Page last updated: 2024-10-29

ketorolac and Experimental Spinal Cord Ischemia

ketorolac has been researched along with Experimental Spinal Cord Ischemia in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hsieh, YC2
Liang, WY1
Tsai, SK1
Wong, CS2
Cheng, H1
Chan, KH1
Chang, WK1
Liu, TM1

Other Studies

2 other studies available for ketorolac and Experimental Spinal Cord Ischemia

ArticleYear
Intrathecal ketorolac pretreatment reduced spinal cord ischemic injury in rats.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Injections, Spinal; Ketorolac; Male;

2005
Protective effect of intrathecal ketorolac in spinal cord ischemia in rats: a microdialysis study.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Chromatography, High Pressure Liquid;

2007