ketorolac has been researched along with Eye Disorders in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Results of HET-CAM and ICE tests suggest that sulphacetamide is moderately toxic in the presence of light/UV-A and very slightly irritant without irradiation." | 1.40 | Photochemical toxicity of drugs intended for ocular use. ( Kaithwas, G; Kishor, K; Sahu, RK; Saraf, SA; Singh, B, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sahu, RK | 1 |
| Singh, B | 1 |
| Saraf, SA | 1 |
| Kaithwas, G | 1 |
| Kishor, K | 1 |
| Gupta, AK | 1 |
| Madan, S | 1 |
| Majumdar, DK | 1 |
| Maitra, A | 1 |
2 other studies available for ketorolac and Eye Disorders
| Article | Year |
|---|---|
Photochemical toxicity of drugs intended for ocular use.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chickens; Diclofenac; Eye Diseases; Humans; Irrit | 2014 |
Ketorolac entrapped in polymeric micelles: preparation, characterisation and ocular anti-inflammatory studies.
Topics: Acrylamides; Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Excipients; | 2000 |