Page last updated: 2024-10-29

ketorolac and Headache

ketorolac has been researched along with Headache in 19 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Intranasal ketamine and intravenous ketorolac both effectively reduced headaches."9.51Comparison of the efficacy of intranasal ketamine versus intravenous ketorolac on acute non-traumatic headaches: a randomized double-blind clinical trial. ( Baigrezaii, H; Meysami, A; Nazarianpirdosti, M; Safari-Faramani, R; Sarvari, HR, 2022)
"Post-treatment with ketorolac was more effective in attenuating PACAP38-induced headache compared to sumatriptan."9.34Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache. ( Al-Karagholi, MA; Amin, FM; Arngrim, N; Ashina, M; Ghanizada, H; Larsson, HBW; Metcalf-Clausen, M; Mørch-Rasmussen, M, 2020)
"We compare metoclopramide 20 mg intravenously, combined with diphenhydramine 25 mg intravenously, with ketorolac 30 mg intravenously in adults with tension-type headache and all nonmigraine, noncluster recurrent headaches."9.17A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches. ( Adewunmi, V; Bijur, PE; Campbell, C; Esses, D; Friedman, BW; Gallagher, EJ; Solorzano, C, 2013)
"In a prospective, double-blind, randomized study, ketorolac 60 mg, meperidine 50 mg plus promethazine 25 mg, and normal saline given by intramuscular injection were compared as treatment for acute headache crises."9.08The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department. ( Carter, T; Gracely, RH; Harden, RN; Warner, G, 1996)
"Headache is one of the most common neurological conditions among emergency department visits (ED), although the best therapy has not been identified yet."7.01Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches. ( Eslami, K; Kouti, L; Majdinasab, N; Motamed, H; Soltani, KM, 2021)
"Intranasal ketamine and intravenous ketorolac both effectively reduced headaches."5.51Comparison of the efficacy of intranasal ketamine versus intravenous ketorolac on acute non-traumatic headaches: a randomized double-blind clinical trial. ( Baigrezaii, H; Meysami, A; Nazarianpirdosti, M; Safari-Faramani, R; Sarvari, HR, 2022)
"The objective of this study was to assess the efficacy and safety of a common monotherapy (intravenous [iv] metoclopramide) compared to a combination strategy (adding iv ketorolac to metoclopramide) in children presenting for acute treatment of migraine headache in the emergency department (ED)."5.51A randomized trial of ketorolac and metoclopramide for migraine in the emergency department. ( Ali, S; Johnson, DW; Newton, AS; Richer, LP; Rosychuk, RJ; Rowe, BH, 2022)
" Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need."5.41The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023)
"Post-ECT headache is typically treated with acetaminophen or nonsteroidal anti-inflammatory drugs but occasionally requires agents such as sumatriptan, opioids, or β-blockers."5.38Treatment of post-electroconvulsive therapy headache with topical methyl salicylate. ( Logan, CJ; Stewart, JT, 2012)
"Post-treatment with ketorolac was more effective in attenuating PACAP38-induced headache compared to sumatriptan."5.34Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache. ( Al-Karagholi, MA; Amin, FM; Arngrim, N; Ashina, M; Ghanizada, H; Larsson, HBW; Metcalf-Clausen, M; Mørch-Rasmussen, M, 2020)
"We compare metoclopramide 20 mg intravenously, combined with diphenhydramine 25 mg intravenously, with ketorolac 30 mg intravenously in adults with tension-type headache and all nonmigraine, noncluster recurrent headaches."5.17A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches. ( Adewunmi, V; Bijur, PE; Campbell, C; Esses, D; Friedman, BW; Gallagher, EJ; Solorzano, C, 2013)
"In a prospective, double-blind, randomized study, ketorolac 60 mg, meperidine 50 mg plus promethazine 25 mg, and normal saline given by intramuscular injection were compared as treatment for acute headache crises."5.08The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department. ( Carter, T; Gracely, RH; Harden, RN; Warner, G, 1996)
" Commonly used pharmacotherapies for primary headaches were intravenous dopamine receptor antagonists (69%), co-administration of ketorolac and a dopamine receptor antagonist (54."4.12Current practice for primary headache disorders and perspectives on peripheral nerve blocks among emergency physicians in Canada: A national survey. ( James, D; Patel, D; Perry, JJ; Taljaard, M; Yadav, K, 2022)
"Headache is one of the most common neurological conditions among emergency department visits (ED), although the best therapy has not been identified yet."3.01Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches. ( Eslami, K; Kouti, L; Majdinasab, N; Motamed, H; Soltani, KM, 2021)
" Efficacy assessments included pain intensity, which was measured on a 0- to 100-mm visual analog scale, total pain relief, and global pain evaluation up to 8 hours after dosing or until patients required rescue analgesia."2.75Intranasal ketorolac for pain secondary to third molar impaction surgery: a randomized, double-blind, placebo-controlled trial. ( Grant, GM; Mehlisch, DR, 2010)
"Post-ECT headache is typically treated with acetaminophen or nonsteroidal anti-inflammatory drugs but occasionally requires agents such as sumatriptan, opioids, or β-blockers."1.38Treatment of post-electroconvulsive therapy headache with topical methyl salicylate. ( Logan, CJ; Stewart, JT, 2012)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's4 (21.05)24.3611
2020's10 (52.63)2.80

