ketorolac has been researched along with Endophthalmitis in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topete, A | 1 |
| Serro, AP | 1 |
| Saramago, B | 1 |
| Kohnen, T | 1 |
| Sahu, S | 1 |
| Ram, J | 1 |
| Bansal, R | 1 |
| Pandav, SS | 1 |
| Gupta, A | 1 |
| Waterbury, LD | 1 |
| Galindo, D | 1 |
| Villanueva, L | 1 |
| Nguyen, C | 1 |
| Patel, M | 1 |
| Borbridge, L | 1 |
| Attar, M | 1 |
| Schiffman, RM | 1 |
| Hollander, DA | 1 |
1 trial available for ketorolac and Endophthalmitis
| Article | Year |
|---|---|
Effect of topical ketorolac 0.4%, nepafenac 0.1%, and bromfenac 0.09% on postoperative inflammation using laser flare photometry in patients having phacoemulsification.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Be | 2015 |
3 other studies available for ketorolac and Endophthalmitis
| Article | Year |
|---|---|
Dual drug delivery from intraocular lens material for prophylaxis of endophthalmitis in cataract surgery.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Dru | 2019 |
Treating inflammation after lens surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Benzophenones; Bromobenzenes; Endophthal | 2015 |
Ocular penetration and anti-inflammatory activity of ketorolac 0.45% and bromfenac 0.09% against lipopolysaccharide-induced inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Benzophenones; Bromobenzenes; Dextr | 2011 |