Page last updated: 2024-10-29

ketorolac and Ischemia

ketorolac has been researched along with Ischemia in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lopez, MG1
Silva, BM1
Joyner, MJ1
Casey, DP1
Jacob, E1
Miaskowski, C1
Savedra, M1
Beyer, JE1
Treadwell, M1
Styles, L1

Trials

1 trial available for ketorolac and Ischemia

ArticleYear
Roles of nitric oxide and prostaglandins in the hyperemic response to a maximal metabolic stimulus: redundancy prevails.
    European journal of applied physiology, 2013, Volume: 113, Issue:6

    Topics: Blood Pressure; Enzyme Inhibitors; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Isch

2013

Other Studies

1 other study available for ketorolac and Ischemia

ArticleYear
Management of vaso-occlusive pain in children with sickle cell disease.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anemia, Sickle Cell; Anti-Infl

2003