Authors

AuthorsStudies
Soltani, KM1
Motamed, H1
Eslami, K1
Majdinasab, N1
Kouti, L1
Chowdhury, SS1
Shaw, M1
Berezowski, I1
Abdelmonem, A1
Patel, J1
Sarvari, HR1
Baigrezaii, H1
Nazarianpirdosti, M1
Meysami, A1
Safari-Faramani, R1
Atif, H1
McGhee, J1
Patel, D1
Taljaard, M1
Yadav, K1
James, D1
Perry, JJ2
Richer, LP1
Ali, S1
Johnson, DW1
Rosychuk, RJ1
Newton, AS1
Rowe, BH2
Abdelmonem, H1
Abdelhay, HM1
Abdelwadoud, GT1
Alhosini, ANM1
Ahmed, AE1
Mohamed, SW1
Al-Dardery, NM1
Abd-ElGawad, M1
Kamel, MA1
Ghanizada, H1
Al-Karagholi, MA1
Arngrim, N1
Mørch-Rasmussen, M1
Metcalf-Clausen, M1
Larsson, HBW1
Amin, FM1
Ashina, M1
Wells, S1
Stiell, IG1
Vishnyakova, E1
Lun, R1
Nemnom, MJ1
Saeedi, M1
Shahvaran, SM1
Ramezani, M1
Rafiemanesh, H1
Karimialavijeh, E1
Villa-Roel, C1
Krebs, LD1
Friedman, BW1
Adewunmi, V1
Campbell, C1
Solorzano, C1
Esses, D1
Bijur, PE1
Gallagher, EJ1
De Cesaris, F1
Fanciullacci, M1
Pietrini, U1
Anselmi, B1
Del Bene, E1
Grant, GM1
Mehlisch, DR1
Logan, CJ1
Stewart, JT1
Rossi, P1
Nappi, G1
Harden, RN1
Gracely, RH1
Carter, T1
Warner, G1
McConnell, EA1
Morgenstern, LB1
Huber, JC1
Luna-Gonzales, H1
Saldin, KR1
Grotta, JC1
Shaw, SG1
Knudson, L1
Frankowski, RF1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects[NCT03585894]34 participants (Actual)Interventional2018-08-01Completed
An RCT of Metoclopramide/Diphenhydramine vs. Ketorolac Alone for Tension-type Headache[NCT01011673]Phase 4123 participants (Actual)Interventional2009-11-30Completed
The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031]Phase 454 participants (Actual)Interventional2016-03-17Completed
A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872]Phase 4500 participants (Actual)Interventional2017-09-05Terminated (stopped due to no longer recruiting or studying)
Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130]Phase 458 participants (Actual)Interventional2017-05-16Completed
Evaluating Post-operative Pain Management Efficacy of Intra Nasal Ketorolac in Ambulatory Urological Surgeries-A Randomized Double-blinded Placebo Controlled Study[NCT01736358]Phase 450 participants (Actual)Interventional2012-10-31Terminated (stopped due to Interim analysis showed futility of primary endpoint)
Improving the Headache Management Care in the Emergency Unit by Using a Biological Marker: S100B Protein.[NCT03490500]63 participants (Actual)Observational2018-10-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Pain Score

At baseline at at 60 minutes, all patients were asked to describe their pain on a scale from 0 to 10, with 0 representing no pain and 10 the worst imaginable. The primary outcome is the 60 minute score subtracted from the baseline score (NCT01011673)
Timeframe: Baseline, 60 minutes

Interventionunits on a scale (Mean)
Ketorolac3.8
Metoclopramide5.1

Satisfaction Scores

"24 hours after the emergency department visit, patients were asked, The next time you come to the Er with this type of headache, do you want to receive the same medication? Affirmative answers are tabulated here." (NCT01011673)
Timeframe: 24 hours

