ketorolac has been researched along with Hypospadias in 1 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Nonsteroidal anti-inflammatory drug use is limited in hypospadias surgery due to concerns for post-operative bleeding, particularly with ketorolac." | 8.31 | Does ketorolac administration at the time of hypospadias surgery increase unplanned encounters in the immediate postoperative period? ( Canning, DA; Eftekharzadeh, S; Fombona, A; Hyacinthe, N; Kolon, TF; Long, CJ; Mittal, S; Shah, YB; Shukla, AR; Srinivasan, AK; Weinstein, C; Weiss, DA; Zaontz, MR, 2023) |
| " Nonsteroidal anti-inflammatory drug use is limited in hypospadias surgery due to concerns for post-operative bleeding, particularly with ketorolac." | 4.31 | Does ketorolac administration at the time of hypospadias surgery increase unplanned encounters in the immediate postoperative period? ( Canning, DA; Eftekharzadeh, S; Fombona, A; Hyacinthe, N; Kolon, TF; Long, CJ; Mittal, S; Shah, YB; Shukla, AR; Srinivasan, AK; Weinstein, C; Weiss, DA; Zaontz, MR, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mittal, S | 1 |
| Eftekharzadeh, S | 1 |
| Weinstein, C | 1 |
| Fombona, A | 1 |
| Hyacinthe, N | 1 |
| Shah, YB | 1 |
| Weiss, DA | 1 |
| Kolon, TF | 1 |
| Shukla, AR | 1 |
| Canning, DA | 1 |
| Srinivasan, AK | 1 |
| Zaontz, MR | 1 |
| Long, CJ | 1 |
1 other study available for ketorolac and Hypospadias
| Article | Year |
|---|---|
Does ketorolac administration at the time of hypospadias surgery increase unplanned encounters in the immediate postoperative period?
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Hypospadias; Ketorolac; | 2023 |