ketorolac has been researched along with Glaucoma in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma." | 7.70 | Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998) |
| "Between July 2005 and October 2007, 61 consecutive medically uncontrolled glaucoma patients scheduled for first-time trabeculectomy were randomized to 1 of 3 study topical medication groups: nonsteroidal anti-inflammatory drugs (ketorolac), steroids (fluorometholone), or placebo (artificial tears)." | 5.14 | Preoperative nonsteroidal anti-inflammatory drug or steroid and outcomes after trabeculectomy: a randomized controlled trial. ( Breusegem, C; Fieuws, S; Renier, C; Spielberg, L; Stalmans, I; Van de Veire, S; Van Ginderdeuren, R; Vandewalle, E; Zeyen, T, 2010) |
| "To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma." | 3.70 | Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breusegem, C | 1 |
| Spielberg, L | 1 |
| Van Ginderdeuren, R | 1 |
| Vandewalle, E | 1 |
| Renier, C | 1 |
| Van de Veire, S | 1 |
| Fieuws, S | 1 |
| Zeyen, T | 1 |
| Stalmans, I | 1 |
| Callanan, D | 1 |
| Fellman, RL | 1 |
| Savage, JA | 1 |
1 trial available for ketorolac and Glaucoma
| Article | Year |
|---|---|
Preoperative nonsteroidal anti-inflammatory drug or steroid and outcomes after trabeculectomy: a randomized controlled trial.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihyper | 2010 |
1 other study available for ketorolac and Glaucoma
| Article | Year |
|---|---|
Latanoprost-associated cystoid macular edema.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; G | 1998 |