ketorolac has been researched along with Glaucoma, Suspect in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients older than 18 years with intraocular pressure (IOP) of more than 18 mmHg for whom the clinician decided SLT was the appropriately indicated therapy were randomized to 1 of 3 groups in a ratio of 1:1:1 as follows: ketorolac 0." | 5.30 | SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy. ( Albeiruti, E; Fajardo, R; Goldberg, JL; Groth, SL; Loewen, N; Nunez, M; Schuman, JS; Sharpsten, L, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Orlans, HO | 1 |
| Yazdouni, S | 1 |
| Williamson, TH | 1 |
| Wong, RS | 1 |
| Laidlaw, DAH | 1 |
| Groth, SL | 1 |
| Albeiruti, E | 1 |
| Nunez, M | 1 |
| Fajardo, R | 1 |
| Sharpsten, L | 1 |
| Loewen, N | 1 |
| Schuman, JS | 1 |
| Goldberg, JL | 1 |
1 trial available for ketorolac and Glaucoma, Suspect
| Article | Year |
|---|---|
SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy.
Topics: Administration, Ophthalmic; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fema | 2019 |
1 other study available for ketorolac and Glaucoma, Suspect
| Article | Year |
|---|---|
A Novel Postoperative Drop Regimen Reduces Risk of Ocular Hypertension Following Pars Plana Vitrectomy.
Topics: Dexamethasone; Humans; Ketorolac; Ocular Hypertension; Postoperative Complications; Retrospective St | 2023 |