Page last updated: 2024-10-29

ketorolac and Iris Diseases

ketorolac has been researched along with Iris Diseases in 1 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Iris Diseases: Diseases, dysfunctions, or disorders of or located in the iris.

Research Excerpts

ExcerptRelevanceReference
"Men treated with tamsulosin having standard cataract extraction surgery were placed in a treatment group that received phenylephrine 1."2.87Effect of phenylephrine 1.0%-ketorolac 0.3% injection on tamsulosin-associated intraoperative floppy-iris syndrome. ( Juzych, MS; Nariman, N; Pankratz, J; Rana, S; Rana, VK; Segars, L; Silverstein, SM; Stephens, R, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Silverstein, SM1
Rana, VK1
Stephens, R1
Segars, L1
Pankratz, J1
Rana, S1
Juzych, MS1
Nariman, N1

Trials

1 trial available for ketorolac and Iris Diseases

ArticleYear
Effect of phenylephrine 1.0%-ketorolac 0.3% injection on tamsulosin-associated intraoperative floppy-iris syndrome.
    Journal of cataract and refractive surgery, 2018, Volume: 44, Issue:9

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and ov

2018