ketorolac has been researched along with Hyperemia in 8 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (50.00) | 29.6817 |
2010's | 4 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Crecelius, AR | 1 |
Luckasen, GJ | 1 |
Larson, DG | 1 |
Dinenno, FA | 2 |
Casey, DP | 2 |
Joyner, MJ | 5 |
Parker, BA | 1 |
Tschakovsky, ME | 1 |
Augeri, AL | 1 |
Polk, DM | 1 |
Thompson, PD | 1 |
Kiernan, FJ | 1 |
Lopez, MG | 1 |
Silva, BM | 1 |
Schrage, WG | 3 |
Dietz, NM | 1 |
Eisenach, JH | 1 |
Lorenzo, S | 1 |
Minson, CT | 1 |
2 trials available for ketorolac and Hyperemia
Article | Year |
---|---|
Roles of nitric oxide and prostaglandins in the hyperemic response to a maximal metabolic stimulus: redundancy prevails.
Topics: Blood Pressure; Enzyme Inhibitors; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Isch | 2013 |
Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans.
Topics: Aged; Aged, 80 and over; Aging; Blood Pressure; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female | 2007 |
6 other studies available for ketorolac and Hyperemia
Article | Year |
---|---|
KIR channel activation contributes to onset and steady-state exercise hyperemia in humans.
Topics: Adult; Barium Compounds; Chlorides; Cyclooxygenase Inhibitors; Exercise; Female; Forearm; Humans; Hy | 2014 |
Prostaglandins do not contribute to the nitric oxide-mediated compensatory vasodilation in hypoperfused exercising muscle.
Topics: Acetylcholine; Blood Pressure; Brachial Artery; Catheterization; Cyclooxygenase Inhibitors; Enzyme I | 2011 |
Heterogenous vasodilator pathways underlie flow-mediated dilation in men and women.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fema | 2011 |
Local inhibition of nitric oxide and prostaglandins independently reduces forearm exercise hyperaemia in humans.
Topics: Adult; Brachial Artery; Cyclooxygenase Inhibitors; Drug Combinations; Enzyme Inhibitors; Exercise; F | 2004 |
Effects of combined inhibition of ATP-sensitive potassium channels, nitric oxide, and prostaglandins on hyperemia during moderate exercise.
Topics: Adenosine Triphosphate; Adult; Enzyme Inhibitors; Exercise; Female; Forearm; Glyburide; Humans; Hype | 2006 |
Human cutaneous reactive hyperaemia: role of BKCa channels and sensory nerves.
Topics: Adult; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Hyperemia; Ketorolac; Large-Con | 2007 |