Interventionparticipants (Number)
Ketorolac45
Metoclopramide53

Anxiety

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm33.7
Study Arm21.2

Headache Following Intervention

Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm63.5
Study Arm43.5

Nausea

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm38.9
Study Arm22.9

The Number of Participants Experiencing Vomiting

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm2
Study Arm3

The Number of Patients Experiencing Restlessness

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm3
Study Arm3

Incidence of Postoperative Side Effects

To find the incidence of immediate (until discharge) and 24hrs post operative side effects in the target population. (NCT01736358)
Timeframe: 24 hours after procedure

Interventionnumber of events (Number)
Intranasal Ketoralac0
Placebo0

Post Operative Pain Scale

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 2 hours after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 2 hours after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac4
Placebo3

Post Operative Pain Score

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 1 hour after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 1 hour after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac3.5
Placebo4.5

Post Operative Pain Score

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 30 minutes after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 30 minutes after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac4
Placebo3.5

Post-operative Opioid Requirements

this study will assess the effect of perioperative usage of single-dose of intranasal ketorolac on post operative opioid requirements within 3 hours after surgery. (NCT01736358)
Timeframe: 3 hours after surgery

Interventionmg (Median)
Intranasal Ketoralac27.43
Placebo30

Reviews

1 review available for ketorolac and Headache

ArticleYear
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
    BMC neurology, 2023, Jun-08, Volume: 23, Issue:1

    Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea

2023

Trials

9 trials available for ketorolac and Headache

ArticleYear
Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches.
    The American journal of emergency medicine, 2021, Volume: 50

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dopamine D2 Receptor An

2021
IV metoclopramide Vs IV ketorolac in the treatment of acute primary headaches: A randomized clinical trial.
    The American journal of emergency medicine, 2022, Volume: 56

    Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Headache; Humans; Ketorola

2022
Comparison of the efficacy of intranasal ketamine versus intravenous ketorolac on acute non-traumatic headaches: a randomized double-blind clinical trial.
    Head & face medicine, 2022, Jan-03, Volume: 18, Issue:1

    Topics: Administration, Intranasal; Analgesics; Double-Blind Method; Headache; Humans; Ketamine; Ketorolac

2022
A randomized trial of ketorolac and metoclopramide for migraine in the emergency department.
    Headache, 2022, Volume: 62, Issue:6

    Topics: Adolescent; Child; Double-Blind Method; Emergency Service, Hospital; Headache; Humans; Ketorolac; Me

2022
Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache.
    The journal of headache and pain, 2020, Feb-24, Volume: 21, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Hea

2020
Comparing the effects of 3 oxygen delivery methods plus intravenous ketorolac on primary headaches: A randomized clinical trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:1

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hosp

2020
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
    Annals of emergency medicine, 2013, Volume: 62, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind

2013
Intranasal ketorolac for pain secondary to third molar impaction surgery: a randomized, double-blind, placebo-controlled trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Administration, Intranasal; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhi

2010
The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department.
    Headache, 1996, Volume: 36, Issue:6

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

1996

Other Studies

9 other studies available for ketorolac and Headache

ArticleYear
Randomized IV metoclopramide vs IV ketorolac in treatment of acute primary headache.
    The American journal of emergency medicine, 2022, Volume: 57

    Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Headache; Humans; Ketorola

2022
Current practice for primary headache disorders and perspectives on peripheral nerve blocks among emergency physicians in Canada: A national survey.
    Headache, 2022, Volume: 62, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Canada; Dopamine Antagonists; Emergency Service, Hospital;

2022
Optimal management strategies for primary headache in the emergency department.
    CJEM, 2021, Volume: 23, Issue:6

    Topics: Adult; Emergency Service, Hospital; Female; Headache; Humans; Ketorolac; Metoclopramide; Migraine Di

2021
How to diagnose and treat benign headaches.
    CJEM, 2019, Volume: 21, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dopamine D2 Receptor Antagonists; Drug Thera

2019
Defining neuralgiform headache with ipsilateral autonomic symptoms: case report in a headache center.
    Internal and emergency medicine, 2008, Volume: 3, Issue:4

    Topics: Aged; Amines; Analgesics, Opioid; Anticonvulsants; Autonomic Nervous System; Cyclohexanecarboxylic A

2008
Treatment of post-electroconvulsive therapy headache with topical methyl salicylate.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Depressive Disorder, Major;

2012
Bath-related headache: the first European case.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:12

    Topics: Adrenergic beta-Antagonists; Analgesics; Baths; Female; Headache; Humans; Hypertension; Ketorolac; M

2006
When your postoperative patient has a setback.
    Nursing, 1996, Volume: 26, Issue:10

    Topics: Adult; Analgesics, Non-Narcotic; Dizziness; Female; Headache; Humans; Ketorolac; Nursing Assessment;

1996
Headache in the emergency department.
    Headache, 2001, Volume: 41, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Diagnosis, Differential; Drug T

2001