 2001 |
The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi | 2001 |
The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi | 2001 |
The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi | 2001 |
47 other studies available for ketorolac and Postoperative Complications
| Article | Year |
|---|---|
An enhanced recovery after surgery protocol in children who undergo nephrectomy for Wilms tumor safely shortens hospital stay.
Topics: Child; Child, Preschool; Enhanced Recovery After Surgery; Humans; Ketorolac; Kidney Neoplasms; Lengt | 2022 |
Comparison of postcataract surgery anti-inflammatory regimens on the incidence of cystoid macular edema, iritis, pain, and photophobia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Dexamethasone; Humans; Incidence; Iritis; Ketorol | 2023 |
A Novel Postoperative Drop Regimen Reduces Risk of Ocular Hypertension Following Pars Plana Vitrectomy.
Topics: Dexamethasone; Humans; Ketorolac; Ocular Hypertension; Postoperative Complications; Retrospective St | 2023 |
Effects of ketorolac on complications and postoperative pancreatic fistula in patients undergoing pancreatectomy.
Topics: Female; Humans; Ketorolac; Male; Pancreas; Pancreatectomy; Pancreatic Fistula; Postoperative Complic | 2023 |
Scheduled Postoperative Ketorolac Does Not Decrease Opiate Use following Free Flap Breast Reconstruction.
Topics: Free Tissue Flaps; Humans; Ketorolac; Mammaplasty; Opiate Alkaloids; Pain, Postoperative; Postoperat | 2023 |
Comprehensive Analysis of the Effect of Ketorolac Administration after Pancreaticoduodenectomy.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood | 2020 |
Rate of pseudophakic cystoid macular edema using intraoperative and topical nonsteroidal antiinflammatory drugs alone without steroids.
Topics: Administration, Ophthalmic; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; | 2020 |
Ketorolac after colectomy for ulcerative colitis in children: An analysis of opioid utilization and postoperative complications.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Colectomy; Colitis, Ulcerative; | 2020 |
Effect of intracameral phenylephrine 1.0%-ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extraction; Cohort Studies; Humans; Irit | 2020 |
Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair.
Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aortic Aneurysm, Abdomin | 2021 |
Preoperative and perioperative intervention reduces the risk of recurrence of endometriosis in mice caused by either incomplete excision or spillage and dissemination.
Topics: Animals; Aprepitant; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Diterpen | 2021 |
Effect of Topical Nonsteroidal Anti-inflammatory Drugs on Pupillary Size During Uncomplicated Cataract Surgery.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Double-B | 2017 |
Safety of perioperative ketorolac administration in pediatric appendectomy.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Appendectomy; Child; Child, Preschool; Female; | 2017 |
Ketorolac use may increase risk of postoperative pancreatic fistula after pancreaticoduodenectomy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ketorolac; Male; Middle Aged; Pancrea | 2018 |
Ketorolac and Hematoma Incidence in Postmastectomy Implant-Based Breast Reconstruction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast Implants; Breast Neoplasms; Female; Hematoma; Humans | 2018 |
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Crit | 2018 |
Postoperative Ketorolac in Breast and Body Contouring Procedures: A Nationwide Claims Analysis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Contouring; Breast; Female; Hematoma; Hum | 2018 |
Breast Cancer Relapse, Post-Surgical Confusion, and Dementia in the Elderly: An Unexpected Connection but with the Same Proposed Solution.
Topics: Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Confusi | 2018 |
Renal Safety of Intravenous Ketorolac Use After Donor Nephrectomy.
Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Female; Hum | 2019 |
Perioperative risk factors for post-thyroidectomy hematoma: Significance of pain and ketorolac usage.
Topics: Adult; Case-Control Studies; Female; Follow-Up Studies; Hematoma; Humans; Incidence; Ketorolac; Male | 2019 |
Comparison of ketorolac 0.45% versus diclofenac 0.1% for macular thickness and volume after uncomplicated cataract surgery.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Intrao | 2016 |
Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Digestive System Surgical Procedures; Emergencies; Female; | 2016 |
A rare case of subcapsular liver haematoma following laparoscopic cholecystectomy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Cholecystectomy, Laparoscopic; Cholelithias | 2015 |
Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthro | 2016 |
Comparative Effectiveness of Three Prophylactic Strategies to Prevent Clinical Macular Edema after Phacoemulsification Surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofena | 2015 |
Treating inflammation after lens surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Benzophenones; Bromobenzenes; Endophthal | 2015 |
A Non-Narcotic Pathway for the Management of Postoperative Pain Following Pediatric Robotic Pyeloplasty.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory | 2017 |
The effect of ketorolac on anteroposterior knee laxity after anterior cruciate ligament reconstruction.
Topics: Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Anti-Inflammatory Agents, Non-Stero | 2008 |
[Ketorolac as a possible cause of reversible renal dysfunction in a 5-year-old child].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Hernia, Umbilical; Humans; Hypertension; | 2009 |
Ketorolac improves graft patency after coronary artery bypass grafting: a propensity-matched analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Artery Bypass; Coronar | 2011 |
The efficacy of multimodal high-volume wound infiltration in primary total hip replacement.
Topics: Adult; Aged; Aged, 80 and over; Amides; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Ag | 2011 |
Does ketorolac improve graft patency after coronary artery bypass grafting?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Artery Bypass; Coronary Dise | 2012 |
Ketorolac-associated renal morbidity: risk factors in cardiac surgical infants.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; | 2013 |
Central serous retinopathy masquerading as sympathetic ophthalmia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Eye Injuries, Penetrating; | 2003 |
Safety of ketorolac in neonates and infants after cardiac surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Urea Nitrogen; Cardiac Surgical Procedures; Cohort St | 2006 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
Ketorolac prevents postoperative small intestinal ileus in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Transit; Injections, Intraperiton | 1993 |
Diclofenac and post-tonsillectomy haemorrhage.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hemorrhage; Humans; K | 1995 |
Ketorolac and strabismus surgery.
Topics: Analgesics, Non-Narcotic; Humans; Ketorolac; Postoperative Complications; Strabismus; Tolmetin; Vomi | 1996 |
Differential effect of indomethacin and ketorolac on postoperative ileus in rats.
Topics: Animals; Disease Models, Animal; Indomethacin; Intestinal Obstruction; Ketorolac; Nitric Oxide; Nitr | 1998 |
Does ketorolac cause postoperative renal failure: how do we assess the evidence?
Topics: Acute Kidney Injury; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Bas | 1998 |
Incidence of hematoma associated with ketorolac after TRAM flap breast reconstruction.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 2001 |
Subjective and objective comparison of critical care pathways for open donor nephrectomy.
Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, No | 2002 |
Bleeding diathesis after perioperative ketorolac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Humans; Ketorolac; Postoperati | 1992 |
Bleeding diathesis after perioperative ketorolac.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Humans; Ketorolac; Male; | 1992 |
Bleeding diathesis after perioperative ketorolac.
Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Hemorrhagic Disorders; Humans; Ketorolac; | 1991 |
Postoperative hematomas associated with Toradol.
Topics: Analgesics; Hematoma; Humans; Ketorolac; Postoperative Complications; Tolmetin | 1991 |