ketorolac has been researched along with Kidney Stones in 9 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The parameters considered as prognostic factors were pain relief with ketorolac (K) or ketorolac plus opiate treatment (KO), and stone size (>or= or <6 mm)." | 3.71 | Comparison of stone size and response to analgesic treatment in predicting outcome of patients with renal colic. ( Prina, LD; Rancatore, E; Secic, M; Weber, RE, 2002) |
| "Opioids are often used to manage postoperative pain." | 3.11 | Optimizing pain management following kidney stone surgery: can we avoid narcotics? ( Ahn, J; Cuartas, P; Demasi, M; Feiertag, N; Kim, M; Laudano, M; Loloi, J; Mengotto, A; Segall, M; Stern, J; Watts, K, 2022) |
| "For ESWL treatment of kidney stones of 20 mm or less and ureteral stones of 15 mm or less, we suggest local analgesia with topical Luan and intramuscular analgesia." | 1.32 | ESWL: Comparing two analgesic techniques. Our experience. ( Aquilino, M; Bonaccorsi, A; Guzzardi, F; Lazzara, A; Motta, M; Saita, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Demasi, M | 1 |
| Segall, M | 1 |
| Mengotto, A | 1 |
| Cuartas, P | 1 |
| Feiertag, N | 1 |
| Loloi, J | 1 |
| Ahn, J | 1 |
| Kim, M | 1 |
| Laudano, M | 1 |
| Stern, J | 1 |
| Watts, K | 1 |
| Chew, BH | 1 |
| Rebullar, KA | 1 |
| Harriman, D | 1 |
| McDougall, E | 1 |
| Paterson, RF | 1 |
| Lange, D | 1 |
| Prina, LD | 1 |
| Rancatore, E | 1 |
| Secic, M | 1 |
| Weber, RE | 1 |
| Saita, A | 1 |
| Bonaccorsi, A | 1 |
| Aquilino, M | 1 |
| Guzzardi, F | 1 |
| Lazzara, A | 1 |
| Motta, M | 1 |
| McDougal, WS | 1 |
| Bergus, GR | 1 |
| Smally, AJ | 1 |
| Mofenson, HC | 1 |
| Caraccio, TR | 1 |
| Benson, DM | 1 |
2 trials available for ketorolac and Kidney Stones
| Article | Year |
|---|---|
Optimizing pain management following kidney stone surgery: can we avoid narcotics?
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Constipation; Humans; Ketorolac; Kidney Calculi; Narco | 2022 |
Pain relief for renal colic.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-Blind Method; Drug | 1996 |
7 other studies available for ketorolac and Kidney Stones
| Article | Year |
|---|---|
Percuflex Helical Ureteral Stents Significantly Reduce Patient Analgesic Requirements Compared to Control Stents.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug-Eluting Stents; Equipment Des | 2017 |
Comparison of stone size and response to analgesic treatment in predicting outcome of patients with renal colic.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Emergency Service, Hospital; Fem | 2002 |
ESWL: Comparing two analgesic techniques. Our experience.
Topics: Administration, Topical; Adult; Aged; Analgesia; Betamethasone; Drug Therapy, Combination; Female; H | 2004 |
Reversible acute renal failure after unilateral extracorporeal shock-wave lithotripsy.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Kidney; Kidney Calc | 2005 |
Analgesia in renal colic.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Humans; Ketorolac; Kidney Calculi; | 1997 |
Analgesia in renal colic.
Topics: Acute Kidney Injury; Analgesics, Non-Narcotic; Colic; Humans; Ketorolac; Kidney Calculi; Tolmetin | 1997 |
Analgesia in renal colic.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Drug Therapy, Combination; Humans; Ketorolac; K | 1997 |