Page last updated: 2024-10-29

ketorolac and Musculoskeletal Pain

ketorolac has been researched along with Musculoskeletal Pain in 4 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.

Research Excerpts

ExcerptRelevanceReference
"Ketorolac is useful in acute pain management to avoid opiate-related complications; however, some surgeons fear associated acute kidney injury (AKI) and bleeding despite a paucity of literature on ketorolac use in trauma patients."8.02Ketorolac Use for Pain Management in Trauma Patients With Rib Fractures Does not Increase of Acute Kidney Injury or Incidence of Bleeding. ( Chao, E; DeHaan, S; Jureller, M; Kaban, JM; Laikhram, D; Lewis, E; Reddy, SH; Simon, R; Stone, ME; Torabi, J, 2021)
"Adhesive capsulitis is painful condition, associated with gradual loss of active and passive shoulder motion that has a disabling capability."6.90Comparison of intra articular NSAID (ketorolac) injection versus hyaluronic acid injection for the mean decrease of pain score (according to UCLA shoulder rating scale) in the management of adhesive capsulitis. ( Akhtar, M; Cheema, OI; Nadeem, MR; Nadeem, RDA; Shah Gillani, SF, 2019)
"Ketorolac is useful in acute pain management to avoid opiate-related complications; however, some surgeons fear associated acute kidney injury (AKI) and bleeding despite a paucity of literature on ketorolac use in trauma patients."4.02Ketorolac Use for Pain Management in Trauma Patients With Rib Fractures Does not Increase of Acute Kidney Injury or Incidence of Bleeding. ( Chao, E; DeHaan, S; Jureller, M; Kaban, JM; Laikhram, D; Lewis, E; Reddy, SH; Simon, R; Stone, ME; Torabi, J, 2021)
"Adhesive capsulitis is painful condition, associated with gradual loss of active and passive shoulder motion that has a disabling capability."2.90Comparison of intra articular NSAID (ketorolac) injection versus hyaluronic acid injection for the mean decrease of pain score (according to UCLA shoulder rating scale) in the management of adhesive capsulitis. ( Akhtar, M; Cheema, OI; Nadeem, MR; Nadeem, RDA; Shah Gillani, SF, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Torabi, J1
Kaban, JM1
Lewis, E1
Laikhram, D1
Simon, R1
DeHaan, S1
Jureller, M1
Chao, E1
Reddy, SH1
Stone, ME1
Turner, NJ1
Long, DA1
Bongiorno, JR1
Katoski, TP1
Jin, LM1
Horsch, JP1
Ahern, BJ1
Akhtar, M1
Nadeem, RDA1
Shah Gillani, SF1
Cheema, OI1
Nadeem, MR1
Vygonskaya, MV1
Filatova, EG1

Reviews

1 review available for ketorolac and Musculoskeletal Pain

ArticleYear
[Muscle-skeletal pain].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2016, Volume: 116, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Combined Modality Therapy; Humans; Ketorolac;

2016

Trials

2 trials available for ketorolac and Musculoskeletal Pain

ArticleYear
Comparing two doses of intramuscular ketorolac for treatment of acute musculoskeletal pain in a military emergency department.
    The American journal of emergency medicine, 2021, Volume: 50

    Topics: Acute Pain; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital;

2021
Comparison of intra articular NSAID (ketorolac) injection versus hyaluronic acid injection for the mean decrease of pain score (according to UCLA shoulder rating scale) in the management of adhesive capsulitis.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Epin

2019

Other Studies

1 other study available for ketorolac and Musculoskeletal Pain

ArticleYear
Ketorolac Use for Pain Management in Trauma Patients With Rib Fractures Does not Increase of Acute Kidney Injury or Incidence of Bleeding.
    The American surgeon, 2021, Volume: 87, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Stero

2021